Sunil Kumar Vimal

Drug Delivery to the Brain: Targeting Technologies to Deliver Therapeutics to Brain Lesions

Nishit Pathak, Sunil Kumar Vimal, Sanjib Bhattacharya

Delivering therapeutics to brain always remains an open challenge for drug delivery. Endothelial tight junction, astrocytes, and basal lamina of brain, which is collectively called as blood–brain barrier, serve as a tough nutshell for the restricted entry of solutes, metabolites, and molecular …

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Biodegradable and Electrically Conductive Melanin‐Poly (3‐Hydroxybutyrate) 3D Fibrous Scaffolds for Neural Tissue Engineering Applications

Lokesh Agrawal, Sunil Kumar Vimal, P. Barzaghi, Takashi Shiga et autres

Due to the severity of peripheral nerve injuries (PNI) and spinal cord injuries (SCI), treatment options for patients are limited. In this context, biomaterials designed to promote regeneration and reinstate the lost function are being explored. Such biomaterials should be able to …

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In vivo and in silico investigations of the pegylated gold nanoparticle treatment of amyotrophic lateral sclerosis in mice

Sunil Kumar Vimal, Hongyi Cao, Amit Dubey, Lokesh Agrawal et autres

Amyotrophic lateral sclerosis (ALS) is a lethal disease that involves the progressive annihilation of motor neurons.

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Neurodegenerative Disorders of Alzheimer, Parkinsonism, Amyotrophic Lateral Sclerosis and Multiple Sclerosis: An Early Diagnostic Approach for Precision Treatment

Nishit Pathak, Sunil Kumar Vimal, Ishi Tandon, Lokesh Agrawal et autres

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Synthesis of Some Bioactive Nanomaterials and Applications of Various Nanoconjugates for Targeted Therapeutic Applications

Sabyasachi Chakrabortty, Sunil Kumar Vimal, Sanjib Bhattacharya

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Self‐Therapeutic Nanoparticle That Alters Tau Protein and Ameliorates Tauopathy Toward a Functional Nanomedicine to Tackle Alzheimer's

Sunil Kumar Vimal, Hua Zuo, Zhengwu Wang, Hongrun Wang et autres

Tauopathy is a complex disorder associated at the junction of several other pathologies. Intrinsically disordered tau protein remains therapeutically challenging due to its undruggable nature and is a possible reason for monumental failure of several tau-based therapies. Herein, nanogold remodeled tau is …

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Therapeutic potential of serotonin 4 receptor for chronic depression and its associated comorbidity in the gut

Lokesh Agrawal, Mustafa Korkutata, Sunil Kumar Vimal, Manoj Kumar Yadav et autres

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Corrigendum to ‘Role of serotonin 4 receptor in the growth of hippocampal neurons during the embryonic development in mice’

Lokesh Agrawal, Sunil Kumar Vimal, Takashi Shiga

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Role of serotonin 4 receptor in the growth of hippocampal neurons during the embryonic development in mice

Lokesh Agrawal, Sunil Kumar Vimal, Takashi Shiga

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An Idea of Using Microneedles for the Targeted Drug Delivery to Overcome the Blood Brain Barrier for the Treatment of Brain Diseases

Lokesh Agrawal, Sunil Kumar Vimal, Minhua Chen, Takashi Shiga

Background: Cardiovascular patients are more often reported with drug-drug interactions as compared to patients with other diseases. The high rate of prescribed drugs in elderly patients increases the likelihood of drug interactions and thus the risk that drugs themselves can be the …

A simple method for fabrication of electrospun fibers with controlled degree of alignment having potential for nerve regeneration applications

Sunil Kumar Vimal, Nadim Ahamad, Dhirendra S. Katti

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Anti-bacterial activity of herbal extracts, EuMiL® and antibiotics against Helicobacter muridarum

Sunil Kumar Vimal, Varsha Sharma, M Bhatnagar

Aims The aim of this research was to investigate the anti-bacterial activity of herbal extracts of Asparagus racemosus Wild (AR), Centella asiatica Linn (CA). Convolvulus pluricaulis (CP), Emblica officinalis (EO), Ocimum sanctum (OS) and Withania somnifera Dunal (WS), a polyherbal drug EuMil® …