Accès ouvert déclaré 2016 article

Cause of Death and Predictors of All‐Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF

Sean D. Pokorney, Jonathan Paul Piccini, Susanna R. Stevens, Manesh R. Patel, Karen S. Pieper, Jonathan L. Halperin, Günter Breithardt, Daniel E. Singer, Graeme J. Hankey, Werner Hacke, Richard C. Becker, Scott D. Berkowitz, Christopher C. Nessel, Kenneth W. Mahaffey, Keith A.A. Fox, Robert M. Califf, Jonathan Anderson, Noel W. Bedwell, Martin Bilsker, G. Keith Bruce, Ramtin Agah, Marshall DeSantis, Steven J. Eisenberg, A. Flores, Wolfgang Herzog, SUSAN A. KLEIN, Harvey A. Snyder, Steven K. Krueger, Erasmo de la Peña-Almaguer, EFI LAVIE, C. Lee, G. Mallis, Manish Modi, Graeme F. Woodworth, Imran K. Niazi, Brenda Peart, Sri Sundaram, Brian Snoddy, Rodolfo P. Sotolongo, John B. Moloney, Kris Vijayaraghavan, F. Whittier, L. Yellen, Subhash Banerjee, Daniel Lawrence Lustgarten, Dr.S Suresh, M. Gelernt, L Levinson, R. Ghanekar, G. Larsen Kneller, Christian Hall, Yazid Y. Fadl, Mark J. Pirwitz, William J. French, Nolan J. Mayer, Jian Bianca Pugeda, Kevin E. Steel, Freny Vaghaiwalla Mody, Amir Z. Malik, Humza Chandna, Alan S. Go, George Emlein, William W Bowden, Roberto Moscoso, Ruth Hodson, Michael Berk, Dengji Pan, Janine M. Pappas, Robert C. Orchard, G. Lynchard, Nampalli K. Vijay, Waqor Khan, Maher Khadra, Mark C Antonishen, Fred Cucher, Michael E. Staab, James S. Zebrack, S Borromeo, Jacqueline M. Heilman, Seemant Chaturvedi, Sravya Makam, Samir Turk, Thomas M. Hyers, George Washington Williams, Ajay Labroo, SK Gill, Donald W. Myears, Jean Marc Weinstein, Jeffrey G. Shanes, Yellapragada Chandrashekhar, Surbhi Shah, William M. Reiter, Tim Logemann, Adrian K. Almquist, Ravi Bhagwat, Tahir Tak, J. Shen‐Ling, Priyesh Ashok Patel, Andre Artis, Amy J. Arouni, Michael R. Lauer, Kurt G. Kinney, J. Elsen, P G Roan, R. Villafria, Matthew T. Sumpter, James E. Ip, Stephen J. Welka, Branislav Schifferdecker, Robert Hernan Sandoval, Shawn Speirs, Aubrey E. Jones, Thomas Haldis, John F. Kazmierski, Julie Sutherland, Denise Felber Dietrich, Edward Telfer, Joni I. Berry, Alvin Mcelveen, James Knox Russell, Melanie K. Sackett, Nathalie Antonios, David W. Smith, Kishor N. Vora, Ann Kirby, Hin-Wai LUI, David M. Mego, Khaled M. Ziada, José Casals Navas, Andrew S. Taussig, Michael J. Koren, Craig Vogel, Federica Saba, Charles W. Parrott, Ralf A. Schneider, Arsalan Shirwany, Mark N. Rubin, Charles B. Treasure, Barry D. Bertolet, Mark F. Chang, Jonathan J. Langberg, Yves Cohen, Frank A. McGrew, Jentora White, F. Arzola, J Zelenka, Alan K. Tannenbaum, Vera Fernandes, P. Jamnadas, J. Agamasu, Bradley Collins, Werner Jauch, Brett M. Sasseen, David R. Hotchkiss, R. Abadier, A. Osunkoya, A. Schlau, Clifford I. Chappel, Malcolm T Foster, Eyal Braun, Edward Mostel, Jaïr Dilmé Capó, Majdi Ashchi, Virginia J. Howard, Abdulhay Albirini, Alfred