Takashi Shiga

Rapid Antigen Detection Testing for Group A Streptococcus as an Adjunct for Early Diagnosis of Necrotizing Soft Tissue Infection: A Case Series

Kaiho Hirata, Naoki Shida, Haruka Tsuji, Takuyo Chiba et autres

Necrotizing soft tissue infection (NSTI) is a rapidly progressive, life-threatening soft-tissue infection most commonly caused by group A Streptococcus (GAS). Although early diagnosis and prompt surgical intervention are crucial, the initial presentation is often nonspecific, which can occasionally delay diagnosis and surgical …

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A Case of a Young Patient With Necrotizing Soft Tissue Infection Caused by Community-Acquired Methicillin-Resistant Staphylococcus aureus

Ryuhei Igeta, Reina Sasaki, Tetsuya Matsumoto, Hiroshi Kaneko et autres

(MRSA) is a well-known pathogen, community-acquired MRSA (CA-MRSA) is an uncommon cause of NSTI, especially in otherwise healthy pediatric patients. We report the case of a previously healthy 13-year-old boy who developed NSTI of the lower extremity after sustaining a trivial insect …

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Enhancement on productivity and sustainability with the world’s first 6 kHz KrF light source G65K

Takashi Shiga, Yuuki Takeda, Daisuke Tei, Hideyuki Ochiai et autres

Semiconductor manufacturers today are facing increasing social pressure to enhance sustainability while needing to simultaneously boost productivity. Gigaphoton has addressed these demands by developing G65K, the world’s first 6 kHz KrF light source. Thanks to the integration of proven GT laser technologies, …

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Association of level 3 personal protective equipment with intubation success in the emergency department

Takashi Shiga, Takuyo Chiba, Yutaka Fujishima, Yusuke Hagiwara et autres

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Regional Comparison in Cerebral Performance Outcome of Out-of-Hospital Cardiac Arrest: The All-Japan Utstein Registry

Ryuhei Igeta, Shunichi Otaka, Takahiro Imaizumi, Kentaro Kajino et autres

BACKGROUND: Past studies have reported regional differences in the prognosis of out-of-hospital cardiopulmonary arrest (OHCA) in Japan, but there is a lack of sufficient information to explain the changes in neurological prognosis over time. METHODS: Using the All-Japan Utstein Registry, a nationwide …

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Polyarteritis nodosa with splenic rupture and multiple cerebral infarctions

Yuta Norimatsu, Aiko Saku, Hirotoshi Kawashima, Takuya Minagawa et autres

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Comparing the effects of microgravity and amyotrophic lateral sclerosis on mouse dorsal root ganglia

Masaaki Yoshikawa, Mutsumi Matsukawa, Hideki Oshima, Chihiro Ishikawa et autres

Introduction: Microgravity (MG) exposure causes motor deficits and decreased neuronal activity, effects that resemble the ones observed in motor neuron diseases such as amyotrophic lateral sclerosis (ALS). Several recent studies have shown that exposure to MG and ALS also impacts the sensory …

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A Survey of Near-Miss Dispensing Errors in Hospital Pharmacies in Japan: DEPP-J Study—Multi-Center Prospective Observational Study—

Kenji Momo, Takeo Yasu, Seiichiro Kuroda, Sonoe Higashino et autres

The aim of this study was to determine the proportion of near-miss dispensing errors in hospital pharmacies in Japan. A prospective multi-center observational study was conducted between December 2018 and March 2019. The primary objective was to determine the proportion of near-miss …

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Biodegradable and Electrically Conductive Melanin‐Poly (3‐Hydroxybutyrate) 3D Fibrous Scaffolds for Neural Tissue Engineering Applications

Lokesh Agrawal, Sunil Kumar Vimal, P. Barzaghi, Takashi Shiga et autres

Due to the severity of peripheral nerve injuries (PNI) and spinal cord injuries (SCI), treatment options for patients are limited. In this context, biomaterials designed to promote regeneration and reinstate the lost function are being explored. Such biomaterials should be able to …

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Comparing effects of microgravity and amyotrophic lateral sclerosis in the mouse ventral lumbar spinal cord

Masaaki Yoshikawa, Chihiro Ishikawa, Haiyan Li, Takashi Kudo et autres

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The Association between Physician Involvement During Pediatric Out-of- Hospital Cardiac Arrest and Patient Outcomes: a Japanese Nation-Wide Observational Study

Shunichi Otaka, Hiroyuki Ohbe, Ryuhei Igeta, Takuyo Chiba et autres

Background: The effectiveness of physician involvement during out-ofhospital cardiac arrest has been shown in adults but remains unknown in pediatric patients. This study aimed to investigate the association between physician involvement during pediatric out-of-hospital cardiac arrest and patient outcomes. Methods: Using a …

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Transcriptome analysis of sevoflurane exposure effects at the different brain regions

Hiroto Yamamoto, Y. UCHIDA, Tomoki Chiba, Ryota Kurimoto et autres

BACKGROUNDS: Sevoflurane is a most frequently used volatile anesthetics, but its molecular mechanisms of action remain unclear. We hypothesized that specific genes play regulatory roles in brain exposed to sevoflurane. Thus, we aimed to evaluate the effects of sevoflurane inhalation and identify …

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