Shuyi Wu

Outcomes in patients with atrial fibrillation with and without heart failure on oral anticoagulants: a multicenter retrospective cohort study

Xiaomin Dong, Shuyi Wu, Xinhai Huang, Yanxian Lan et autres

BACKGROUND: Multicenter real-world data on anticoagulated patients with atrial fibrillation (AF) and heart failure (HF) remain limited, particularly in Chinese populations. This study compared clinical outcomes in AF patients receiving oral anticoagulants (OACs) according to HF status. METHODS: We conducted a multicenter …

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Adebrelimab with or without induction chemotherapy followed by concurrent chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma (RICE): A prospective, phase 2 trial.

Shuyi Wu, Yong Yang, Tiantian Zhai, Shiliang Liu et autres

314 Background: The prognosis for locally advanced esophageal squamous cell carcinoma (LAESCC) remains poor.This study aims to investigate the efficacy and safety of Induction immunotherapy in unresectable LAESCC. Methods: RICE is a prospective, two-arm clinical study. Patients aged 18–70 years with untreated, …

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A clinical prediction model for blood pressure changes after renal denervation in patients with resistant hypertension

Yuejia Zhang, Rui-Qing He, Chen Chen, Hong Zhang et autres

Objective: To develop clinical prediction models to estimate blood pressure changes in hypertensive patients undergoing renal denervation (RDN). Methods: This single-center, prospective interventional study enrolled 70 hypertensive patients undergoing RDN between July 2022 and December 2023, with clinical data collected systematically before …

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Global burden and attributable risk factors of inflammatory cardiomyopathy and myocarditis from 1990 to 2019

Guilan Wu, Wenlin Xu, Shuyi Wu, Chengfu Guan et autres

BACKGROUND: Our understanding of the global burden distribution of inflammatory cardiomyopathy and myocarditis is very limited. OBJECTIVE: To comprehensively assess the global burden distribution and attributable risk factors of inflammatory cardiomyopathy and myocarditis from 1990 to 2019. METHODS: We extracted the data …

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Efficacy and safety of rivaroxaban in preventing venous thromboembolism in postoperative patients with gynecological malignancies: protocol for a randomised controlled open-label trial (G-alfalfa trial)

Hong Zhou, Shuyi Wu, Fei He, Huan Yi et autres

INTRODUCTION: Compared with the guideline-recommended use of low-molecular weight heparin (LMWH) for 28 days to prevent venous thromboembolism (VTE) after cytoreductive surgery, oral rivaroxaban avoids the pain and inconvenience of daily injections and reduces medical expenses. The proposed randomised controlled trial (RCT) …

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The Alfalfa-inpatient-CAT assessment model: a thrombotic risk assessment model for inpatient cancer patients

Wenjun Chen, Guilan Wu, Peiguang Niu, Shuyi Wu et autres

To construct a venous thromboembolism (VTE) risk assessment model specifically for inpatients with cancer. Patients were included according to the inclusion criteria. Univariate and multivariate analyses of all variables were included to develop a VTE risk assessment model applicable to the derivation …

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Efficacy and safety of direct oral anticoagulants for preventing venous thromboembolism in hospitalized cancer patients: a national multicenter retrospective cohort study

Shuyi Wu, Haiping Wang, Chunbao Li, Jingjing Tao et autres

Introduction Studies on the use of direct oral anticoagulants (DOACs) for preventing venous thromboembolism (VTE) in hospitalized cancer patients are lacking. Therefore, we conducted a multicenter retrospective cohort study to evaluate the efficacy and safety of DOACs versus low-molecular-weight heparin (LMWH) for …

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Development of a Routine Serological Test Index Panel for the Surveillance of Gastric Cancer Risk in a High-Risk Population.

Mengmeng Wang, Zengyan Zong, Shuyi Wu, Xu Chen et autres

OBJECTIVE: This study aims to develop a predictive model for the detection of gastric cancer risk utilizing non-invasive parameters and to assess the model's effectiveness in risk stratification for gastric cancer (GC). METHODS: A case-control study was conducted among inpatients with various …

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Efficacy and safety of direct oral anticoagulants in patients with atrial fibrillation combined with chronic kidney disease: a systematic review and meta-analysis

Yaodi Li, Shuyi Wu, Jintuo Zhou, Jinhua Zhang

BACKGROUND: Currently published studies have not observed consistent results on the efficacy and safety of direct oral anticoagulants (DOACs) use in patients with chronic kidney disease (CKD) combined with atrial fibrillation (AF). Therefore, this study conducted a meta-analysis of the efficacy and …

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Risk factors for anticoagulant-associated gastrointestinal hemorrhage: a systematic review and meta-analysis

Fuxin Ma, Shuyi Wu, Shiqi Li, Zhiwei Zeng et autres

BACKGROUND/AIMS: There may be many predictors of anticoagulation-related gastrointestinal bleeding (GIB), but until now, systematic reviews and assessments of the certainty of the evidence have not been published. We conducted a systematic review to identify all risk factors for anticoagulant-associated GIB to …

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Safety and efficacy of direct oral anticoagulants in stroke prevention in patients with atrial fibrillation complicated with anemia and/or thrombocytopenia: a retrospective cohort study

Wenlin Xu, Jiana Chen, Shuyi Wu, Nianxu Huang et autres

Abstract Background There are limited data about the clinical benefits and harm of direct oral anticoagulants (DOACs) in stroke prevention in patients with atrial fibrillation (AF) complicated with anemia or thrombocytopenia. Methods This is a multi-center retrospective cohort study involving 5469 AF …

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Global, regional, and national burden of ischaemic heart disease and its trends, 1990–2019

Chengfu Guan, Shuyi Wu, Wenlin Xu, Jinhua Zhang

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