Burger, Daniel M. Rolston, Cezar S. Staniloae, Jenny Louise Bacon, Anthony C. Wiseman, Jeremy R. McGarvey, Ali F. Sonel, Glenn S. Hamroff, Donald S. Chang, Nizar Daboul, George T Broderick, A. Meholick, John Corbelli, R Silverman, J.D. Raffetto, Robert D. Fishberg, Steven Georgeson, Jolene Held, Matt Seidner, Henock Saint-Jacques, John F. Heitner, Steven P. Kutalek, Ida K Friedlander, Barry Donald Hutchinson, J. S. WALIA, Naoto Kondo, Nasser Smiley, Lawrence R. Blitz, Heather Dale, S. Sulman, Ireneusz Szulawski, Fariba Modares, ADIL M. AL-NAHHAS, Michael J. Renzi, Ayim Akyea-Djamson, Alessandra Alfieri, Jasreen Kaur Sandhu, Stephen J. Voyce, Sudhir Amaram, Gary Meyerrose, Mohammad Shoukfeh, F. Lee, Bernard J. Villegas, Olakunle Idowu, Amit V. Khera, Colleen Sam, Amanda X. Vo, Ira H. Lieber, Tyler Smith, Najam A. Awan, Chuan-Tsai Tsai, Ricky Ganim, Ghassan J. Al-Zaghrini, William A. J. Pitt, April Shepherd, Sherman Tang, S. Stoltz, Winnie W. Nelson, Sharon Elizabeth Cox, Sheba Meymandi, Mike B. Melucci, G. Neil Thomas, Harinder S. Gogia, Charles Machell, Suresh Chandrasekaran, Claire Brown, Preetham Jetty, Gary D. Miller, Gail S Dykstra, Naseem Jaffrani, Bishoy Zakhary, Arturo Armone Caruso, R. Zolty, David J. Fox, George B. Jacobs, Mark Lebenthal, S Mukherjee, PETER J. ZIMETBAUM, Jr Jw Kingsley, Russel Jones, Victoria M. Robinson, D. Kenton, James E. Usedom, Sarah Williams, C. Snipes, V. Wilson, Robert T. Hasty, J. Kevin Shoemaker, Mark Donahue, Youssef M Al-Saghir, Erik Vilain Thomsen, Steven A. Yarows, S. Chastain, Paul McLaughlin, M. Dean Wakham, Dhan Bahadur Shrestha, Jeffrey D. Simmons, Dennis M. Fisher, Zachary Seymour, Brad Frandsen, Brian First, Claire C. Sharpe, Larry Popeil, Robert M. Guthrie, James M. Hunter, Olga Franco Alvarado, Jacob Sandberg, Ned H Gutman, Arthur D. Belber, Mikhail V Arkhipov, M. F. Ballyzek, Aleksey A. Baranov, О. Л. Барбараш, V. B. Barbarich, Dmitry Belenky, О. А. Беркович, Igor N. Bokarev, Mikhail Boyarkin, S B Vaniev, Е. В. Волкова, N. A. Gratsiansky, Dëmin Aa, Zadionchenko Vs, Dmitry A. Zateyshchikov, Konstantin Zrazhevsky, Vladimir P. Mazaev, Martynov Ai, С. С. Михайлов, В. Р. Мкртчян, В Г Новоженов, Tatiana A. Raskina, Andrey P. Rebrov, Natalia P. Sanina, V. Simanekov, Maria Sitnikova, Olga G. Smolenskaya, R. I. Stryuk, G. Storozhakov, B. M. Tankhilevich, S. N. Тereschenko, А. Л. Хохлов, Олег Антонинович Хрусталев, Sergey A. Chernov, Yu. G. Shvarts, Yu. V. Shubik, Shul'man Va, S. S. Yakushin, О. В. Бугрова, A Ia Ivleva, Roman A. Libis, Natalya V. Khozyainova, Sergei Maslov, Е. И. Баранова, Alexander Sherenkov, И. А. Либов, V. A. Lusov, Galina A. Chumakova, Kuznetsov Va, IN Ryamzina, O. V. Reshetko, Svetlana A. Boldueva, Nina P. Alekseeva, T Novikova, В. Е. Дворников, Е. М. Идрисова, Nadezhda A. Shostak, Natalya Yarokhno, К. И. Теблоев, Tatiana V. Treshkur, Mazurov Vi, Evgeny M. Loktin, I. Sedavnyh, Olga