Lokesh Agrawal

Shortwave infrared imaging–guided radiosensitization using rare-earth-doped nanoparticles delivered via microneedles for enhanced melanoma therapy

Mohd Yaqub Khan, Jen‐Kun Chen, Lokesh Agrawal, Garima Joshi et autres

Abstract Melanoma remains a major global health challenge due to the uncontrolled growth of abnormal skin cells, resistance to conventional therapies, and poor prognosis in advanced cases. Localized, early-stage melanoma, defined as melanoma confined to the skin without regional or distant spread, …

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The Influence of Surface Modification on the Shortwave Infrared Emission of Rare-Earth-Doped Nanoparticles

Mohd Yaqub Khan, Jen‐Kun Chen, Vivek Kumar Jain, Lokesh Agrawal et autres

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Weak Biophoton Emission Reveals Gateway To The Past

Carlo Monsanto, Andreea Petruse, Lokesh Agrawal

Our team has spent over 20 years gathering observational data from citizen scientists and conducting research and development to create a new approach to learning called "quantum social learning" or QSL. QSL focuses on the most subtle aspects of human experience, known …

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Biodegradable and Electrically Conductive Melanin‐Poly (3‐Hydroxybutyrate) 3D Fibrous Scaffolds for Neural Tissue Engineering Applications

Lokesh Agrawal, Sunil Kumar Vimal, Paolo Barzaghi, Takashi Shiga et autres

Due to the severity of peripheral nerve injuries (PNI) and spinal cord injuries (SCI), treatment options for patients are limited. In this context, biomaterials designed to promote regeneration and reinstate the lost function are being explored. Such biomaterials should be able to …

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Abstract 2791: Integrating biospecimen science approaches into clinical assay development-PAR 22-049

Lokesh Agrawal, Abhi Rao, Ping Guan, Miguel R. Ossandon et autres

Abstract Introduction to the problem: Biospecimens are the essential starting materials for the biomarker assays that enable precision medicine. Biospecimen preanalytical factors can directly influence molecular results from assays conducted for basic research, biomarker discovery, and biomarker validation, and can also influence …

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Allosteric Modulation of Adenosine A2A Receptors as a New Therapeutic Avenue

Mustafa Korkutata, Lokesh Agrawal, Michael D. Lazarus

The therapeutic potential of targeting adenosine A2A receptors (A2ARs) is immense due to their broad expression in the body and central nervous system. The role of A2ARs in cardiovascular function, inflammation, sleep/wake behaviors, cognition, and other primary nervous system functions has been …

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POST MYOCARDIAL INFARCTION SUB-TRICUSPID VALVE PSEUDOANEURYSM- A LESSON FOR NOVICE ECHOCARDIOGRAPHER

Rakesh Kumar Ola, Manish Ruhela, Mukesh Kumar, Lokesh Agrawal

A case of post tricuspid valve pseudoaneurysmoccurring 10 days after inferior wall myocardial infarction and diagnosed on trans-thoracic echocardiography.To the best of our knowledge, this is the first reported case of such a complication at sub-tricuspid location.

Use of Microfluidics Chambers to Image Axonal transport in Adult Sensory Neurons

Maria Fransiska Emily, Lokesh Agrawal, Paolo Barzaghi, Miki Otsuki et autres

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In vivo and in silico investigations of the pegylated gold nanoparticle treatment of amyotrophic lateral sclerosis in mice

Sunil Kumar Vimal, Hongyi Cao, Amit Dubey, Lokesh Agrawal et autres

Amyotrophic lateral sclerosis (ALS) is a lethal disease that involves the progressive annihilation of motor neurons.

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Neurodegenerative Disorders of Alzheimer, Parkinsonism, Amyotrophic Lateral Sclerosis and Multiple Sclerosis: An Early Diagnostic Approach for Precision Treatment

Nishit Pathak, Sunil Kumar Vimal, Ishi Tandon, Lokesh Agrawal et autres

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Development of 3D culture scaffolds for directional neuronal growth using 2-photon lithography

Lokesh Agrawal, Menouer Saidani, Laurent Guillaud, Marco Terenzio

Conventional applications of transplant technology, applied to severe traumatic injuries of the nervous system, have met limited success in the clinics due to the complexity of restoring function to the damaged tissue. Neural tissue engineering aims to deploy scaffolds mimicking the physiological …

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Abstract 2632: Fostering engagement in biobanking and research through the NCI Cancer Moonshot Biobank patient and provider engagement website

Esmeralda Casas-Silva, Lokesh Agrawal, Helena Judge Ellis, Veena Gopalakrishnan et autres

Abstract The National Cancer Institute's (NCI) Cancer Moonshot Biobank (the Biobank) aims to accelerate cancer research on treatment resistance and sensitivity through collection of longitudinal biospecimens and health data donated by participants diagnosed with late-stage cancer and receiving standard of care therapy …

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