Sirikan Limpakan Yamada

VEGF-A Gene Expression Profiling in Northern Thai Gastric Cancer Patients and Potential for Anti-VEGF Therapy

Amonnat Sukhamwang, Hathairat Thananchai, Peticha Tanprasert, Pornngarm Limtrakul et autres

Background/Objectives: Gastric cancer (GC) remains a major burden in Northern Thailand. Elevated interleukin-8 (IL-8) and vascular endothelial growth factor A (VEGF-A) expression are linked with poor prognosis and tumor progression in gastric cancer. However, the concordance of VEGF-A and IL-8 gene expression …

th (code pays fourni par la source)

VEGF-A Gene Expression Profiling in Northern Thai Gastric Cancer Patients and Potential for Anti-VEGF Therapy

Amonnat Sukhamwang, Hathairat Thananchai, Peticha Tanprasert, Pornngarm Limtrakul et autres

Background/Objectives: Gastric cancer (GC) remains a major health burden in Northern Thailand. Elevated expression of interleukin-8 (IL-8) and vascular endothelial growth factor A (VEGF-A) is often associated with poor prognosis and tumor progression in gastric cancer. However, the concurrent expression of VEGF-A …

Survival benefit of conversion surgery after intravenous 5-fluorouracil-based chemotherapy in unresectable advanced gastric cancer: a retrospective cohort study

Peticha Tanprasert, Bandhuphat Chakrabandhu, Supachai Yodkeeree, Pornngarm Limtrakul et autres

BACKGROUND: Systemic chemotherapy may relieve symptoms and induce tumor downstaging in patients with unresectable gastric cancer. However, the survival benefit of primary tumor resection after chemotherapy remains unclear. This study aimed to determine the survival outcomes of conversion surgery in patients with …

th (code pays fourni par la source)

Collagen Deposition and Inflammatory Response Associated with Macroporous Mesh Shrinkage in Incisional Hernia Repair: A Rat Model

Peticha Tanprasert, Kanokkan Tepmalai, Bandhuphat Chakrabandhu, Supachai Yodkeeree et autres

Background: Mesh repair is the current recommendation for the treatment of incisional hernia; however, the best mesh has yet to be determined. The objective of this study was to compare the inflammatory response and collagen deposition in primary incisional hernia repair (P) …

th (code pays fourni par la source)

Association of DNA Repair and Drug Transporter in Relation to Chemosensitivity in Primary Culture of Thai Gastric Cancer Patients

Pattama Wongsirisin, Sirikan Limpakan Yamada, Supachai Yodkeeree, Wanisa Punfa et autres

Acquired resistance is a major reason for poor clinical outcomes in cancer chemotherapy patients. The aim of this study was to determine the sensitivity to anticancer drugs and to identify the alterations of DNA repair and drug transporter in a model of …

th (code pays fourni par la source)

Abstract 1815: Bystander effect and genomic instability in human cells and their progeny after irradiation with X rays, protons or carbon ions: role of gap junction communication

Narongchai Autsavapromporn, Ianik Plante, Cui Hua Liu, Teruaki Konishi et autres

Abstract Purpose: Ionizing Radiation (IR)-induced bystander effects and genomic instability have important implication in radiotherapy and radioprotection. Their persistence in the progeny of normal cells may contribute to risk of long-term radiation-related health effect in human, including cancer. Hence, this study investigates …

th, us, jp (code pays fourni par la source)

Abstract 4257: The survival prediction after curative resection with adjuvant chemotherapy and neo-adjuvant chemotherapy in locally advance stage by gastric mucosal IL-8 mRNA expression for Thai gastric cancer

Sirikan Limpakan Yamada

Abstract Background: Unlike Japanese gastric cancer, the majority type of Thai gastric cancer caused poor prognosis; especially poorly differentiated, signet ring cell histologic type that is predominant in nearly 70 percent of gastric cancer population. The detection of high mRNA IL-8 expression …

th (code pays fourni par la source)

Validation of the Diagnostic Score for Acute Lower Abdominal Pain in Women of Reproductive Age

Kijja Jearwattanakanok, Sirikan Limpakan Yamada, Watcharin Suntornlimsiri, Waratsuda Smuthtai et autres

Background. The differential diagnoses of acute appendicitis obstetrics, and gynecological conditions (OB-GYNc) or nonspecific abdominal pain in young adult females with lower abdominal pain are clinically challenging. The present study aimed to validate the recently developed clinical score for the diagnosis of …

th (code pays fourni par la source)

Clinical Indicators for Differential Diagnosis of Acute Lower Abdominal Pain in Women of Reproductive Age

Kijja Jearwattanakanok, Sirikan Limpakan Yamada, Watcharin Suntornlimsiri, Waratsuda Smuthtai et autres

Background: Acute lower abdominal pain in women of reproductive age is a challenging condition for clinical diagnosis. Computerized tomography yields high accuracy, but may not be cost-effective in low-middle income countries. Selective diagnostic approach based on clinical findings may be more appropriate. …

th (code pays fourni par la source)

Predominant mucosalIL-8mRNA expression in non-cagAThais is risk for gastric cancer

Sirikan Limpakan Yamada, Shunji Kato, Takeshi Matsuhisa, Luksana Makonkawkeyoon et autres

AIM: To study gastric mucosal interleukine-8 (IL-8) mRNA expression, the cytotoxin-associated gene A (cagA) mutation, and serum pepsinogen (PG) I/II ratio related risk in Thai gastric cancer. METHODS: There were consent 134 Thai non-cancer volunteers who underwent endoscopic narrow band imaging examination, …

th, jp (code pays fourni par la source)

Abstract 1148: The factual evidence of gastric mucosal IL-8 mRNA expression, cagA gene H.pylori infection, and pepsinogen I/II ratio in Thai gastric cancer .

Sirikan Limpakan Yamada, Shunji Kato, Takeshi Matsuhisa, Luksana Makonkawkeyoon et autres

Abstract Background: Interleukine-8 (IL-8) gene expression was reported in vitro that it may relate to cagA gene in Japanese. There is no in vivo study demonstrated how its level related to cagA genotype and serum pepsinogen I/II ratio in other Asian Ethnic …

th, jp (code pays fourni par la source)

Clinical Scoring for Diagnosis of Acute Lower Abdominal Pain in Female of Reproductive Age

Kijja Jearwattanakanok, Sirikan Limpakan Yamada, Watcharin Suntornlimsiri, Waratsuda Smuthtai et autres

Background. Obstetrics and gynecological conditions (OB-GYNc) are difficult to be differentiated from appendicitis in young adult females presenting with acute lower abdominal pain. Timely and correct diagnosis is clinically challenging. Method. A retrospective data analysis was performed on 542 female patients who …

th (code pays fourni par la source)