Yujie Yang

Piroxicam accelerates diabetic foot ulcer healing via ERα-dependent mitochondrial protection and oxidative stress relief

Qingqing Liao, Li Chen, Jia-Qi Zheng, Yujie Yang et autres

Introduction: The pathology of diabetic foot ulcer (DFU) is characterized by keratinocyte dysfunction, non-resolving inflammation, and oxidative stress. We aim to investigate the effects and mechanisms of piroxicam on DFU healing through regulating mitochondrial function and suppressing inflammation. Methods: DFU was established …

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Emergence and genomic characterization of mcr-8.2-positive Klebsiella pneumoniae from layer chickens in Xinjiang, China

Rui Tian, Mengqi Yang, Yujie Yang, Shuqin Xu et autres

(10.5%) showed lower prevalence. The overall detection rate of mcr genes (mcr-1 to mcr-9) was low (0.5%). ESBL-producing isolates were identified in 9.8% (n = 40) of the total strains, indicating the presence of extended-spectrum β-lactamase-mediated resistance mechanisms. Importantly, two mcr-8.2 positive …

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Exploring therapeutic mechanism of Fuzhenghefuzhiyang Formula in psoriasis: inflammation and metabolism regulation

Bin Tang, Chen Zhang, Yujie Yang, Haixin Zhong et autres

Background: Psoriasis is a long-term, immune-mediated inflammatory disorder of the skin, affecting about 2-3% of the global population with rising prevalence rates. Clinical practice has demonstrated that Fuzhenghefuzhiyang formula (FZHFZY), a topical medication applied Chinese herbal formula developed by Prof. Lu Chuanjian, …

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Infection-adaptive regenerative wound healing through rationally engineered copper-polyphenol artificial enzymes enabling quadruple-modal ROS cascade modulation in pathological microenvironments

Lina Sun, Liman Liu, Weiwei Shi, Yujie Yang et autres

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CircCDYL promotes glycolysis to drive the progression of nasopharyngeal carcinoma

Yujie Yang, Yian Wang, Hongke Qu, Dan Wang et autres

CircCDYL enhances LDHA mRNA stability in NPC by binding to its 3′-UTR, resulting in increased LDHA protein levels and enhanced glycolysis in NPC cells. This leads to lactate accumulation, which, under the catalysis of AARS1, induces lactylation of CFL1 at the K22 …

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Human adenovirus penton dodecahedron nanoparticles induce an enhanced neutralizing antibody response in mouse model

Liling Zhou, Yujie Yang, Chuncong Mo, Yuhui Zhu et autres

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A simplified in-situ extraction method for pyrethroid pesticides from complex food matrix through pore-switching response based on rationally designed Zr-MOFs with anti-interference performance

Lei Huang, Qianwen Yang, Yujie Yang, Tai Ye et autres

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Aerobic exercise prevents renal osteodystrophy via irisin-activated osteoblasts

Meng Wu, Huilan Li, Xiaoting Sun, Rongrong Zhong et autres

Renal osteodystrophy is commonly seen in patients with chronic kidney disease (CKD) due to disrupted mineral homeostasis. Given the impaired renal function in these patients, common antiresorptive agents, including bisphosphonates, must be used with caution or even contraindicated. Therefore, an alternative therapy …

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A Time-Scheduled Oxygen Modulation System Facilitates Bone Regeneration by Powering Periosteal Stem Cells

Yujie Yang, Xue Jun Gao, Yongfeng Zhang, Shengyou Li et autres

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Corrigendum: The causal relationship between serum metabolites and the risk of psoriasis: a Mendelian randomization and meta-analysis study

Yujie Yang, Xuwei Zheng, Haiying Lv, Bin Tang et autres

In the published article, there was an error in Figure 4 as published. The duplicate Figure 4B was mistakenly uploaded to the position of Figure 4C. The corrected Figure 4 and its caption (A) displays the heterogeneity and pleiotropy analysis results of …

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Strategic configuration of geothermal backfill materials using industrial solid waste for low-carbon building energy systems

Xuemin Xia, Yue Sun, Simin Jiang, Wan Sun et autres

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The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review

Bin Tang, Yang Bi, Xuwei Zheng, Yujie Yang et autres

Psoriasis is a chronic inflammatory polygenic disease with significant impacts on skin and joints, leading to substantial treatment challenges and healthcare costs. The quest for novel therapeutic avenues has recently highlighted extracellular vesicles (EVs) due to their potential as biomarkers and therapeutic …

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