V. Alexeeva, Polina K Yakhontova, Alexey N. Repin, Nadezhda V. Izmozherova, В. А. Костенко, А. А. Фокин, Galina G. Ketova, Simon Kouz, Rolland Leader, F. Ayala Paredes, R. Luton, Peizhi Ma, Shivda Pandey, Yves Pesant, Roxy Senior, Gergely Vértes, Alan David Bell, Declan Crowley, Saul Vizel, Ben Lasko, Daniel L. Landry, Léo Berger, John A. Heath, Ricardo Bessoudo, Ming Qiang Ling, Guy Tellier, Joseph Berlingieri, Henryk P. Kafka, Linda Hill, Giuseppe A Mazza, William F O’Mahony, Mark A. Chilvers, M. O'Mahony, Darrell Brian Newman, S. Silagy, Michael P. Heffernan, Matthew T. Bennett, T. Bhesania, Gary E. Rockman, Kuan H. Ng, Bhupinder Singh Kalra, Gladys Meneses, Wenyi Liang, Michael Cheung, J Kozák, G. Pugen, J. Vavougios, Max R. Kates, C. Nunes‐Vaz, Sara Jaffer, J. Orfi, A. Faiers, Chang‐Ming Chung, S. Felsen, Scott Bergman, Inge Bernstein, Larry M. Brownscombe, J. Stockdill, Eric S. Silver, Dorcas Ezekiel, Nirmala Jagan, Mona Khurana, HYMAN REISLER, Harold B. Goldman, Thein Lin Maung, Frankie A. Wong, Garry Gillis, R M Vexler, B Goldberg, M. Luterman, Doug William Gould, Benoit Coutu, Annie Ouellet, Paul C. MacDonald, Mathew C. Jones, R. Collette, Pang H Chong, Terence Fargher, François St-Maurice, Claude Fortin, Raja Chehayeb, Guy Proulx, Ranjini Raina Roy, Joanne Liutkus, G. Syan, Dennis Wayne Rupka, Theresa Lichtenstein, Jacobus Kooy, D. Papastergiou, Bruce J. Lubelsky, Werner Doyle, Akila Rajakumar, Jae‐Kwan Cha, A. Choudhry, H. Bhamjee, Alishah Mawji, M. Durfresne, Christian Constance, J. Mutrie, A. Najarali, Roderick J. Warren, Marta Mucha, David J. Borts, P. Nord, Serge Carrier, Murtaza Y. Dawood, Georges Sabe-Affaki, Jess Archibald, Nargis Abram, EARL J. TEITELBAUM, Iftikhar O Ebrahim, Reiner Siebert, Louis van Zyl, Hantie Theron, Elin Fflur Lloyd, Robin Sommers, Gracjan Podgorski, L Steingo, Anthony J. Dalby, Junaid Bayat, Laurel H. Herbst, Frederik Bester, Cynthia F. Corbett, James D. Bennett, Adolfo Rafael de Roodt, Jean-François Roux, Mark Jonathan Abelson, Zahretelwady Mohamed Salaheldin Mohamed, H. Nortje, A. Da Silva, K. Nikolaides, K. Liagkas, E. Papasteriadis, A. D. Achimastos, N. Koliopoulos, Athanasios G. Trikas, Antonis S. Manolis, JAAP H. RUITER, Dick C.G. Basart, Harry J.G.M. Crijns, Adrie J.A.M. Withagen, Mirian C. H. Janssen, Robert Langeveld, Isabelle C. Van Gelder, Bas Hamer, Rob van der Heijden, D. Hertzeberger, Maarten van Hessen, Mathijs Pieterse, RGEJ Groutars, Adrianus F.M. Kuijper, Gijsbert de Ruiter, Ad van Boven, Pieter A.M. Hoogslag, Hans Kragten, Henk O.M. Thijssen, Rolf F. Veldkamp, Christophe Scavée, Hein Heidbüchel, Philippe Debruyne, Bernard Deruyter, Hussam Ali, Marnix Goethals, R. Cytryn, Harry Striekwold, Luc De Wolf, Peter Goethals, Frank Provenier, Steven Hellemans, Michel Galinier, D Coisne, Andreas Köenig, D. Galley, Sylvain Destrac, James W. LeDuc, Abdelhadi Rifai, Bruce