John Corbelli

Interleukin 6 and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Chronic Coronary Syndrome

Gorav Batra, Tatevik Ghukasyan Lakic, Johan Lindbäck, Claes Held et autres

Importance: Inflammation promotes cardiovascular disease and anti-inflammatory treatment reduces cardiovascular events in patients with chronic coronary syndrome. Chronic kidney disease (CKD) is a risk factor for cardiovascular disease. It is unclear how inflammation mediated by interleukin 6 (IL-6) in patients with CKD …

se, nz, de, us, pl (code pays fourni par la source)

193 Edoxaban versus warfarin on stroke risk in patients with atrial fibrillation: a territory-wide cohort study

Che Him Dicken Kong, Jiandong Zhou, Sharen Lee, Keith Sai Kit Leung et autres

Background In this territory-wide, observational, propensity score-matched cohort study, we evaluate the development of transient ischaemic attack and ischaemic stroke (TIA/Ischaemic stroke) in patients with AF treated with edoxaban or warfarin. Methods This was an observational, territory-wide cohort study of patients between …

hk, fr, cn, us (code pays fourni par la source)

Edoxaban versus warfarin on stroke risk in patients with atrial fibrillation: a territory-wide cohort study

Dicken Kong, Jiandong Zhou, Sharen Lee, Keith Sai Kit Leung et autres

Abstract Background In this territory-wide, observational, propensity score-matched cohort study, we evaluate the development of transient ischaemic attack and ischaemic stroke (TIA/Ischaemic stroke) in patients with AF treated with edoxaban or warfarin. Methods This was an observational, territory-wide cohort study of patients …

hk, gb, cn, us (code pays fourni par la source)

SAFETY AND EFFICACY OF NOVEL ORAL ANTICOAGULANTS COMPARED TO WARFARIN IN PATIENTS WITH CANCER AND ATRIAL FIBRILLATION: META-ANALYSIS

Bhavi Pandya, Srilekha Sridhara, Emrie D. Tomaiko, Abhishek Chandrakant Sawant et autres

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Superior safety of direct oral anticoagulants compared to Warfarin in patients with atrial fibrillation and underlying cancer: a national veterans affairs database study.

Abhishek Chandrakant Sawant, Arnav Kumar, Wilmon McCray, Sheldon J. Tetewsky et autres

BACKGROUND: Studies evaluating safety of warfarin and direct oral anticoagulants (DOACs) for prevention of stroke in patients with atrial fibrillation (AF) are lacking. METHODS & RESULTS: = 0.04. CONCLUSIONS: We demonstrated the superior safety profile of DOACs compared to warfarin among patients …

us, hk, cn (code pays fourni par la source)

Evaluation of YouTube as a reliable source for patient education on aortic valve stenosis

Charl Khalil, Michael S. Megaly, Catherine Ekladios, Amira Ibrahim et autres

Background: Aortic stenosis (AS) is a prevalent disease in the elderly population and has been a public health concern for decades. YouTube is currently being used for obtaining healthcare related information. We evaluated the quality of information about AS on YouTube for …

us, Égypte (code pays fourni par la source)

Mesalamine-induced Myocarditis in a Young Athlete: Can He Run Again?

Amira Ibrahim, Charl Khalil, Michael S. Megaly, Mariam Tawadros et autres

Mesalamine is often used in the treatment of inflammatory bowel disease (IBD). Mesalamine-induced cardiotoxicity has been reported in the literature and is a rare entity. The mechanism of cardiotoxicity remains unclear, however, it is believed to be due to a humoral-mediated hypersensitivity …

Égypte, us (code pays fourni par la source)

A Partial Anomalous Pulmonary Venous Connection in a Severely Symptomatic Patient, Is Surgery Always Recommended?

Charl Khalil, Wassim Mosleh, Amira Ibrahim, Herbert A. Young et autres

Partial anomalous pulmonary venous connection (PAPVC) is a rare cardiac anomaly occurring when a pulmonary vein drains into the right atrium, coronary sinus or a systemic vein creating a left-to-right shunt. Symptoms develop from right-sided fluid overload and pulmonary vascular disease. We …

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Mono versus Dual Antiplatelet Therapy after Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis

Charl Khalil, Wassim Mosleh, Michael S. Megaly, Sumeet Gandhi et autres

Background Dual antiplatelet therapy (DAPT) is routinely prescribed after transcatheter aortic valve replacement (TAVR) despite the lack of definitive data demonstrating its superiority over mono-antiplatelet therapy (MAPT). We aim to investigate the benefits of DAPT versus MAPT and at different follow-up time …

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Quality of life outcomes in transcatheter aortic valve replacement patients requiring pacemaker implantation

Aishwarya Bhardwaj, Tharmathai Ramanan, Abhishek Chandrakant Sawant, Everett Sinibaldi et autres

Abstract Background Permanent pacemaker implantation is the most common complication after Transcatheter aortic valve replacement (TAVR) and is associated with worse outcomes and mortality. However, its impact on quality‐of‐life (QoL) outcomes remains unknown. Methods We included 383 consecutive patients undergoing TAVR from …

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Fractional flow reserve guided percutaneous coronary intervention results in reduced ischemic myocardium and improved outcomes

Abhishek Chandrakant Sawant, Aishwarya Bhardwaj, Kinjal Banerjee, Yash B. Jobanputra et autres

OBJECTIVES: To determine if fractional flow reserve guided percutaneous coronary intervention (FFR-guided PCI) is associated with reduced ischemic myocardium compared with angiography-guided PCI. BACKGROUND: Although FFR-guided PCI has been shown to improve outcomes, it remains unclear if it reduces the extent of …

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Temporal Trends, Complications, and Predictors of Outcomes Among Nonagenarians Undergoing Percutaneous Coronary Intervention

Abhishek Chandrakant Sawant, Kevin Josey, Mary E. Plomondon, Thomas M. Maddox et autres

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