Maryam Peymani

Unveiling Prognostic Biomarker in Colorectal Cancer: ADH6 and BDH1 through Oxidoreductase Gene Family Dysregulation

Fatemeh Kaviani, Samaneh Dalali, Mohammad Mahdevar, Andisheh Oroujalian et autres

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Identification of RNA binding proteins targeting TP53, RB1 and PTEN in colorectal cancer as potential biomarkers for diagnosis, drug resistance, sensitivity and prognosis

Ava Asadi, Mehrdad Hashemi, Maryam Peymani, Najmeh Ranji et autres

Colorectal cancer (CRC) is a prevalent gastrointestinal malignancy with high incidence and mortality. Dysregulated RNA-binding proteins (RBPs) have been implicated in various cancers, yet their role in regulating tumor suppressors in CRC is underexplored. This study analyzed TCGA gene expression data to …

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Identification of lncRNA LINC02747 as a Novel Potential Biomarker for Breast Cancer

Mandana Kazemi, Maryam Peymani, Mehrdad Behmanesh, Razieh Ghasemi

Background and purpose: Breast cancer (BC) is the leading cause of cancer-related mortality among women worldwide. Consequently, the early identification of breast cancer is crucial for improving patient survival, and biomarkers represent promising tools for achieving this objective. This study aims to …

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Pseudogene expression as predictors of survival in colorectal cancer: Focus on CCT6P1 and SMPD4BP

Fatemeh Habibi, Mohammad Mahdevar, Andisheh Oroujalian, Maryam Peymani

Colorectal cancer (CRC) is a highly prevalent form of cancer, and molecular studies show that differential gene expression is strongly linked to its progression. Evidence confirmed the significant impact of pseudogenes in the development of various cancers. This study aimed to analyse …

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Lapatinib-Loaded Glucose-Functionalized Silver Nanoparticles Enhance Efficacy in HER2-Positive Breast Cancer Cells and Modulate Survival-Associated Genes

Behnaz Dolatabadi, Maryam Peymani, Mehrdad Hashemi, Leila Rouhi et autres

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Cloning of eSpCas9(1.1) GFP vector with improved specificity using in CRISPR/Cas9 system

Firouzeh Morshedzadeh, Samaneh Sharif, Maryam Peymani, Mohammad Reza Abbaszadegan

ویرایش ژن به مجموعه‌ای از فناوری‌ها اطلاق می‌شود که به پژوهشگران امکان تغییر و دست‌کاری توالی DNA را در سلول‌ها می‌دهد و می‌تواند منجر به اضافه‌کردن، حذف یا اصلاح مواد ژنتیکی در نواحی خاصی از ژنوم شود. فناوری CRISPR/Cas9 به‌عنوان یکی از …

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TMEM105 upregulation promotes colorectal cancer malignancy: a novel prognostic biomarker potentially linked to the MYC-Ribosome biogenesis axis

Ahmad Rezaenasab, Seyed Jalal Zargar, Maryam Peymani, Kamran Ghaedi

Transmembrane protein 105 (TMEM105 ) has recently emerged as a potential oncogenic factor in various malignancies, yet its role in colorectal cancer (CRC) remains unclear. In this study, we comprehensively investigated the expression and function of TMEM105 in CRC through an integrated …

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List of contributors

Navid Abedpoor, Mazaher Ahmadi, Abdolamir Allameh, Mina Allameh et autres

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Efficiency of all-trans retinoic acid on gastric cancer

Maral Hajipour, Khatere Mokhtari, Maryam Peymani

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Phytochemical in the treatment of multidrug-resistance cancer

Andisheh Oroujalian, Amirmohammad Rabiei, Maryam Peymani

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List of contributors

Navid Abedpoor, Ebrahim Alinia-Ahandani, Shadi Askari, Britny Blaize et autres

Allele-specific disruption of KRAS p.G12V in colorectal cancer cells using electroporated Cas9 RNPs.

Firouzeh Morshedzadeh, Samaneh Sharif, Maryam Peymani, Malihe Lotfi et autres

Objectives: Colorectal cancer (CRC) is a major cause of mortality, and KRAS mutations drive tumorigenesis and therapy resistance. Although CRISPR-Cas9 enables precise genome editing, intracellular delivery of Cas9 ribonucleoproteins (RNPs) remains challenging. We evaluated direct electroporation of Cas9-sgRNA RNPs targeting KRAS p.G12V …

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