Walid Albanna

Treatment challenges of ruptured intracranial aneurysms during pregnancy: A case record and review of the literature

Christian Blume, Christian Mayer, Matthias Simon, Walid Albanna et autres

Introduction: Aneurysmal subarachnoid hemorrhage (aSAH) during pregnancy is a rare but serious complication associated with significant maternal and fetal morbidity and mortality. Due to a limited number of published cases, development of guidelines for the management of aSAH in pregnant women has …

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Intra-arterial nimodipine for the treatment of refractory delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage

Laura Victoria Vossen, Miriam Weiss, Walid Albanna, Catharina Conzen et autres

BACKGROUND: Delayed cerebral ischemia (DCI) is one of the main contributors to poor clinical outcome after aneurysmal subarachnoid hemorrhage (SAH). Endovascular spasmolysis with intra-arterial nimodipine (IAN) may resolve angiographic vasospasm, but its effect on infarct prevention and clinical outcome is still unclear. …

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The oxygen reactivity index indicates disturbed local perfusion regulation after aneurysmal subarachnoid hemorrhage: an observational cohort study

Nick Kastenholz, Murad Megjhani, Catharina Conzen, Walid Albanna et autres

Abstract Background Cerebral autoregulation (CA) can be impaired in patients with delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). The Pressure Reactivity Index (PRx, correlation of blood pressure and intracranial pressure) and Oxygen Reactivity Index (ORx, correlation of cerebral perfusion pressure …

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Generation of iPSC-derived human forebrain organoids assembling bilateral eye primordia

Elke Gabriel, Walid Albanna, Giovanni Pasquini, Anand Ramani et autres

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Opening a window to the acutely injured brain: Simultaneous retinal and cerebral vascular monitoring in rats

Laura Warner, Annika Bach-Hagemann, Tobias Philip Schmidt, Sarah Pinkernell et autres

Many recent research projects have described typical chronic changes in the retinal vasculature for diverse neurovascular and neurodegenerative disorders such as stroke or Alzheimer's disease. Unlike cerebral vasculature, retinal blood vessels can be assessed non-invasively by retinal vessel analysis. To date, there …

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Elevated concentrations of macrophage migration inhibitory factor in serum and cerebral microdialysate are associated with delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage

Felix Neumaier, Christian Stoppe, Anzhela Stoykova, Miriam Weiss et autres

Objective Inflammation is increasingly recognized to be involved in the pathophysiology of aneurysmal subarachnoid hemorrhage (aSAH) and may increase the susceptibility to delayed cerebral ischemia (DCI). Macrophage migration inhibitory factor (MIF) has been shown to be elevated in serum and cerebrospinal fluid …

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Endovascular treatment for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage – a retrospective cohort analysis

Michael Veldeman, Laura E. Vossen, Miriam Weiss, Walid Albanna et autres

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Optimal Cerebral Perfusion Pressure and Brain Tissue Oxygen in Aneurysmal Subarachnoid Hemorrhage

Murad Megjhani, Miriam Weiss, Jenna L. Ford, Kalijah Terilli et autres

Background: Targeting a cerebral perfusion pressure optimal for cerebral autoregulation (CPPopt) has been gaining more attention to prevent secondary damage after acute neurological injury. Brain tissue oxygenation (PbtO 2 ) can identify insufficient cerebral blood flow and secondary brain injury. Defining the …

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Revisiting the Timeline of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage: Toward a Temporal Risk Profile

Tobias Philip Schmidt, Miriam Weiss, Anke Hoellig, Omid Nikoubashman et autres

BACKGROUND: Delayed cerebral ischemia (DCI) is one of the main determinants of clinical outcome after aneurysmal subarachnoid hemorrhage (SAH). The classical description of risk for DCI over time is currently based on the outdated concept of angiographic vasospasm. The goal of this …

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Intraarterial Nimodipine Versus Induced Hypertension for Delayed Cerebral Ischemia: A Modified Treatment Protocol

Miriam Weiss, Walid Albanna, Catharina Conzen, Nick Kastenholz et autres

Background: Rescue treatment for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage can include induced hypertension (iHTN) and, in refractory cases, endovascular approaches, of which selective, continuous intraarterial nimodipine (IAN) is one variant. The combination of iHTN and IAN can dramatically increase vasopressor …

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Risk Factors for Cerebral Vasospasm in Patients with Aneurysmal Subarachnoid Hemorrhage: A Tertiary Care Center Experience

Muhammad Mohsin Khan, Nissar Shaikh, Zohaib Yousaf, Hussain Sultan et autres

Abstract Objectives Cerebral vasospasm in subarachnoid hemorrhage (SAH) is associated with high morbidity and mortality. There is a lack of consensus on the risk factors leading to cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH). In this retrospective study, our objective …

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Decompressive hemicraniectomy after aneurysmal subarachnoid hemorrhage—justifiable in light of long-term outcome?

Michael Veldeman, Miriam Weiss, Lorina Daleiden, Walid Albanna et autres

PURPOSE: Decompressive hemicraniectomy (DHC) is a potentially lifesaving procedure in refractory intracranial hypertension, which can prevent death from brainstem herniation but may cause survival in a disabled state. The spectrum of indications is expanding, and we present long-term results in a series …

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