A. Citron, Emmanuel Ellie, Pierre-Yves Fournier, Philippe Gabríel Steg, R. Landel, Anna M.C. Robinson, Franz von Ziegler, J Boulliat, Mathieu Zuber, M Vida, Enrique Galve Basilio, Mariano Casado López, Carlos Iñiguez, L. Iglesias Alonso, M. Cavero Gibanel, Jorge Martinez, Francisco Calvo, Jordi Bruguera Cortada, A. Jaber Houbani, José Luís Merino, Fernando Olaz Preciado, Jorge Balaguer, JM De La Hera Galarza, Antoni Martínez‐Rubio, J. Fontcuberta, Joan Martí, José Ramón González‐Juanatey, Raquel Del Campo, P. Alvarez Garcia, M.P. Sáinz Pelayo, J Lippai, Károly Zámolyi, T. Károly, András Vértes, Attila Csaba Nagy, István Kósa, Alexander Janosi, Géza Lupkovics, Eyal Kalo, Tamás Forster, ERNO KIS, József Tenczer, Dániel Bereczki, Samuel Komoly, Attila Csányi, Róbert Gábor Kiss, A. Valikovics, Péter Diószeghy, Francesco Masini, Pierfranco Terrosu, Vincenzo Cirrincione, Claudio Marabotti, Federica Cosmi, Alessandro Salvioni, Giorgio Binetti, G Piovaccari, D. Nassiacos, Giuseppe Boriani, Valeria Ilia Calvi, Raffaele De Caterina, Vittorio Pengo, Gianfranco Parati, Antonio Carolei, Angela D’Angelo, Matteo Di Biase, Luciano Fattore, Giancarlo Agnelli, Piera Angelica Merlini, Maria Montserrat Dias Pedrosa Furlan, Maurizia Rasura, Carlo Gandolfo, Walter Ageno, Franco Piovella, Giuseppe Micieli, Mircea Cintezǎ, Carmen Fierbinteanu, D. Natase‐Melicovici, Dan Dominic Ionescu, Cezar Macarie, Ioan Tiberiu Nanea, Mariana Rădoi, S. I. Dragulescu, Alexandra Ana Maria Tudose, Constantin Militaru, Cristina M Bengus, Georgeta Mihaela Ungureanu, ANCA TAU, V. Popa, Octavian M. Pirvu, Mihai Bojinca, Doina Sipciu, Mircea Ioachim Popescu, M. Chiru, Dragoş Vinereanu, Mariana Tudoran, T. Cojocaru, MARIUS MARCIAN VINTILA, G. Aron, Ovidiu Petrascu, Filip Romi Bolohan, R. Baumgärtner, Lučka Šekoranja, Jan Vojáček, Bořek Lačňák, Ivana Kellnerova, Milan Dunaj, C Cíhalík, Tomáš Janota, Jan Janoušek, P. Bouchal, R Spacek, J. Choi Siruckova, Petr Heinc, Pavel Vojtišek, Marian Pirchala, Jeremy Malecha, František Paďour, Aleš Linhart, Eva Mandysová, J Jandík, E. Zidkova, David Šipula, Rostislav Polášek, V. Stransky, GABRIEL MARCINEK, Dana Ryšavá, Pavel P. Osmancik, Kurt Huber, Heinz Drexel, Michael Brainin, Sabine Eichinger-Hasenauer, Wilfried Lang, E Pilger, Andrew Moriarty, Ian L. Hudson, Kok Foo Tang, John G.F. Cleland, Ronald S. MacWalter, John P. Cooke, Gordon T. McInnes, Ramesh Durairaj, Malcolm Robert Macleod, David L. Murdoch, Honer Kadr, Gregory Y.H. Lip, Richard V. Andrews, Benjamin D. Hunt, Pamela Braboy Jackson, Christine Roffe, Philip M. Bath, John J. Coyle, Deborah F. Kelly, Stefan Stender, Christian Tobias Torp-Pedersen, Christian Tuxen, Gorm Boje Jensen, Thomas Maria Melchior, KIM KLARLUND, Carolin Maria Dahlström, Tonny Nielsen, Eric Steen Nielsen, Jens Brønnum-Schou, Roman Sykulski, Per Blomström, Carl-Johan Lindholm, Thomas Wallén, Carina Nilsson, Eric