Guirong Liang

A 2Tb 4b/Cell 6-Plane 3D-Flash Memory with 37.6Gb/mm 2 Bit Density and >85MB/s Write Throughput

Jayanth M. Thimmaiah, Ryuji Yamashita, In-Soo Yoon, Jason Li et autres

A 332-WL-layer stacked 2Tb 4b/Cell 6-plane 3D Flash memory achieves an areal density of$37.6 \text{Gb} / \text{mm}^{2}$. An 8 kB -physical and 16 kB -logical page architecture realizes a$<65 \mu \mathrm{s}$read latency and a$>85 \text{MB} / \mathrm{s}$program throughput. Write throughput is enhanced …

in, jp, us (code pays fourni par la source)

In situ-generated palladium nanoparticles promoted co-reduction of bromate and nitrate in hydrogenotrophic biofilms

Chengyang Wu, Guirong Liang, Siqing Xia, Jingzhou Zhou et autres

cn (code pays fourni par la source)

Machine learning-assisted multi-dimensional transcriptomic analysis of cytoskeleton-related molecules and their relationship with prognosis in hepatocellular carcinoma

Yuxuan Li, Mingbo Cao, Xiaoping Su, Gaoyuan Yang et autres

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, with a poor prognosis due to its aggressive nature and limited treatment options. Cytoskeletal dynamics play a critical role in tumor progression, but the prognostic and therapeutic potential of cytoskeleton-related genes …

cn (code pays fourni par la source)

Exosome-derived lnc-FAM72D-3 promotes lenvatinib resistance by remodeling hepatocellular carcinoma cytoskeleton via MBNL1/FAK axis

Yuxuan Li, Xiaoping Su, Yongchang Tang, Yupeng Ren et autres

cn (code pays fourni par la source)

Low Cost ‘On Pitch Select Gate’ (OPS) Technology for 3D Flash Memory

Amrit Prakash, Xiaochen Zhu, Guirong Liang, M. Higashitani et autres

Contrary to the general perception of 3D flash memory technology nodes being defined by the vertical stacking of word line layers, we, for the first time, present an unconventional approach employed in the mass production of BiCS FLASH™ generation 8 3D flash …

Single cell transcriptome profiling reveals pathogenesis of bullous pemphigoid

Guirong Liang, Chenjing Zhao, Wei Qin, Suying Feng et autres

Bullous pemphigoid (BP) triggers profound functional changes in both immune and non-immune cells in the skin and circulation, though the underlying mechanisms remain unclear. In this study, we conduct single-cell transcriptome analysis of lesional and non-lesional skin, as well as blood samples …

cn (code pays fourni par la source)

Dupilumab, corticosteroids and their combination for the treatment of bullous pemphigoid

Guirong Liang, Chao Sun, Hanmei Zhang, Zhiliang Li et autres

BACKGROUND: Conventional systemic corticosteroid therapy for bullous pemphigoid (BP) has been challenged due to severe adverse events. Dupilumab has emerged as an alternative therapeutical option of BP patients. OBJECTIVES: To evaluate the efficacy of dupilumab monotherapy and the combination with medium/low-dose corticosteroids …

cn (code pays fourni par la source)

Clinical and immunoserological characteristics of anti‐p200 pemphigoid: Comparisons of patients with epitope spreading and non‐epitope spreading

Y. Wang, Suo Li, Zhiliang Li, Ke Jing et autres

BACKGROUND: Anti-p200 pemphigoid is a rare autoimmune subepidermal blistering disease. Although the phenomenon of epitope spreading has been reported to be common in anti-p200 pemphigoid, the association between its clinical and immunoserological features has yet to be elucidated. OBJECTIVES: Our aim was …

cn (code pays fourni par la source)

Single cell transcriptome profiling reveals pathogenesis of Bullous Pemphigoid

Yetao Wang, Guirong Liang, Chenjing Zhao, Wei Qin et autres

Bullous Pemphigoid (BP) triggers profound functional changes in both non-immune and immune cells in the skin and circulation, yet the underlying mechanisms remain elusive. In this study, we conducted single-cell transcriptome analysis on donor-matched lesional and non-lesional skin, as well as blood …

cn, th (code pays fourni par la source)

Baricitinib as a novel treatment for bullous pemphigoid: a case series report

Guirong Liang, Xiaoguang Li, Hua Qian, Chao Sun et autres

Abstract Bullous pemphigoid (BP) is an autoimmune blistering disorder occurring mostly in the elderly. The standard treatment of BP patients with systemic corticosteroid have some potential serious side effects. Up till now, there is still lack of novel treatment for BP patients. …

cn, th (code pays fourni par la source)

IgE anti-BP180 NC16A autoantibody in both serum and blister fluid samples does not correlate with disease activity of bullous pemphigoid

Chao Sun, Hua Qian, Guirong Liang, Ruiyu Xiang et autres

The correlation between IgE anti-BP180 NC16A autoantibody and disease activity of bullous pemphigoid (BP) remains disputable. To determine the levels of IgE anti-BP180 NC16A autoantibody and its clinical significance in untreated BP patients. IgG and IgE anti-BP180 NC16A autoantibody in serum and …

cn (code pays fourni par la source)

Glucocorticoid receptor activation reprograms NK cells to drive AREG-mediated immunosuppression in skin cancer

Wei Qin, Guirong Liang, Rui Zeng, Yuancheng Li et autres

Summary Natural killer (NK) cells are potent mediators of anti-tumor immunity, yet their functions are frequently subverted by tumor microenvironment-driven immunosuppression. Here, we dissect the molecular mechanisms underlying NK cell dysfunction in cutaneous malignancies and identify a paradoxical cytokine shift in tumor-associated …

cn (code pays fourni par la source)