Shihao Nie

Acutely denervated muscle EVs reshape neuronal mitochondrial metabolism via retrograde signaling to rescue peripheral nerve injury

Qi Liu, Borui Xue, Yongfeng Zhang, Mingze Qin et autres

Peripheral nerve injury causes muscle atrophy due to slow axonal regeneration, highlighting an unmet therapeutic need. Although neuromuscular interactions are classically viewed as unidirectionally nerve dominated, we show that acutely denervated muscle (adMu) regulates nerve regeneration via a retrograde signaling pathway. adMu …

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Bone-targeted mitochondrial delivery via magnetic-temperature responsive artificial cells for repairing age-related fractures

Shihao Nie, Yue Yu, Rong Lin Yan, Liu Taoran et autres

Background: Age-related bone diseases, such as osteoporosis and degenerative joint disorders, pose a significant global health challenge, leading to over 9 million fractures annually, which not only diminishes quality of life but also imposes a substantial socioeconomic burden on healthcare systems. A …

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A Time-Scheduled Oxygen Modulation System Facilitates Bone Regeneration by Powering Periosteal Stem Cells

Yujie Yang, Xue Jun Gao, Yongfeng Zhang, Shengyou Li et autres

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A Novel Deer Antler‐Inspired Bone Graft Triggers Rapid Bone Regeneration

Shengyou Li, Yujie Yang, Beibei Yu, Xueli Gao et autres

Adult mammals are unable to regenerate bulky bone tissues, making large bone defects clinically challenging. Deer antler represents an exception to this rule, exhibiting the fastest bony growth in mammals, offering a unique opportunity to explore novel strategies for rapid bone regeneration. …

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Reconfiguring the Escherichia coli Electron Transport Chain to Enhance trans-2-Decenoic Acid Production

Ben Liu, Haoyang Wang, Chunli Su, Y.F. Zhang et autres

trans -2-Decenoic acid is a pivotal α,β-medium-chain unsaturated fatty acid that serves as an essential intermediary in the synthesis of 10-hydroxy-2-decenoic acid and various pharmaceutical compounds. Biosynthesis yield of trans -2-decenoic acid by decanoic acid has significantly improved in recent years; however, …

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Fabrication of a superhydrophobic cotton@LDH composite for effective oil adsorption

Shihao Nie, Atian Xie, Jiangping Rui, Jiawei Meng et autres

The development of superhydrophobic materials with inexpensive cost, and simple preparation processes is crucial for alleviating oil pollution.

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Low-pressure driving Co3O4/PAN nanofiber membrane with peroxymonosulfate activation self-cleaning for efficient wastewater purification

Hengchao Liang, Atian Xie, Shihao Nie, Jiangping Rui et autres

Nanofiber membrane separation technologies are promising for separation of emulsions, but it is still limited by membrane fouling . Herein, a new low-pressure driving Co 3 O 4 /polyacrylonitrile (PAN) nanofiber membrane (CPNFM) with peroxymonosulfate (PMS) activation self-cleaning ability was developed by …

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Optimization of Fermentation Conditions for Biocatalytic Conversion of Decanoic Acid to Trans-2-Decenoic Acid

Shihao Nie, Keyi Liu, Ben Liu, Piwu Li et autres

Trans-2-decenoic acid has a wide range of applications, including those in medicine, food, and health care. Therefore, the industrial production of trans-2-decenoic acid is particularly important. However, few studies have focused on medium-chain unsaturated fatty acids. Therefore, we aimed to optimize the …

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Optimization of Fermentation Conditions for Biocatalytic Synthesis of Trans-2-Decenoic Acid from Decanoic Acid

Shihao Nie, Keyi Liu, Ben Liu, Piwu Li et autres

To study the fermentation process of biocatalyzing decanoic acid to synthesize trans-2-decenoic acid, this study was based on the engineering E.coli constructed in the laboratory in the early stage and studied the effect of seed liquid culture time, culture temperature, inoculum amount, …

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Fabrication, Characterization, and Application of Anti-Fouling Co3o4/Pes Composite Nanofiltration Membrane for Dye Removal

Jian Xu, Jiuyun Cui, Shihao Nie, Jiangping Rui et autres

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