Bertholds, J. Carlsater, Per Anton Sirnes, Sigbjørn Elle, Knut Risberg, Kristian Furuseth, A. Skag, Hans Olav Høivik, N. Landmark, Thorbjørn Kjærnli, Jan Berg-Johansen, G. Gradek, Artur Drzewiecki, Władysław Pluta, Hanna Szwed, Maria Trusz‐Gluza, Marcin Ogorek, Krystyna Łoboz−Grudzień, Piotr Ruszkowski, Ryszard Ściborski, Jerzy Kopaczewski, Kinga Jaworska, Jacek Kubica, Grzegorz Opolski, Andrzej Hoffman, Małgorzata Krzciuk, Włądysław Sinkiewicz, Walerian Piotrowski, Piotr Kołodziej, M. Goszczynska, Andrzej Rynkiewicz, Lidia Chojnowska, Jerzy Lewczuk, M. Biedrzycka, Marta Piepiorka, Joanna Kowal, Agnieszka Karczmarczyk, Piotr Pruszczyk, Michał Tendera, Zbigniew A. Gaciong, Maria Krzemińska‐Pakuła, Z Kornacewicz-Jach, Grzegorz Kania, Johannes Brachmann, Holger Lawall, H. Guelker, Stefan G. Spitzer, Sven Moebius‐Winkler, Carl-Erik Dempfle, Christoph Bode, Harald Darius, Sabine Genth‐Zotz, SP Sommer, Jens-Uwe Roehnisch, R. H. Strasser, Wilfried Daenschel, Carsten Schwencke, Jürgen vom Dahl, M. Meuser, S. Behrens‐Spandau, S. Behrens‐Humbold, A. Muegge, Norbert Schoen, Peter Grooterhorst, H.-H. Ebert, A. X. Elzo Kraemer, B.C. Köhler, Jens Taggeselle, G. Claus, H-E Sarnighausen, Ayham Al-Zoebi, Tim Schroeder, Matthias Weißbrodt, Ruediger Lange, Matthias Gabelmann, Stefan Kaeaeb, M Doerr, D. Boscher, RALPH F. BOSCH, Frank Sonntag, Christian Bauknecht, Heyder Omran, Michael J. Leicht, Roland C. Veltkamp, H. Hohensee, H. Dieckmann, Bernhard Rudolf Winkelmann, Peter Bernhardt, A. Schnabel, C Kadel, N Proskynitopoulos, Karolina Seidl, SEBASTIAN M. SCHELLONG, C. Rios, Carolina Guevara, Ramón Coloma, H. Torrejon, J. Parra Galvan, J. Drago Silva, Juan J. Gallegos, Sandra Adela Negron, Lígia Moriguchi Watanabe, Felix Alvaro Medina, L. Virgen Carrilo, Humberto Alvarez Lopez, Iria Beltrán Rodríguez, Jose Luis Leiva-Pons, Alejandro Velasco, Jorge Villarreal-Careaga, Martínez Ríos, Massimo Gamba, G Llamas Esperon, E. Villeda, Andrea A. Guerrero, A. Alvariqueta, Marcos Amuchástegui, Jorge Blüguermann, Guillermo D. Caime, Carlos Alberto Cuneo, A. Gabito, Daniela García Brasca, MIGUEL ANGEL HOMINAL, Horacio O. Jure, Hugo A Luquez, Oscar R. Montaña, Daniel Leonardo Piskorz, S. Listorti, J. Serra, H. Sessa, Sergio D. Varini, N Vita, Jorge Roberto Aiub, Ignacio J. Mackinnon, Sergio Chekherdemian, Jorge P. Castagnino, J. Cimbaro Canella, H Sgammini, Aldo Edwin Rodriguez Escudero, Gastón Albina, Carlos Rapallo, Cecilia Balparda, Michael Chahin, Victorino Fuentealba, Miguel Angel Riccitelli, José H Casabé, L. Lobo Marquez, Rubén Kevorkián, Jesus Cuadrado, RICARDO DARIO DRAN, Juan Antonio Muntaner, Marta Sánchez González, Luis Rodolfo Cartasegna, Eduardo Hasbani, Adrian D. Hrabar, Dominik J. Vogel, Alejandro Hershson, Álvaro Avezum, Jeffrey Jaber, Paulo Ernesto Leães, A Bozza, Adalberto Lorga Filho, Pinto Filho, Jesus Jorge, Lília Nigro Maia, Euler Roberto Fernandes