Junichi Matsumoto

Contribution of amino acid substitutions in CYP51A and CYP51B to pefurazoate resistance in Fusarium fujikuroi

Min Yu, Aki Tsukamoto, Yuri Sakahara, Shota Sado et autres

jp (code pays fourni par la source)

Characteristics of real-world driving behavior in people with schizophrenia: a naturalistic study utilizing drive recorders

Hiroki Okada, Saki Komagata, Yuichi Kamata, Junichi Matsumoto et autres

Research on driving among people with schizophrenia (PWS) is limited to laboratory-based studies. The present study aimed to compare PWS with healthy controls (HC) in real-world driving behaviors using 500 km of driving data collected through dashcams. Neuropsychological tests were conducted to …

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α-Synuclein Degradation in Brain Pericytes Is Mediated via Akt, ERK, and p38 MAPK Signaling Pathways

Miki Yokoya, Fuyuko Takata, Takuro Iwao, Junichi Matsumoto et autres

Parkinson's disease (PD) is characterized by widespread distribution of Lewy bodies, which are composed of phosphorylated and aggregated forms of α-Synuclein (α-Syn), in the brain. Although the accumulation and propagation of α-Syn contribute to the development of PD, the involvement of the …

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Comparative analysis of lipolytic enzymes involved in the surface fermentation of dried katsuobushi by xerophilic molds

Shinji Takenaka, Tomoya Umeki, Yukihiro Kimura, Shin‐ichi Tanaka et autres

BACKGROUND: Fermented katsuobushi, a traditional Japanese seasoning, is produced from skipjack tuna through smoking, drying and fermentation by xerophilic Aspergillus molds, primarily Aspergillus chevalieri and Aspergillus pseudoglaucus. In this study, we characterized lipolytic enzymes (cLip_1 to cLip_5 and pLip_1 to pLip_3) to …

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Comparative Analysis of Lipolytic Enzymes Involved in the Surface-Fermentation of Dried Katsuobushi by Xerophilic Molds

Shinji Takenaka, Tomoya Umeki, Yukihro Kimura, Shin‐ichi Tanaka et autres

Bortezomib Increased Vascular Permeability by Decreasing Cell–Cell Junction Molecules in Human Pulmonary Microvascular Endothelial Cells

Taichi Matsumoto, Junichi Matsumoto, Yuka Matsushita, Moeno Arimura et autres

Bortezomib (BTZ), a chemotherapeutic drug used to treat multiple myeloma, induces life-threatening side effects, including severe pulmonary toxicity. However, the mechanisms underlying these effects remain unclear. The objectives of this study were to (1) investigate whether BTZ influences vascular permeability and (2) …

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A two‐way coupling 2D‐3D hybrid finite element numerical model using overlapping method for tsunami simulation

Guoming Ling, Junichi Matsumoto, Kazuo Kashiyama

Abstract This paper describes a 2D‐3D hybrid model for tsunami simulations that uses an overlapping method based on an arbitrary grid. A 2D model is used to simulate wave propagation from the source area to the offshore area, and a 3D model …

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Association of T cell infiltration and morphological change of thymus gland with the aggravation of pulmonary emphysema in testosterone deficiency

Kentaro Aono, Junichi Matsumoto, Taichi Matsumoto, Mitsuhisa Koga et autres

Chronic obstructive pulmonary disease is an inflammatory lung disease characterized by chronic bronchitis and emphysema. Our previous study revealed that testosterone depletion induced T cell infiltration in the lungs and aggravated pulmonary emphysema in orchiectomized (ORX) mice exposed to porcine pancreatic elastase …

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Exploring the potential of katsuobushi grounds as a source of bioactive peptides through fermentation with Aspergillus sydowii

Shinji Takenaka, Masaki Kato, Yasuhiro Oribe, Yukihiro Kimura et autres

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Improvement in salt-tolerance of Aspergillus oryzae γ-glutamyl transpeptidase via protein chimerization with Aspergillus sydowii homolog

Hironori Senba, Arisa Nishikawa, Yukihiro Kimura, Shin‐ichi Tanaka et autres

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Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice

Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Hisataka Aridome et autres

Nutrients are actively taken up by the brain via various transporters at the blood-brain barrier (BBB). A lack of specific nutrients in the aged brain, including decreased levels of docosahexaenoic acid (DHA), is associated with memory and cognitive dysfunction. To compensate for …

jp (code pays fourni par la source)

A two-way coupling 2D-3D hybrid finite element numerical model using overlapping method for tsunami simulation

Guoming Ling, Junichi Matsumoto, Kazuo Kashiyama

This paper describes a 2D-3D hybrid model for tsunami simulations that uses an overlapping method based on an arbitrary grid. A 2D model is used to simulate wave propagation from the source area to the offshore area, and a 3D model is …

jp (code pays fourni par la source)