Chenlan Xia

Lacticaseibacillus rhamnosus -Derived Extracellular Vesicles Alleviate Colitis via PPAR Signaling and the Gut Microbiota–Metabolite Axis

Yingjie Huang, La Xi, Bin Yu, Zihao Zhang et autres

Abstract Intestinal barrier dysfunction is a hallmark of inflammatory bowel disease (IBD), yet effective therapies remain limited, and the mechanisms of probiotic-derived extracellular vesicles (EVs) are poorly understood. Using complementary cell, murine, and intestinal organoid models, we investigated the protective effects of …

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Ultrasound-Assisted Salt Penetration in Sauced Duck: Insights from LF-NMR and MRI Combined Analysis

Xiangyu Wang, Chenlan Xia, Huimin Li, Yangying Sun et autres

This study investigated the effect of ultrasound-assisted curing on salt penetration in sauced duck using a combination of low-field nuclear magnetic resonance (LF-NMR) and magnetic resonance imaging (MRI). Ultrasound treatment significantly accelerated salt penetration in duck meat during curing. The salt content …

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Unveiling the mechanism of Latilactobacillus sakei LZ217 cell-free supernatant against Helicobacter pylori through metabolomics and network pharmacology

Chenlan Xia, Qingqing Zhou, Xia Meng, Ziqi Chen et autres

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Lactic acid bacteria target NF-κB signaling to alleviate gastric inflammation

Shiying Wu, Yuenuo Luo, Fangtong Wei, Yanan Li et autres

L. plantarum ZJ316 treatment attenuated H. pylori -induced inflammation by suppressing NF-κB signaling and promoting beneficial changes in the gastric microbiota composition.

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Metabolism of quercitrin in the colon and its beneficial regulatory effects on gut microbiota

Xia Meng, Chenlan Xia, Hongchen Wu, Qing Gu et autres

BACKGROUND: Quercitrin is a dietary flavonoid widely found in plants with various physiological activities. However, whether quercitrin alters gut microbiota in vivo is not well understood. The aim of this study was to investigate metabolism of quercitrin in the colon and its …

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Effects of Latilactobacillus sakei LZ217 on Gastric Mucosal Colonization, Metabolic Interference, and Urease Expression in Helicobacter pylori Infection

Chenlan Xia, Ziqi Chen, Yongqiang Chen, Fangtong Wei et autres

Emerging evidence suggests differential antagonism of lactic acid-producing bacteria (LAB) to Helicobacter pylori, posing challenges to human health and food safety due to unclear mechanisms. This study assessed 21 LAB strains from various sources on H. pylori growth, urease activity, and coaggregation. …

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Soluble Dietary Fiber from Citrus unshiu Peel Promotes Antioxidant Activity in Oxidative Stress Mice and Regulates Intestinal Microecology

Mengqi Fu, Xin Gao, Zuorui Xie, Chenlan Xia et autres

Aging is characterized by the progressive degeneration of bodily tissues and decline in physiological functions, a process that may be exacerbated by imbalances in intestinal flora. Soluble dietary fiber (PSDF) from Citrus unshiu peel has demonstrated strong free radical scavenging ability to …

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Role of folic acid in regulating gut microbiota and short-chain fatty acids based on an in vitro fermentation model

Xiaogu Zheng, Chenlan Xia, Manman Liu, Hongchen Wu et autres

Folic acid deficiency is common worldwide and is linked to an imbalance in gut microbiota. However, based on model animals used to study the utilization of folic acid by gut microbes, there are challenges of reproducibility and individual differences. In this study, …

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Lactiplantibacillus plantarum ZJ316 Reduces Helicobacter pylori Adhesion and Inflammation by Inhibiting the Expression of Adhesin and Urease Genes

Shiying Wu, Yang Xu, Ziqi Chen, Yongqiang Chen et autres

SCOPE: The present study aims to investigate the anti-Helicobacter pylori (H. pylori) effects of Lactiplantibacillus plantarum ZJ316 (L. plantarum ZJ316) both in vitro and in vivo. METHODS AND RESULTS: This study finds that L. plantarum ZJ316 effectively suppresses H. pylori adhesion in …

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Lactiplantibacillus plantarum ZJ316–fermented milk ameliorates dextran sulfate sodium–induced chronic colitis by improving the inflammatory response and regulating intestinal microbiota

Qing Gu, Ziqi Chen, Nana Liu, Chenlan Xia et autres

The pathogenesis of inflammatory bowel disease may be related to local inflammatory damage and disturbances in intestinal microecology. Probiotic therapy is a safe and effective therapeutic approach. Considering that fermented milk is accepted and enjoyed by many people as a daily dietary …

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The joint effects of ultrasound and modified atmosphere packaging on the storage of sauced ducks

Tingting Mao, Chenlan Xia, Tao Zeng, Qiang Xia et autres

Due to the inferior shelf life of meat products without undergoing autoclaving treatment and the limitation of a single preservation technique, the joint effects of ultrasound and modified atmosphere packaging (MAP) on the cold storage of sauced ducks at 4 °C were …

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Lactobacillus plantarum ZJ316 alleviates ulcerative colitis by inhibiting inflammation and regulating short-chain fatty acid levels and the gut microbiota in a mouse model

Qing Gu, Chenlan Xia, Nana Liu, Ziqi Chen et autres

Our study suggested that ZJ316 could be used to relieve ulcerative colitis (UC) as dietary therapeutics.

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