Yajuan Qin

ZL006-05 prevents tPA-induced haemorrhagic transformation after stroke via inhibiting neutrophil myeloperoxidase-related pathway

Wei Chen, H W Wu, Xiumei Xu, Yajuan Qin et autres

Background Haemorrhagic transformation (HT) is the most feared complication of thrombolytic therapy in acute ischaemic stroke (AIS). This study aims to determine whether bornyl-2-hydroxy-4-(2-hydroxy-3,5-dichlorobenzyl) aminobenzoate (ZL006-05), a neuroprotectant that mitigates cerebral ischaemia/reperfusion injuries in animals and improves functional outcome in AIS patients, …

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Optimal overtaking trajectory planning for intelligent vehicles considering blind-spot pedestrian position uncertainty

Yajuan Qin, Chunyan Wang, Wanzhong Zhao, Boyang Yu et autres

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Multi-perspective investigation of the effects and interaction mechanisms of three common dietary fiber on cassava starch properties

Guojun Lv, Yihong Bao, Yajuan Qin, Bo Li et autres

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Type 3 resistant starch prepared from euryale ferox alleviated the obesity symptoms via gut microbiota regulation

Yutong Zhang, Jiayi Huang, Yajuan Qin, Xiaoai Chen et autres

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Effects of methoxy groups and carbon–carbon double bonds in phenolic acids on the physicochemical characteristics and digestibility of cassava starch

Guojun Lv, Dehai Li, Yihong Bao, Yajuan Qin et autres

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Novel Hypochlorous Acid-Activated Near-Infrared Probe Monitors the Dynamic Changes of Myeloperoxidase Activity in Ischemic Brain

Meiling Sun, Yuting Wang, Huijun Xu, Yuting Shen et autres

Myeloperoxidase (MPO) contributes to the progression of ischemic damage. To fully understand MPO biology, highly sensitive and specific probes that can trace the activity of endogenous MPO fluxes are indispensable. Here, we developed two hypochlorous acid (HClO)-activated near-infrared probes to image MPO …

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The interaction between banana polyphenols and starch improves the bioavailability of polyphenols after non-co-heating complexation

Yajuan Qin, Jingfeng Ran, Xiaoai Chen, Xuan Zhang et autres

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Monomeric or Homodimer Conjugates of Fibroblast Activation Protein Inhibitor and Cyanine 7 Bearing a Meso-Chloride as Near-Infrared Fluorescence Probes: Design, Synthesis, and Comparative In Vivo Imaging of Distinct Breast Cancer Subtypes

Panpan Chen, Zhipeng Lu, Xiaowei Feng, Yan Hu et autres

Intraoperative fluorescence navigation can illuminate the tumor, directing surgeons to accurately achieve negative margins, which not only reduces recurrence but also minimizes the incidence of complications. Herein, we developed two near-infrared fluorescent probes FAPI-Cy7-Cl (Em max = 820 nm) and (FAPI) 2 …

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Effects of Methoxy Groups and Carbon–Carbon Double Bonds in Phenolic Acids on the Physicochemical Characteristics and Digestibility of Cassava Starch

Guojun Lv, Dehai Li, Yihong Bao, Yajuan Qin et autres

Pectin enhances the inhibition of α-amylase via the mixture of rutin and quercetin

Yajuan Qin, Xiaoai Chen, Fei Xu, Kexue Zhu et autres

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Disrupting stroke-induced GAT-1-syntaxin1A interaction promotes functional recovery after stroke

Yu‐Hui Lin, Feng Wu, Tingyou Li, Fan Gao et autres

Although stroke is a frequent cause of permanent disability, our ability to promote stroke recovery is limited. Here, we design a small-molecule stroke recovery promoting agent that works by dissociating γ-aminobutyric acid (GABA) transporter 1 (GAT-1) from syntaxin1A (Synt1A), a soluble N-ethylmaleimide-sensitive …

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Synergistic effect of pectin and the flavanols mixture on in vitro starch digestion and the corresponding mechanism

Yajuan Qin, Yutong Zhang, Xiaoai Chen, Fei Xu et autres

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