Accès ouvert
2026
preprint
OpenAlex
Christian Cambillau, Jun Hao Liew, Bernice Siu Yan Tan, Laurent Kremer et autres
Exploring bacteriophage structural diversity is essential for understanding phage biology and for advancing phage-based therapies. Here, we determine the cryo-electron microscopy structure of Jabs, providing, to our knowledge, the first high-resolution view of a phage infecting the multidrug-resistant human pathogen Mycobacterium abscessus. …
fr, ie, sg
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Alexis Dogliani, Laura Fradale, Valeille Céline, Christian Cambillau et autres
ABSTRACT Handling membrane proteins (MPs) in their native environment is crucial for ensuring proper folding and stability. Extracellular vesicles (EVs) offer a superior alternative to detergents and artificial lipid environments. Expressing recombinant MPs on the surface of EVs allows for their display …
fr
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Alexis Dogliani, Laura Fradale, Céline Valeille, Christian Cambillau et autres
Handling membrane proteins (MPs) in their native environment is crucial for ensuring proper folding and stability. Extracellular vesicles (EVs) offer a superior alternative to detergents and artificial lipid environments. Expressing recombinant MPs on the surface of EVs allows for their display in …
fr
(code pays fourni par la source)
Accès ouvert
2026
editorial
OpenAlex
Quentin Pagneux, Alain Roussel, Hiba Saada, Christian Cambillau et autres
Editorial Expression of Concern: Communications Medicine https://doi.org/10.1038/s43856-022-00113-8 ; published online 23 May 2022
fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Kelsey D. White, Giovanni Eraclio, Gabriele Andrea Lugli, Marco Ventura et autres
Mesophilic starter cultures rely on the activity of lactic acid bacteria such as Lactococcus lactis and Lactococcus cremoris to acidify milk in dairy fermentations. Bacteriophage infection of starter bacteria remains one of the most significant threats to a successful fermentation, as they …
ie, it, de, fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Adeline Goulet, Jennifer Mahony, Douwe van Sinderen, Christian Cambillau
Bacteriophages, or phages, are sophisticated nanomachines that efficiently infect bacteria. Their infection of lactic acid bacteria (LAB) used in fermentation can lead to significant industrial losses. Among phages that infect monoderm bacteria, those with siphovirion morphology characterized by a long, non-contractile tail …
fr, ie
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Yasma Barchi, Florencia Oviedo-Hernandez, Amel Chaïb, Cécile Philippe et autres
ABSTRACT Oenococcus oeni is the predominant lactic acid bacteria species in wine, where it performs the malolactic fermentation, which helps to secure and preserve wine quality. Here, we describe the morphological, biological, and genomic characterization of siphophage Krappator X 27 , a …
fr, ie
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Brian McDonnell, Philip Kelleher, Alexey I. Fomenkov, Guillermo Ortíz Charneco et autres
The genomes of 43 distinct lactococcal strains were reconstructed by a combination of long- and short-read sequencing, resolving the plasmid complement and methylome of these strains. The genomes comprised 43 chromosomes of approximately 2.5 Mb each and 269 plasmids ranging from 2 …
ie, us, fr, ch
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Xiangan Liu, John D. Perpich, Liqiang Song, Christian Cambillau et autres
ABSTRACT The type IX secretion system (T9SS) is a protein secretion machinery unique to the Bacteroidetes-Chlorobi-Fibrobacteres superphylum, which plays crucial roles in bacterial pathogenesis and gliding motility. It is composed of >15 proteins, including the proton-motive force-dependent PorLM motor, the PorKN ring …
us, ie, fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Cas Mosterd, Andriana Grafakou, Guillermo Ortíz Charneco, Paul P. de Waal et autres
In recent years, the number of newly discovered systems that bacteria use to combat bacteriophages is increasing at an impressive rate. To obtain mechanistic insights into several antiphage systems identified in previous studies, we isolated 66 phage escape mutants which had become …
ie, ch, ca, fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Kelsey D. White, Giovanni Eraclio, Brian McDonnell, Gabriele Andrea Lugli et autres
Dairy fermentations using mesophilic starter cultures rely on the activity of specific lactic acid bacteria (LAB) such as Lactococcus lactis and Lactococcus cremoris for the acidification of milk. This biotechnological process can be affected by bacteriophage infection of LAB starter strains, which …
ie, it, fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Emmanuel Kuffour Osei, Reuben O’Hea, Christian Cambillau, Ankita Athalye et autres
Bacteriophage research has experienced a renaissance in recent years, owing to their therapeutic potential and versatility in biotechnology, particularly in combating antibiotic resistant-bacteria along the farm-to-fork continuum. However, certain pathogens remain underexplored as targets for phage therapy, including the zoonotic pathogen Streptococcus …
ie, fr, de, ae, gb
(code pays fourni par la source)