Accès ouvert
2026
article
OpenAlex
Salar Bakhtiyari, Iraj Alipourfard
Ischemic stroke represents a dynamic metabolic disorder of the neurovascular unit (NVU) rather than a static vascular occlusion followed by neuronal demise. Immediate oxygen and glucose deprivation rapidly deplete ATP, disrupt the transmembrane ionic gradients, increase glutamate excitotoxicity, and overload mitochondrial with …
us, pl
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Accès ouvert
2026
article
OpenAlex
Iraj Alipourfard, Zahra Shafaghat, Saber Saharkhiz, Marzieh Ramezani Farani et autres
Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment outcomes of patients with hematologic malignancies, including B-cell acute lymphoblastic leukemia (B-ALL), diffuse large B-cell lymphoma (DLBCL), and multiple myeloma (MM). However, issues such as antigen escape, T-cell exhaustion, and the limited …
pl, ir, ca, kr, us
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Accès ouvert
2025
article
OpenAlex
Seyedehfatemeh Ashabi, Elaheh Mavadat, Mahboubeh Moradalizadeh, Afshan Khoshnevis et autres
Triple-negative breast cancer (TNBC) signifies an enormous risk to women's health globally. TNBC is characterized by its aggressive nature, resistance to existing therapies, and poor prognosis. Understanding the molecular pathogenesis of breast cancer is crucial for identifying screening markers and therapeutic targets. …
ir, kr, us, pl
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Accès ouvert
2025
article
OpenAlex
Parinaz Parsi, Saber Saharkhiz, Marzieh Ramezani Farani, Salar Bakhtiyari et autres
Diabetes mellitus is a common and serious metabolic disease globally, characterized by increased blood glucose levels. The major pathogenesis is the functional impairment of insulin-producing beta cells in the pancreas and the lack of insulin secretion. Although both type 1 and type …
ir, ca, kr, us, pl
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Accès ouvert
2025
article
OpenAlex
Zahra Shafaghat, Safa Radmehr, Saber Saharkhiz, Amirhossein Khosrozadeh et autres
Non-coding RNAs (ncRNAs) are functional RNA molecules that do not code for proteins. Among these, circular RNAs (circRNAs) represent a recently identified class of endogenous ncRNAs with a pivotal role in gene regulation, alongside short ncRNAs (e.g., microRNAs or miRNAs) and long …
ir, ca, us, sa, kr, de, pl
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Accès ouvert
2024
article
OpenAlex
Zeinab Elyasi, Nasrin Ghiasi, Ali Salimi Khorshidi, Salar Bakhtiyari et autres
INTRODUCTION: Improving medication adherence plays a crucial role in preventing adverse complications of type 2 diabetes. OBJECTIVES: This study aimed to determine the effect of a health education program on knowledge, medication adherence, and HbA1c in rural patients with type 2 diabetes. …
ir
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Accès ouvert
2024
article
OpenAlex
Mehrnaz Mostafavi, Farhood Ghazi, Mahboobeh Mehrabifard, Vahid Alivirdiloo et autres
Radiotherapy (RT) is a gold standard cancer treatment worldwide. However, RT has limitations and many side effects. Nanoparticles (NPs) have exclusive properties that allow them to be used in cancer therapy. Consequently, the combination of NP and RT opens up a new …
ir, kr, pl
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Accès ouvert
2024
article
OpenAlex
Fatemeh Zarimeidani, Rahem Rahmati, Mehrnaz Mostafavi, Mohammad Darvishi et autres
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication and behavior, frequently accompanied by restricted and repetitive patterns of interests or activities. The gut microbiota has been implicated in the etiology of ASD due to its impact …
ir, us, pl
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Accès ouvert
2024
article
OpenAlex
Sepideh Chodary Khameneh, Sara Razi, Ramin Lashanizadegan, Sanaz Akbari et autres
The study of immunometabolism, which examines how immune cells regulate their metabolism to maintain optimal performance, has become an important area of focus in cancer immunology. Recent advancements in this field have highlighted the intricate connection between metabolism and immune cell function, …
ir, us
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Accès ouvert
2024
article
OpenAlex
Sara Rezaei, Salar Bakhtiyari, Khairolah Assadollahi, Somayeh Heidarizadi et autres
Introduction: The proteoglycans of the extracellular matrix increases in the glial scar during spinal cord injury and significantly affects the inhibition of axonal regeneration. Methods: The results of injury therapies are limited due to the lack of identifying a timely therapeutic intervention. …
ir
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Accès ouvert
2023
review
OpenAlex
Narges Jalilian, Reza Pakzad, Mahdi Shahbazi, Seyyed-Reza Edrisi et autres
Background. Cardiovascular diseases (CDs), notably coronary artery disease (CAD) due to atherosclerosis, impose substantial global health and economic burdens. Fatty acid-binding proteins (FABPs), including FABP-4, have been recently linked to CDs. This study conducted a systematic review and meta-analysis to examine FABP-4 …
ir, us
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2023
article
OpenAlex
Amin Bakhtiyari, Salar Bakhtiyari, Maryam Peymani, Karimeh Haghani et autres
Type 2 Diabetes Mellitus (T2DM) is known to cause dyslipidemia and increase the risk of cardiovascular disease (CVD). Fatty acid binding protein (FABP)-4 plays a significant role in various stages of T2DM and CVD. Although it has been demonstrated that genetic variations …
ir, us
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