Na Li

Targeting ER Stress of GLP-1 Receptor Agonist in Diabetic Retinopathy

Hanwen Huang, Yanuo Wang, Shuang Gao, Na Li et autres

GLP-1 receptor agonists (GLP-1RAs) were initially used for glycemic control in type 2 diabetes, but studies in recent years have found that they may have potential therapeutic effects in diabetic retinopathy (DR). DR is a leading cause of vision loss in diabetes, …

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Endotracheal intubation-related oral mucosal membrane pressure injuries: a narrative review of biomechanical insights, biomaterial optimization, and intelligent monitoring

Limei Cai, Yijing Li, Yonggang Liu, Ma Guo et autres

Objectives: This article is a narrative review that synthesizes current evidence on orotracheal intubation-related oral mucosal membrane pressure injuries in intensive care unit (ICU) patients, focusing on mechanisms, risk factors, and prevention strategies. The review is intended to inform clinicians and researchers …

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Facile fabrication of twisted MoS 2 bilayers by direct bonding

Yutong Chen, Jie-Ying Liu, Lanying Zhou, Hua Yu et autres

Abstract When stacking two-dimensional (2D) materials with a lattice mismatch and/or a small twist, moiré superlattice emerges with fascinating electronic and optical properties. The fabrication of such stacked 2D materials usually requires multiple transfer and stack processes, assisted by a certain transfer …

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Concurrent anti-glomerular basement membrane disease and membranous nephropathy: a case report

Linlin Li, Panxin Niu, Na Li, Xiaoling Zhang et autres

Anti-glomerular basement membrane (GBM) disease is a rapidly progressive glomerulonephritis which, in rare instances, occurs concurrently with membranous nephropathy (MN). We report a case of this patient presented with proteinuria and hematuria, the predominant pathology was crescentic and necrotizing glomerulonephritis with linear …

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Nutritional regulation by vitamin A: Comprehensive impacts on growth, molting, immunity, lipid metabolism, and ovarian maturation in red swamp crayfish (Procambarus clarkii)

Jiacheng Yu, Siying Hu, Fuxian Zhang, Yihan Wu et autres

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Enhanced In2O3 gas sensitivity to ethanol via synergistic effect of Gd doping and MOF-derivation

Juntang Dong, Junwei Li, Tingting Shao, Fuchun Zhang et autres

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HMGB1 couples LEF1 to regulate B cell immunity

Qiuyue Chen, Ziyin Zhang, Nanshu Xiang, Li Luo et autres

Secreted high mobility group box protein 1 (HMGB1) regulates the adaptive immune response and acts as a biosensor for cells undergoing necrosis, stress, and inflammatory stimulation. However, its role in B cells remains enigmatic. Here, we demonstrate that HMGB1 is critical for …

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Epigenetic landscape of IL-10 in Graves’ disease: site-specific DNA methylation alterations and their associations with immune dysregulation

Wenyu Xu, Yalin Wang, Guangxin Li, Jing Zhang et autres

OBJECTIVE: Epigenetic modifications, particularly deoxyribonucleic acid (DNA) methylation, regulate the expression of immune-mediated factors. This study aimed to investigate the methylation landscape of the interleukin-10 (IL10) gene in Graves' disease (GD). METHODS: This study quantitatively profiled DNA methylation levels within the IL-10 …

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953P Efficacy of the TLR7 agonist CAN1012 alone or combined with the anti-PD-1 antibody toripalimab

Jimin Zhao, Herui Yao, Na Li, Yun Chen et autres

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Effect of Ce doping on the microstructure and ethylene glycol sensing performance of ZnO

Juntang Dong, Na Li, Tingting Shao, Tianli Duan et autres

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Immune Modulatory Effects of PD ‐1/ PD ‐ L1 in Myasthenia Gravis: Insights From Peripheral Blood Mononuclear Cell Analysis

Jianing Li, Xinyue Liu, Feiteng Qi, Yan Ren et autres

ABSTRACT Myasthenia gravis (MG) is an autoimmune disease characterized by the production of antibodies targeting acetylcholine receptor (AChR)‐associated proteins. The disorder involves various immune cells, including T cells, B cells, and dendritic cells (DCs). Programmed cell death protein 1 (PD‐1) is one …

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PAI-1 regulates extracellular matrix remodeling and alters fibroblast profibrotic ability in skeletal muscle repair

Na Li, Xingyu Lu, Jieyun Zhang, Li-hong Dang et autres

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