Dragoş Niculescu

CMEMS’ Downstream Operational Services for the monitoring-modeling-management of the marine and coastal areas of the western Black Sea Basin

Răzvan Mateescu, Adelio Silva, Luc Vandenbulcke, Elena Vlăsceanu et autres

The western Black Sea basin is a region of scientific interest in terms of its past and present level of ecological degradation by anthropogenic influences among the European Seas. Its coastal areas are the subject of continuous remote monitoring and operational observing …

Enhanced production of mesencephalic dopaminergic neurons from lineage-restricted human undifferentiated stem cells

Muyesier Maimaitili, Muwan Chen, Fabia Febbraro, Ekin Ucuncu et autres

Current differentiation protocols for generating mesencephalic dopaminergic (mesDA) neurons from human pluripotent stem cells result in grafts containing only a small proportion of mesDA neurons when transplanted in vivo. In this study, we develop lineage-restricted undifferentiated stem cells (LR-USCs) from pluripotent stem …

dk, it (code pays fourni par la source)

Immunohistochemical expression of p53, Ki67, α-SMA, CD44 and CD31 in different histological subtypes of basal cell carcinoma

Anca Cojocaru, Carrol Bîrjovanu, Ana-Maria Ciurea, Dragoş Niculescu et autres

Basal cell carcinoma (BCC) is a common, locally invasive tumor that arises within sun-damaged skin and rarely develops on the palms and soles or mucous membranes. Men generally have higher rates of BCC than women. Incidence also increases with age and the …

ro, us (code pays fourni par la source)

Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch

Takuma Kumamoto, Franck Maurinot, Raphaëlle Barry‐Martinet, Célia Vaslin et autres

Stable genomic integration of exogenous transgenes is essential in neurodevelopmental and stem cell studies. Despite tools driving increasingly efficient genomic insertion with DNA vectors, transgenesis remains fundamentally hindered by the impossibility of distinguishing integrated from episomal transgenes. Here, we introduce an integration-coupled …

fr (code pays fourni par la source)

Cortical astrocytes develop in a plastic manner at both clonal and cellular levels

Solène Clavreul, Lamiae Abdeladim, Edwin Hernández-Garzón, Dragoş Niculescu et autres

Astrocytes play essential roles in the neural tissue where they form a continuous network, while displaying important local heterogeneity. Here, we performed multiclonal lineage tracing using combinatorial genetic markers together with a new large volume color imaging approach to study astrocyte development …

fr (code pays fourni par la source)

IDEEA DE UNITATE A UNIVERSULUI ÎN DIALECTICĂ, CU INTERPRETĂRI TRANSCENTIVE

Dragoş Niculescu

La începutul studiului, câteva aspecte, ca linii directoare: "nu doar materialitate şi idealitate; şi nu dualitate, ci materialitatea ca dat şi creat, coordonat, potenţat şi valorificat al spiritualului"; "explicarea existenţei şi rostului materialităţii prin dorinţa şi scopul idealităţii, al Spiritului Absolut"; "explicarea …

A BDNF-Mediated Push-Pull Plasticity Mechanism for Synaptic Clustering

Dragoş Niculescu, Kristin Michaelsen‐Preusse, Ülkü Güner, René van Dorland et autres

During development, activity-dependent synaptic plasticity refines neuronal networks with high precision. For example, spontaneous activity helps sorting synaptic inputs with similar activity patterns into clusters to enhance neuronal computations in the mature brain. Here, we show that TrkB activation and postsynaptic brain-derived …

nl, fr, us (code pays fourni par la source)

Spontaneous Activity Drives Local Synaptic Plasticity In Vivo

Johan Winnubst, Juliette E. Cheyne, Dragoş Niculescu, Christian Löhmann

nl (code pays fourni par la source)

Aspiration pneumonia in an infant with neurological sequelae - case report.

Dalia Dop, Cristian Gheonea, Georgeta Ligia Stănescu, Aritina Moroşanu et autres

Aspiration pneumonia is a frequent cause of morbidity and mortality in children with neurological deficits. We present the case of a 4-month-old infant from the Foster Care Center, with severe psychomotor retardation, blindness, and associated cardiac malformation, who was admitted to the …

ro, gb (code pays fourni par la source)

The Mistery of the Eminescian Science

Mircea Pteancu, Virgil Scurtu, Michel Ardan, Alex Gaina et autres

Erg Potassium Currents of Neonatal Mouse Purkinje Cells Exhibit Fast Gating Kinetics and Are Inhibited by mGluR1 Activation

Dragoş Niculescu, Wiebke Hirdes, Sönke Hornig, Olaf Pongs et autres

We investigated the subthreshold properties of an erg (ether-à-go-go-related gene) K(+) current in Purkinje cells of neonatal mice. Action potentials recorded from Purkinje cells in cerebellar slices exhibited a decreased threshold potential and increased frequency of spontaneous and repetitive activity following application …

de (code pays fourni par la source)

Aspects of the Coastal Hydro-Geomorphological Processes at the Danube River Mouths

Răzvan Mateescu, Angela S. Ivan, Ichinur Omer, Dorin Butunoiu et autres