Manenti, R D'Aurea Mora, João de Souza Coelho Neto, Dalton Bertolim Précoma, Á Rabelo, Afonso Rocha, P Rossi, J. Kerr Saraiva, Leandro Ioschpe Zimerman, Luiz Carlos Bodanese, Estêvão Lanna Figueiredo, Weimar sebba Barroso de Souza, J. Braga, Sílvio Roberto Borges Alessi, Marco Antônio Mota Gomes, Rafael Paletta da Silva, Marcia Fabrícia Almeida Teixeira, Francesco Costa, Massimo Motta, Dário Sobral Filho, Gilmar Reis, B Garbelini, Sérgio Luiz Zimmermann, Antonio P. Barretto, HF Dohmann, Jose B Araujo Filho, Nabil Ghorayeb, Flavio Antonio de Oliveira Borelli, Fabio Rossi dos Santos, Maurício Prudente, Matthew Vejar, Fernando Tomas Lanas, Sergio Potthoff, Gustavo Charme, Alfons Aguirre, Agustin Sancho Saldaña, Eduardo Garcés, L. Bunster, Horacio Figueroa, Claudia Olivares, Carmelo Raffo, E. Vergara, Pablo Sepúlveda, Gabriel Jano, Jacqueline Alvarado, Rafael Suárez, Gabriela Perez, Andres Quintero, L. Fernando Pava, Ralph Lopez, Carlos Luengas, Edgar Javier Hernandez, David Martí Sánchez, Cristina Cambra Poveda, Julián Coronel, Raúl Carrillo Beltrán, Carlos Alberto Jaramillo, C. Ponte Negretti, Jesús Isea, Gastón Vergara-Hermosilla, Igor Morr, K.H. Sim, Waheed Ahmad, Zurkurnai Yusof, Azhari Rosman, Hamidon Basri, Paul A. Thompson, Ian Jeffery, P. Purnell, Peter J. Roberts-Thomson, WILLIAM F. HEDDLE, Jonathon H. Waites, D. Walters, John V. Amerena, Pavan Challa, Jeff Karrasch, Andrew J. Lowy, David R. Fitzpatrick, MW Parsons, Thanh G. Phan, Christopher Bladin, Geoffrey Alan Donnan, G. Aroney, Richard P Gerraty, Craig S. Anderson, Peter A. Blombery, Paul Martín, Tissa Wijeratne, David B. Cross, Denis S. Crimmins, David Packham, Daniel J. Jackson, Winnie Chua, Rosa María García Merino, Michael G. Magno, Louie S. Tirador, Elfred B. Batalla, Chriselda G Manalo, Natalie F. Uy, Geraldine Ebo, Eugene B. Reyes, Alisa Bernan, Mark Richards, Hamish H. Hart, Samuel J. Mann, Raewyn Fisher, Ralph Stewart, GERARD T. WILKINS, A. J. Barber, Ru‐San Tan, Hean Yee Ong, Robby Singh, Apichard Sukonthasarn, Supachai Tanomsup, Rungroj Krittayaphong, Chumpol Piamsomboon, Dilok Piyayotai, Buncha Sunsaneewitayakul, Sang Hong Baek, H. Seo, Se‐Joong Rim, C. Kim, K. Kim, Kum Hei Ryu, Ström JO, S J Tahk, H. Lee, Y. Kim, Dong‐Gu Shin, Youngsook Choi, Natali A. Y. Chung, June Namgung, Taek Jong Hong, Wan-Sik Shin, Song Jin, Xue Yan, Guohua Fu, Genmin Lu, Kuang-Tsu Yang, Dong Zhu Xu, Jocelyn Chen, Jun G Liu, Shuyi Wu, Ji Young Song, Ying‐Chieh Liao, Bin Xu, Z. Li, Shuren Ma, Yiwei Yin, Yingxin Zhao, Dayi Hu, Changsheng Ma, Jianyong Ma, J F Sun, Haiyang Li, Xuejiao Hong, Ben Hui Yu, Qiang Lü, Jian Ming Yang, Zhaohui Wu, Y. Li, Yu‐Tung Huang, Y. Wang, Mingyou Liu, Yun‐Jiu Cheng, Ten-Fang Yang, K. Chen, H. Wang, Zuyi Yuan, J. Wang, Zhiwei Zeng, Y. Chen, O. Yavuzgil, Ömer Kozan, Mumin Etemoglu, Erdem Diker, Avinash Belgi, Ceyhun Ceyhan, Ömer Yılmaz, Naim Ata, Bülent Behlül