Yi Xia

A shape-constrained arc-length reformulation for sequential convex programming in hypersonic reentry trajectory optimization

Yi Xia, Yang Zhao, Yeguang Wang, Shipeng Wang et autres

cn (code pays fourni par la source)

Disturbance-tolerant bidirectional transition control for quadplane VTOL aircraft using unified parameters via reference shaping and trim mapping

Yi Xia, Naiming Qi, Bo Qi, Xiyan Zhao et autres

cn (code pays fourni par la source)

Correction to “Novel Triazole Ribonucleoside Down-Regulates Heat Shock Protein 27 and Induces Potent Anticancer Activity on Drug-Resistant Pancreatic Cancer”

Yi Xia, Yang Liu, Jinqiao Wan, Menghua Wang et autres

Correction to “Discovery of Novel Arylethynyltriazole Ribonucleosides with Selective and Effective Antiviral and Antiproliferative Activity”

Jinqiao Wan, Yi Xia, Yang Liu, Menghua Wang et autres

status: Published

Investigations of size effects of heterogeneous architected metamaterials

Yi Xia, Zengbo Xu, Hua Shu Yang, Wei Fan et autres

cn, gb, de (code pays fourni par la source)

The mitochondrial catastrophe induced by NUPR1 inhibitors as a novel strategy to fight against cancer

Juan Iovanna, Jose Luis Hernandez Neira, Olga Abián, Adrián Velázquez‐Campoy et autres

fr, ar, es, cn, it, us (code pays fourni par la source)

Mechanisms of induced resistance to the antitumoral agent ZZW-115 in pancreas ductal adenocarcinoma

Patricia Santofimia‐Castaño, Wenjun Lan, Matías Estarás, Yi Xia et autres

Drug resistance remains a major obstacle in treating pancreatic ductal adenocarcinoma (PDAC). Nuclear protein 1 (NUPR1), a stress-responsive protein implicated in cancer progression and treatment resistance, represents a potential therapeutic target. Our laboratory has developed NUPR1 inhibitors such as ZZW-115. In this …

fr, cn, ar (code pays fourni par la source)

Self-assembling dendrimer nanodrug formulations for decreased hERG-related toxicity and enhanced therapeutic efficacy

Dinesh M. Dhumal, Patricia Santofimia‐Castaño, Juan Liu, Marion Casanova et autres

Cardiotoxicity, especially human ether-a-go-go-related gene (hERG)-related toxicity, is a leading cause of drug failure or market withdrawal. Reducing hERG binding to obviate potential cardiac toxicity is crucial. Nanotechnology has been applied to drug delivery for reducing drug toxicity and improving efficacy, but …

fr, cn (code pays fourni par la source)

Design of quasi-zero-stiffness metamaterials with ultra-wideband vibration isolation performance

Lingbo Li, Fan Yang, Sanfeng Liu, Zhengmiao Guo et autres

cn (code pays fourni par la source)

Mechanisms of induced resistance to the antitumoral agent ZZW-115 in pancreas ductal adenocarcinoma

Patricia Santofimia‐Castaño, Wenjun Lan, Matias Estares, Yi Xia et autres

fr, cn, ar (code pays fourni par la source)

Bola-amphiphilic glycodendrimers for targeting glial cells in the brain

Zhancun Bian, Tom Roussel, Erik Laurini, Marc Maresca et autres

a click reaction using unprotected carbohydrate building units, and self-assembled into small and spherical nanoparticles by virtue of their amphiphilicity. In a mouse model, both dendrimer nanoparticles successfully reached the brain following IN administration, where the glucose-dendrimer Ia selectively targeted astrocytes and …

fr, cn, it, pl (code pays fourni par la source)

Development of an efficient NUPR1 inhibitor with anticancer activity

Xi Liu, Ana Jiménez-Alesanco, Z Li, Bruno Rizzuti et autres

Pancreatic cancer is highly lethal and has limited treatment options available. Our team had previously developed ZZW-115, a promising drug candidate that targets the nuclear protein 1 (NUPR1), which is involved in pancreatic cancer development and progression. However, clinical translation of ZZW-115 …

fr, es, cn, it, ar (code pays fourni par la source)