Yan Hong Zhou

Long non-coding RNA SNHG6 promotes odontoblastic differentiation of human dental pulp stem cells via the PI3K/Akt/mTOR pathway

Yan Hong Zhou, Lin Ye, Chen Yu Huang, Yao Wang

cn (code pays fourni par la source)

Molecular basis of high-torque transmission of the Vibrio polar flagellar motor

Ling Zhang, Jiaxing Tan, Xiaofei Wang, Michio Homma et autres

Abstract The bacterial flagellar motors are huge protein nanomachines that drive rotation of the flagellum for bacterial motility, and have considerable diversity in structure among bacterial species, which enables the transmission of different torques to the flagellar filaments to propel bacteria and …

cn, jp (code pays fourni par la source)

The alterations of the synthetic pathway and metabolic flux of auxin indole-3-acetic acid govern thermotolerance in Lentinula edodes mycelia subjected to heat stress

Jiaxin Song, Jiayue Chen, Yang Xiao, Yan Hong Zhou et autres

ABSTRACT Heat stress poses a significant constraint on the annual production of Lentinula edodes (L. edodes ), a challenge that has been intensified by global warming. Previous studies have established a close relationship between intracellular indole-3-acetic acid (IAA) content and heat tolerance …

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Single-cell multi-omics analysis reveals cellular subpopulations associated with relapse in high-risk B-ALL following intensified chemotherapy

Li Liu, Xiaoyan Mao, Chunhui Yang, Na Li et autres

Introduction: Acute lymphoblastic leukemia (ALL) is the most prevalent malignant tumor in children, with B-cell ALL (B-ALL) accounting for 85% of cases. Despite advancements in chemotherapy and supportive care, a subset of high-risk B-ALL patients still experience relapse post-treatment. The molecular mechanisms …

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Enhancement of postharvest longan fruit quality through chitosan (CTS)-induced modulation of energy and proline metabolism

Xinmin Lv, Yulian Li, Jiaying Chen, Shilian Huang et autres

Abstract Chitosan (CTS), a biologically safe preservative, is crucial for post-harvest treatment of fruit and vegetables, yet its regulatory mechanisms remain poorly understood. Our research on various CTS concentrations in longan fruit post-harvest showed that 1.5% CTS curtailed Weight loss and malondialdehyde …

cn, ca (code pays fourni par la source)

P30-54 Building an quantitative AOP for developmental neurotoxicity using prediction modeling along with in vitro data: A case study for bisphenol S

Mei Ni, Devara Sandhya Deepika, Yan Hong Zhou, M Kellis et autres

cn, es (code pays fourni par la source)

Mechanisms of SNP and melatonin effects on antioxidant and chlorophyll metabolism in postharvest okra

Xianjun Chen, Yao Jiang, Jianwei Zhang, Xiaocheng Liu et autres

Abstract Okra fruit rapidly undergoes chemical deterioration after harvest, necessitating effective preservation strategies. This study represents the first comprehensive investigation combining transcriptomic analysis with biochemical assessment to elucidate how SNPs and MT affect antioxidant capacity and chlorophyll metabolism in okra. MT + …

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Identification of novel hub genes and pathways predictive of fibrosis progression in cancer-related lymphedema through integrated multi-omics

Junzhe Chen, Yunpeng Chen, Liangliang Wang, Yaping Deng et autres

Background: Cancer-related lymphedema (CRL) is a common chronic complication following cancer treatment, characterized by impaired lymphatic drainage, interstitial fluid retention, and progressive fibrosis. Although the mechanisms of hypertrophic scar (HTS) fibrosis have been extensively investigated, the molecular drivers of fibrosis in CRL …

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Biochemical and transcriptomic analyses reveal the mechanisms underlying SNP and melatonin effects on antioxidant capacity and chlorophyll metabolism in postharvest okra

Xianjun Chen, Yao Jiang, Jianwei Zhang, Xiaocheng Liu et autres

cn (code pays fourni par la source)

Exploring the Plasma Proteome: Identifying Hub Proteins linking Aging, Homeostasis, and Organ Function

Juan Jiao, Fei Gao, Hong‐Ye Zhao, Mingjun Jiang et autres

As effectors of interactions between genes and the environment, plasma proteins can monitor homeostasis and reflect the aging state of an organism. However, biomarkers of aging that are associated with homeostasis are still unclear. This study investigates the phenotype-related plasma proteome profiles …

cn (code pays fourni par la source)

ZAR1/2‐Regulated Epigenetic Modifications are Essential for Age‐Associated Oocyte Quality Maintenance and Zygotic Activation

Yuke Wu, Yingyan Chen, Qing Liu, Leilei Ai et autres

The developmental competence and epigenetic progression of oocytes gradually become dysregulated with increasing maternal age. However, the mechanisms underlying age-related epigenetic regulation in oocytes remain poorly understood. Zygote arrest proteins 1 and 2 (ZAR1/2) are two maternal factors with partially redundant roles …

cn (code pays fourni par la source)

Chromosome-Scale Genome Assemblies and Population Re-Sequence of the Mango Tilapia Provide Insights into the Adaptive Evolution

Ying Lu, Liming Luo, Kun Zhou, Yan Hong Zhou et autres