Seiichiro Kuroda

A phase II study evaluating the preventive effect of topical hydrocortisone for capecitabine-induced hand-foot syndrome in patients with colorectal cancer receiving adjuvant chemotherapy with capecitabine plus oxaliplatin (T-CRACC study)

Yohei Iimura, Keisuke Baba, Naoki Furukawa, Masaaki Ishibashi et autres

BACKGROUND: Topical steroids may help prevent capecitabine-induced hand-foot syndrome in patients with colorectal cancer, as inflammation is involved in anti-tumor agent-induced hand-foot syndrome development. We assessed the preventive efficacy of medium-class topical corticosteroids for capecitabine-induced hand-foot syndrome in patients receiving adjuvant chemotherapy …

jp (code pays fourni par la source)

A Literature Review and Management Approach for Severe Skin Toxicity Induced by Enfortumab Vedotin Through Sequential Adaptation and Combination With Immune Checkpoint Inhibitors

Yohei Iimura, Seiichiro Kuroda, Sachie Kaichi, Kisumi Yomoda et autres

In patients with advanced urothelial carcinoma who have progressed after platinum-based chemotherapy, enfortumab vedotin (EV) improves overall survival compared to standard chemotherapy. Additionally, for treatment-naïve patients with locally advanced or metastatic urothelial carcinoma, the combination of pembrolizumab and EV demonstrates superior efficacy …

jp, kr (code pays fourni par la source)

A phase II study evaluating the preventive effect of topical hydrocortisone for capecitabine-induced hand-foot syndrome in patients with colorectal cancer receiving adjuvant chemotherapy with capecitabine plus oxaliplatin (T-CRACC study)

Yohei Iimura, Keisuke Baba, Naoki Furukawa, Masaaki Ishibashi et autres

jp (code pays fourni par la source)

A randomized, double-blind, placebo-controlled phase III study evaluating the preventive effect of diclofenac cream on capecitabine-related hand-foot syndrome: study protocol of J-SUPPORT2401/JORTC-SUP06 (J-DIRECT)

Yohei Iimura, Hiroshi Ishiguro, Hironobu Hashimoto, Masanori Nojima et autres

BACKGROUND: Clinical evidence on preventive therapy for capecitabine-induced hand-foot syndrome (HFS) is limited, and moisturizing and avoiding local pressure are recommended in guidelines. Although the precise pathogenesis and mechanisms of HFS remain unclear, inflammatory reactions are thought to be involved. The preventive …

jp, us (code pays fourni par la source)

A randomized, double-blind, placebo-controlled phase III study evaluating the preventive effect of diclofenac cream on capecitabine-related hand-foot syndrome: Study protocol of J-SUPPORT2401/JORTC-SUP06 (J-DIRECT)

Yohei Iimura, Hiroshi Ishiguro, Hironobu Hashimoto, Masanori Nojima et autres

jp, Nigéria (code pays fourni par la source)

Examination of the Optimal Environment of Unilateral Laminar-Flow Clean Benches for Sterile Preparation Based on Wind Velocity Measurements

Seiichiro Kuroda, Anna Kiyomi, Shinobu Imai, Munetoshi Sugiura

A clean bench is necessary for maintaining an environment compliant with Class 5 of the International Organization for Standardization 14644-1 (ISO Class 5), ensuring airflow through the workspace with a mean wind velocity of 0.3-0.6 m/s as delineated by Japanese Industrial Standards …

jp (code pays fourni par la source)

Influence of interruption of oral mycophenolate mofetil for graft-versus-host disease prophylaxis on outcomes after single cord blood transplantation

Kahori Fukushi, Maki Monna‐Oiwa, Seiko Kato, Masamichi Isobe et autres

Mycophenolate mofetil (MMF), in combination with a calcineurin inhibitor, is used as the prophylaxis for graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT).Compared to intravenous methotrexate (MTX), MMF is associated with a lower incidence of mucositis and shorter time for hematopoietic …

jp (code pays fourni par la source)

Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study

Yohei Iimura, Mitsuko Nakazawa, Yukari Tsuru, Hitomi Togashi et autres

BACKGROUND: Although the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer support team (MCST) to facilitate cooperation across multidisciplinary medical staff in our hospital and established clinical evidence of supportive …

jp (code pays fourni par la source)

Effect of the Clean Bench Configuration Environment on Cleanliness during Intravenous Hyperalimentation Infusion Preparation

Seiichiro Kuroda, Anna Kiyomi, Shinobu Imai, Munetoshi Sugiura

When mixing and compounding injectable agents, performing aseptic manipulations on a clean bench maintained according to the requirements of the US Federal Standard Class 100 (≤100 pcs/ft3) is crucial for the prevention of contamination by airborne particulates or microbes. Owing to air …

Nigéria, jp (code pays fourni par la source)

Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study

Yohei Iimura, Mitsuko Nakazawa, Yukari Tsuru, Hitomi Togashi et autres

Abstract Background: Although the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer support team (MCST) to facilitate cooperation across multidisciplinary medical staff in our hospital and established clinical evidence of …

jp (code pays fourni par la source)

A Survey of Near-Miss Dispensing Errors in Hospital Pharmacies in Japan: DEPP-J Study—Multi-Center Prospective Observational Study—

Kenji Momo, Takeo Yasu, Seiichiro Kuroda, Sonoe Higashino et autres

The aim of this study was to determine the proportion of near-miss dispensing errors in hospital pharmacies in Japan. A prospective multi-center observational study was conducted between December 2018 and March 2019. The primary objective was to determine the proportion of near-miss …

jp (code pays fourni par la source)

Effects of raltegravir formulation change on medication adherence and medication errors

Sonoe Higashino, Takeo Yasu, Kenji Momo, Seiichiro Kuroda

This study was aimed at assessing the adherence and incorrect drug intake associated with changes in the dosing schedule of raltegravir, the first integrase strand transfer inhibitor, from 400 mg twice a day (BID) to 600 mg × 2 tablets once a …

jp (code pays fourni par la source)