Zahra Shafaghat

Cancer vaccines as targeted therapies: translational advances and challenges

Zahra Shafaghat, Maryam Sadri, Mona Roozbehani, Fatemeh Kheiri et autres

Cancer vaccines represent a promising class of immunotherapeutic agents with potential applications in cancer prevention and treatment. By eliciting tumor-specific immune responses, these vaccines may offer durable protection against tumor progression, recurrence, and metastasis while minimizing off-target toxicity associated with conventional therapies. …

ir (code pays fourni par la source)

HTLV-1 and ATL: Decoding Molecular Pathogenesis for Next-Generation Therapies

Mina Mohammad-Rezaei, Zahra Shafaghat, Mina Noroozbeygi, Mirza R. Baig et autres

ir, ae, iq, jo (code pays fourni par la source)

Collagen remodeling in breast cancer progression: from molecular mechanisms to diagnostic and therapeutic opportunities

Mina Mohammad-Rezaei, Zahra Shafaghat, Mina Noroozbeygi, Periyannan Velu et autres

ir (code pays fourni par la source)

Emerging Applications of CAR-T Cell Therapy in Overcoming Resistance and Expanding Targets in Hematologic Malignancies: Insights from Recent Research

Iraj Alipourfard, Zahra Shafaghat, Saber Saharkhiz, Marzieh Ramezani Farani et autres

Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment outcomes of patients with hematologic malignancies, including B-cell acute lymphoblastic leukemia (B-ALL), diffuse large B-cell lymphoma (DLBCL), and multiple myeloma (MM). However, issues such as antigen escape, T-cell exhaustion, and the limited …

pl, ir, ca, kr, us (code pays fourni par la source)

Circular RNAs in tumorigenesis: an insight into recent research in biogenesis and targeted tumor therapy

Zahra Shafaghat, Pezhman Golshanrad, Saber Saharkhiz, Anna Leśniak et autres

Circular RNAs (circRNAs) are eukaryotic RNA molecules that are covalently closed and have the characteristics of high stability, tissue-specific expression, and cell-specific expression. The majority of circRNAs are produced from pre-mRNAs that also result in linear RNA, and they have expression patterns …

ir, ca, pl, ge, kr (code pays fourni par la source)

Targeting cancer stem cells as the most aggressive and tumor-initiating cells

Maryam Sadri, Zahra Shafaghat, Mona Roozbehani, Maryam Dorfaki et autres

• Cancer stem cells (CSCs), as the most aggressive and tumor-initiating cells, play a fundamental role in driving key malignant behaviors in cancer. • CSCs exhibit low immunogenicity, enabling them to evade recognition and destruction by the immune system. CSCs also contribute …

ir, au, it (code pays fourni par la source)

Novel insights into possible ZnO nanoparticle-induced changes in key metabolic enzymes in HeLa cervical cancer cell line

R. Fallahi, Zahra Shafaghat, Sara Minaeian, Mohammad Taghi Goodarzi et autres

ir (code pays fourni par la source)

Circular RNA, A Molecule with Potential Chemistry and Applications in RNA-based Cancer Therapeutics: An Insight into Recent Advances

Zahra Shafaghat, Safa Radmehr, Saber Saharkhiz, Amirhossein Khosrozadeh et autres

Non-coding RNAs (ncRNAs) are functional RNA molecules that do not code for proteins. Among these, circular RNAs (circRNAs) represent a recently identified class of endogenous ncRNAs with a pivotal role in gene regulation, alongside short ncRNAs (e.g., microRNAs or miRNAs) and long …

ir, ca, us, sa, kr, de, pl (code pays fourni par la source)

Evaluation of CD73 , PD-1 , circHIPK3 , and circNRIP1 expression in the peripheral blood of patients with colorectal cancer

Zahra Shafaghat, Ali Arash Anoushirvani, Mehdi Nikkhah, Fatemeh Rahbari solute et autres

INTRODUCTION: Colorectal cancer (CRC) is known to have an association with circular RNAs (circRNAs) and immune checkpoint factors. This study sought to examine the expression levels of hsa_circ_0000284 and hsa_circ_0004771 molecules and the programmed cell death 1 protein (PD-1) and ecto-5'-nucleotidase (CD73) …

ir, it, at (code pays fourni par la source)

Effects of Probiotics on Liver Diseases: Current In Vitro and In Vivo Studies

Maryam Sadri, Zahra Shafaghat, Mona Roozbehani, Akram Hoseinzadeh et autres

ir (code pays fourni par la source)

Phytohormone-induced changes in growth, physiology, and biochemistry of Aurantiochytrium sp. for sustainable bioproduction

Zahra Shafaghat, Farzaneh Najafi, R. A. Khavari-Nejad, Mehdi Mohammadi et autres

ir (code pays fourni par la source)

Growth dynamics and lipid metabolism of Aurantiochytrium sp.: insights into its potential applications

Zahra Shafaghat, Farzaneh Najafi, R. A. Khavari-Nejad, Mehdi Mohammadi et autres

ir (code pays fourni par la source)