Altunkeser, Ayşen Ağaçdiken Ağır, Aziz Karadede, Ramazan Topsakal, Rajiv Gulati, Arjun Madhavan, Sandeep K Jain, Abraham Oomman, Satej Janorkar, Pradeep Kumar, Ajay Madhukar Naik, Hemant P Thacker, Vunnam Rajasekhar, Ramakota Reddy, C B Keshavamurthy, Pankaj Jain, B. Gowdappa, Milind Avdhoot Gadkari, Atul Damodar Abhyankar, Bandi Ramesh Babu, P.R. Vydianathan, Sunil Kumar Sinha, Neha Garg, Shufang Rao, PL Gautam, Kumaravelu Chockalingam, Mukund Kumbla, Rajesh Panwar, Darshan Navinchandra Banker, Markku Kaste, Pekka A. Jäkälä, Risto O. Roine, Atanas Mihov, Dimitar H. Raev, V. Yordanova, S. Dimitrova, Haralambi O Benov, Veska Tsanova, M. Kyolean, Sotir T. Marchev, Anastas Stoikov, Nikolai G. Zdravkov, K. Ramshev, Athanas Krastev, Paraskeva Stamenova, I Angelova, G. Pencheva, Valentina Grigorova, Birutė Petrauskienė, I. Skripkauskiene, Rasa Raugalienė, Sigutė Norkienė, R. Mazutavicius, Aušra Kavoliūnienė, Sigita Aidietienė, Jūratė Aganauskienė, A. Dailydkiene, Jolanta Elena Marcinkevičienė, L. Grigoniene, J. Anusauskiene, Roma Kavaliauskiene, V. G. Lizogub, Л И Руденко, Vira Tseluyko, Leonid Georgievich Voronkov, O. S. Sychov, Yevgeniya Svyshchenko, Yuriy Sirenko, В К Серкова, Nestor M. Seredyuk, Tetyana Pertseva, V. Z. Netyazhenko, Viktoriia Y Lishnevska, O. Kupchynska, Olena Koval, Г Н Кошукова, Oleksandr Karpenko, O. Grishyna, A. Faynyk, G. V. Dzyak, O. Dyadyk, L.M. Yena, В Е Волков, Iurii Stepanovich Rudyk, M. P. Kopytsya, L. Kononenko, Amosova En, Svitlana Zhurba, V. Kazimirko, I. Iuzkiv, O. Shershnyova, Tetyana Khomazyuk, Valeriy Batushkin, I. Vykhovanyuk, G. Popik, V. Skrebkov, A. Skurtov, Tamara S. Mishchenko, Nataliya V. Lytvynenko, Л. И. Соколова, M. T. Vatutin, М. І. Швед, Б. А. Ребров, L. Kadina, M. Vajda, Григорий Николаевич Урсол, V. Zheleznyy, T.G. Vysochanska, Anatoliy I. Gozhenko, K Fan, D. Ho, Hung‐Fat Tse, Cheuk‐Man Yu, Ka Sing Wong, Hung‐I Yeh, Paresh Pai, Ching‐Lin Hsieh, Chun‐Yao Huang, Yu‐Cheng Hsieh, Wei-Hsian Yin, L M Tsai, Ting‐Chun Huang, C. Chen, Fu‐Tien Chiang, K.-C. Ueng, Min Ji Charng, Alon T Marmor, Amos Katz, Adi Butnaru, Basil S. Lewis, M. Eldar, S. Rosenhack, Nora Elias, Bella Koifman, Michael Kleiner Shochat, Moshe Swissa, Reuven Zimlichman, Tamir Bental, A. Weiss, Rasem Ganam, Merrill F. Elias, William Nseir, Arie Oliven, Benjamin Brenner, Molly Dayan

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15Institutions déclarées
4Pays d’affiliation déclarés

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Le résumé fourni par la source

