Kun Zhou

A chromosome-level genome assembly and multi-omics analyses provide insights into the molecular basis of low-temperature tolerance in Coptodon zillii

Liming Luo, Liting Chen, Haotian Wu, Hengquan Zhao et autres

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Isopsoralen-induced hepatotoxicity: The regulatory role of endoplasmic reticulum stress-triggered mitochondrial dysfunction and apoptosis

Mingxin Yuan, Yiping Han, Pengshuo Lou, Chen Wang et autres

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A Case Report of a Novel Myelin Protein Zero ( MPZ ) Pathogenic Variant in Charcot–Marie–Tooth Disease Combined With Type 2 Diabetes

Lu Xia, Liyan Cai, Xin Chen, Kun Zhou et autres

Charcot–Marie–Tooth (CMT) disease is the collective term for the most common inherited peripheral neuropathies, affecting both motor and sensory nerves. A typical CMT patient presents with slowly progressive distal muscle weakness and atrophy that primarily involves the small foot muscles, peroneal muscles, …

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Detecting the coumarin profile in citrus fruit by a large-scale assessment of cultivated and wild accessions

Kwok Lung Fan, Ao Ding, Ou Chen, Kun Zhou et autres

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Spatially selective clearance of inflammation-mediated reactive oxygen species in injured kidney cells

Maowei Xie, Xin Yuan Fu, Yufei Lan, Yuping Zhang et autres

TFNAs@PLT offers a safe and effective therapeutic strategy for kidney injury and other inflammation-mediated diseases.

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Influence of Anesthetic Technique on the Postoperative Biological Stress Response in Thyroid Cancer Patients Receiving Psychological Intervention During Ultrasound-Guided Thyroidectomy

Yunyao Deng, Peng Mei, Kun Zhou

Objective: To examine the influence of various anesthetic techniques on the postoperative biological stress response in thyroid cancer (TC) patients receiving psychological nursing intervention during ultrasound-guided radical thyroidectomy. Methods: TC patients undergoing ultrasound-guided radical thyroidectomy at The Third Affiliated Hospital of Southern …

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M1-like macrophages regulate T cell infiltration in colorectal cancer through P2X4 receptor

Kun Zhou, Xintian Zhang, Liang Yu, Han Yao et autres

but also augmented T cell responses in a syngeneic CRC mouse model. Clinically, reduced P2X4 expression in CRC tissues correlated with poorer prognosis. In conclusion, these findings identify the P2X4R as a key regulator of M1-like TAM polarization, representing a promising target …

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Chromosome-scale genome assemblies and population re-sequence of the mango tilapia provide insights into the adaptive evolution

Lingyu Kong, Liming Luo, Kun Zhou, Yan Zhou et autres

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Navigating the genetic basis of cadmium accumulation: a comprehensive analysis of low-cadmium accumulation rice

Deyi Shao, Lixin Yin, Jian Hua Zhao, Zhengliang Luo et autres

The presence of cadmium (Cd) in rice poses a significant health risk to consumers, highlighting the urgency of breeding rice varieties with low Cd accumulation. To identify genetic resources and potential genes for developing such rice varieties, a comprehensive genome-wide association study …

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Farnesyltransferase Inhibitor (R115777) Targets CENPF to Inhibit Breast Cancer Bone Metastasis by Regulating the PI3k/AKT/mTOR/PTHrP Pathway

Jialong Liu, Jingbo Sun, Hong Fang, Junjie Luo et autres

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Chromosome-Scale Genome Assemblies and Population Re-Sequence of the Mango Tilapia Provide Insights into the Adaptive Evolution

Ying Lu, Liming Luo, Kun Zhou, Yan Hong Zhou et autres

4-Phenylbutyric acid suppresses psoralen-induced hepatotoxicity by inhibiting ERS and reestablishing mitochondrial fusion-fission balance in mice

Li Li, Bing Yu Liu, Haorui Zhang, Chen Wang et autres

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