Shengyou Li

Targeting microglial MyD88 reprograms injury-activated microglia and promotes spinal cord repair via TGF-β signaling and biomimetic nanodelivery

Jintao Liu, Beibei Yu, Wanjun Cao, Jilu Liu et autres

Background: Following spinal cord injury (SCI), activated microglia sustain neuroinflammation and drive secondary tissue damage, and this limits functional recovery. Myeloid differentiation primary response 88 (MyD88) is a central adaptor of innate immune signaling, but whether and how microglial MyD88 regulates state …

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Phenotyping elucidates the association between traits and bioactive components in Notopterygium incisum

Ping Chen, Yili Zhang, Xiaoyan Zheng, Jingyao Tang et autres

BACKGROUND: Natural products enriched in medicinal plants have broad prospects in addressing global public health challenges and meeting diverse human health needs. The traditional Chinese herbal medicine Notopterygii Rhizoma et Radix (NRR) is the dried rhizome and root of Notopterygium incisum Ting …

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Correction to “A Novel Superparamagnetic Multifunctional Nerve Scaffold: A Remote Actuation Strategy to Boost In Situ Extracellular Vesicles Production for Enhanced Peripheral Nerve Repair”

Bing Xia, Xue Gao, Jiaqi Qian, Shengyou Li et autres

In preparing the figures for publication, the image for the co-incubation of PKH26-labeled SCs-EVs Mag+RMF and 𝛽-tubulin III-labeled DRG neurons in Figure 3E was mistakenly placed with the image of FITC-phalloidin-labeled DRG neurons. (2 of 2)15214095, 0, Downloaded from https://advanced.onlinelibrary.

Extracellular vesicles from antler blastema progenitor cells reverse bone loss and mitigate aging-related phenotypes in mice and macaques

Yiming Hao, Beibei Yu, Tao Qin, Yitao Wei et autres

Antler blastema progenitor cells (ABPCs) are a distinct population of skeletal mesenchymal stem cells found in regenerating deer antlers, with strong stemness and renewal capacity in vitro. Stem cell-derived extracellular vesicles (EVs) are emerging as potential therapeutic candidates that can mediate donor …

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Oxygen carrier in core-shell fibers synthesized by coaxial electrospinning enhances Schwann cell survival and nerve regeneration: Erratum

Teng Ma, Yafeng Yang, Xin Quan, Lei Lü et autres

[This corrects the article DOI: 10.7150/thno.45035.].

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A novel L-shaped ortho-quinone analog targeting adenosine A2b receptor to inhibit epithelial-mesenchymal transition in colorectal cancer cells

Rui Wang, Jia Yu, Xinwei Wan, Shengyou Li et autres

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Corrigendum to “Hydralazine represses Fpn ubiquitination to rescue injured neurons via competitive binding to UBA52” [J. Pharm. Anal. 14 (2024) 86–99]

Shengyou Li, Xue Jun Gao, Yi Zheng, Yujie Yang et autres

[This corrects the article DOI: 10.1016/j.jpha.2023.08.006.].

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Corrigendum: Epothilone B facilitates peripheral nerve regeneration by promoting autophagy and migration in Schwann cells

Jianhua Zhou, Shengyou Li, Jianbo Gao, Yawei Hu et autres

• please read through all the templates before choosing • pick the most relevant text template(s) from the following page and delete all others.• edit the text as necessary, ensuring that the original incorrect text is included for the record, please see …

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A Time-Scheduled Oxygen Modulation System Facilitates Bone Regeneration by Powering Periosteal Stem Cells

Yujie Yang, Xue Jun Gao, Yongfeng Zhang, Shengyou Li et autres

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Metabolic Reprogramming of Neural Stem Cells by Chiral Nanofiber for Spinal Cord Injury

Haining Wu, Chao Xing, Beibei Yu, Lingli Guo et autres

Exogenous neural stem cells (NSCs) have great potential to reconstitute damage spinal neural circuitry. However, regulating the metabolic reprogramming of NSCs for reliable nerve regeneration has been challenging. This report discusses the biomimetic dextral hydrogel (DH) with right-handed nanofibers that specifically reprograms …

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Engineered Extracellular Vesicles from Antler Blastema Progenitor Cells: A Therapeutic Choice for Spinal Cord Injury

Shijie Yang, Borui Xue, Yongfeng Zhang, Haining Wu et autres

High Resolution Image Download MS PowerPoint Slide Deer antler blastema progenitor cells (ABPCs) are promising for regenerative medicine due to their role in annual antler regeneration, the only case of complete organ regeneration in mammals. ABPC-derived signals show great potential for promoting …

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Neonatal-Inspired Reprogramming of Microglial Pan-Programmed Cell Death Enhances Regeneration in Adult Spinal Cord Injury

Beibei Yu, Yongfeng Zhang, Yujie Yang, Shijie Yang et autres

In adult mammals, programmed cell death (PCD) facilitates tissue remodeling and regeneration in spinal cord injury (SCI), but excessive activation impedes SCI repair. However, no comprehensive pan-PCD atlas exists that encompasses diverse cell death patterns to fully elucidate PCD in adult SCI …

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