BACKGROUND: Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. METHODS AND RESULTS: In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose-adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all-cause mortality in the 14 171 participants in the intention-to-treat population. The median age was 73 years, and the mean CHADS2 score was 3.5. Over 1.9 years of median follow-up, 1214 (8.6%) patients died. Kaplan-Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all-cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33-1.70, P<0.0001) and age ≥75 years (hazard ratio 1.69, 95% CI 1.51-1.90, P<0.0001) were associated with higher all-cause mortality. Multiple additional characteristics were independently associated with higher mortality, with decreasing creatinine clearance, chronic obstructive pulmonary disease, male sex, peripheral vascular disease, and diabetes being among the most strongly associated (model C-index 0.677). CONCLUSIONS: In a large population of patients anticoagulated for nonvalvular atrial fibrillation, ≈7 in 10 deaths were cardiovascular, whereas <1 in 10 deaths were caused by nonhemorrhagic stroke or systemic embolism. Optimal prevention and treatment of heart failure, renal impairment, chronic obstructive pulmonary disease, and diabetes may improve survival. CLINICAL TRIAL REGISTRATION: URL: https://www.clinicaltrials.gov/. Unique identifier: NCT00403767.

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Le contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref
Cause of Death and Predictors of All‐Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF
Date Crossref
09/03/2016
Éditeur
Ovid Technologies (Wolters Kluwer Health)
Type
journal-article

Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.

Où se fait cette recherche

  • Clinical Research Institute pays non établi dans la notice
    Structure de recherche
  • Duke Medical Center pays non établi dans la notice
    Établissement de santé
  • Mount Sinai Medical Center pays non établi dans la notice
    Établissement de santé
  • University of Münster Department of Cardiovascular Medicine pays non établi dans la notice
    Université ou école supérieure
  • University Hospital Münster pays non établi dans la notice
    Établissement de santé
  • Harvard University pays non établi dans la notice
    Université ou école supérieure
  • Massachusetts General Hospital pays non établi dans la notice
    Établissement de santé
  • Singer (United States) pays non établi dans la notice
    Entreprise
  • Royal Perth Hospital Department of Neurology pays non établi dans la notice
    Établissement de santé
  • Heidelberg University pays non établi dans la notice
    Université ou école supérieure
  • Bayer (United States) pays non établi dans la notice
    Entreprise
  • Janssen (United States) pays non établi dans la notice
    Entreprise

Clinical Research Institute, Duke Medical Center et Mount Sinai Medical Center, avec 9 autres affiliations.

Une affiliation ne permet pas de déduire la nationalité d’un auteur.

Les sujets associés

Atrial Fibrillation Management and OutcomesVitamin K Research StudiesVenous Thromboembolism Diagnosis and Management
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