Siyu Luo

The m6A methyltransferase METTL14 promotes oncogenic Kras induced juvenile myelomonocytic leukemia through dysregulating autophagy

Peihua Zhang, Keping Feng, Xiao Yu, Siyu Luo et autres

Abstract The N6-methyladenosine (m6A) modification plays an important role in the pathogenesis of various myeloid malignancies. However, its specific role in RAS mutation-induced myeloid malignancy is incompletely understood. In this study, we found that m6A methyltransferase methyltransferase-like 14 (METTL14) was highly expressed …

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Triceps skinfold-albumin index predicts overall survival of malignant tumors in at least two organs: a multicentre cohort study

Feifei Chong, Zhenyu Huo, Ning Tong, Xin Lin et autres

Abstract Background The present study evaluated the prognostic value of a new published joint index, the fat mass triceps skinfold-albumin index (TA) in patients with malignant tumors in at least two organs (MTT). Methods Patients for this study were recruited prospectively as …

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Potential framework of the Global Leadership Initiative in Sarcopenia (GLIS) criteria based on muscle mass and/or strength for predicting survival in cancer patients: A nationwide multicenter cohort study

Zhenyu Huo, Feifei Chong, Siyu Luo, Na Li et autres

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Arachidonic acid promotes myeloid differentiation of splenic CD45- Ter119+ cells in myeloproliferative neoplasm

Linlin Zhang, Yi Yang, Xiao Yu, Guodong Li et autres

Although splenic CD45 -Ter119 + cells promote cancer progression by secreting artemin, it remains unclear whether these cells play an important role in myeloproliferative neoplasm (MPN).Here, using a Kras G12D/+ -induced mouse model of MPN, we demonstrated that the number and cycling …

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Diagnostic Criteria for Cancer‐Associated Cachexia: Insights from a Multicentre Cohort Study

Zhenyu Huo, Feifei Chong, Na Li, Siyu Luo et autres

BACKGROUND: To explore the association between cachexia, as defined by different diagnostic criteria, and the risk of mortality in individuals with cancer. We also examined which diagnostic criteria are more feasible and appropriate for cancer-associated cachexia in clinical practice. METHODS: A multicentre …

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Ability of the modified NUTRIC score to predict all-cause mortality among ICU patients with acute pancreatitis: A retrospective analysis using the MIMIC-IV database

Ning Tong, Haibin Lu, Na Li, Zhenyu Huo et autres

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Reply to the comment on “Value of the modified Patient‐ Generated Subjective Global Assessment in indicating the need for nutrition intervention and predicting overall survival in patients with malignant tumors in at least two organs.”

Feifei Chong, Zhenyu Huo, Siyu Luo, Ning Tong et autres

In response to the questions raised, we have attempted to further analyze the data to explore the differences in survival between different cancer types and various methods of nutritional intervention. Due to the inclusion of multiple histological tumor types in this study …

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Thin and Robust Template-Reinforced Anion Exchange Membranes for Fuel Cells, Oil-Water Separation, and Humidity-Responsive Applications

Wenting Lan, Yafei Xiao, Minghua Zhang, Siyu Luo et autres

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Utilizing machine learning approaches to investigate the relationship between cystatin C and serious complications in esophageal cancer patients after esophagectomy

Zhenyu Huo, Feifei Chong, Siyu Luo, Ning Tong et autres

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Grip-Strength-Lean-Mass Index (GSLMI) as a valuable tool for sarcopenia diagnosis and survival prognosis in cancer patients: a nationwide multicenter cohort study

Zhenyu Huo, Feifei Chong, Siyu Luo, Na Li et autres

OBJECTIVES: To identify whether the Grip-Strength-Lean-Mass Index (GSLMI) can precisely diagnose sarcopenia and predict prognosis for cancer patients in clinical settings. DESIGN: A nationwide multicenter cohort study. SETTING AND PARTICIPANTS: 8,831 inpatients aged 18 years and older, histologically diagnosed with cancer and …

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Global Leadership Initiative in Sarcopenia (GLIS)–defined sarcopenia increases the mortality of esophageal cancer patients after esophagectomy: A Chinese real-world cohort study

Zhenyu Huo, Siyu Luo, Feifei Chong, Ning Tong et autres

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Development and validation of a diagnostic nomogram for frailty in cancer patients

Siyu Luo, Feifei Chong, Zhenyu Huo, Jie Liu et autres

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