Accès ouvert
2021
article
OpenAlex
Vincent Mouilleau, Célia Vaslin, Rémi Robert, Simona Gribaudo et autres
Rostro-caudal patterning of vertebrates depends on the temporally progressive activation of HOX genes within axial stem cells that fuel axial embryo elongation. Whether the pace of sequential activation of HOX genes, the 'HOX clock', is controlled by intrinsic chromatin-based timing mechanisms or …
fr, us
(code pays fourni par la source)
Accès ouvert
2020
preprint
OpenAlex
Vincent Mouilleau, Célia Vaslin, Simona Gribaudo, Rémi Robert et autres
SUMMARY Rostro-caudal patterning of vertebrates depends on the temporally progressive activation of HOX genes within axial stem cells that fuel axial embryo elongation. Whether HOX genes sequential activation, the “ HOX clock”, is paced by intrinsic chromatin-based timing mechanisms or by temporal …
fr, us
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Takuma Kumamoto, Franck Maurinot, Raphaëlle Barry‐Martinet, Célia Vaslin et autres
Stable genomic integration of exogenous transgenes is essential in neurodevelopmental and stem cell studies. Despite tools driving increasingly efficient genomic insertion with DNA vectors, transgenesis remains fundamentally hindered by the impossibility of distinguishing integrated from episomal transgenes. Here, we introduce an integration-coupled …
fr
(code pays fourni par la source)
Accès ouvert
2019
preprint
OpenAlex
Takuma Kumamoto, Franck Maurinot, Raphaëlle Barry‐Martinet, Célia Vaslin et autres
SUMMARY Stable genomic integration of exogenous transgenes is critical for neurodevelopmental and neural stem cell studies. Despite the emergence of tools driving genomic insertion at high rates with DNA vectors, transgenesis procedures remain fundamentally hindered by the impossibility to distinguish integrated transgenes …
fr
(code pays fourni par la source)
Accès ouvert
2019
article
OpenAlex
Nathalie Duval, Célia Vaslin, Tiago Barata, Youcef El-Mokhtar Frarma et autres
ABSTRACT Bone morphogenetic proteins (BMPs) are secreted regulators of cell fate in several developing tissues. In the embryonic spinal cord, they control the emergence of the neural crest, roof plate and distinct subsets of dorsal interneurons. Although a gradient of BMP activity …
fr
(code pays fourni par la source)
Accès ouvert
2019
preprint
OpenAlex
Nathalie Duval, Célia Vaslin, Tiago Barata, Stéphane Nedelec et autres
Abstract Bone Morphogenetic Proteins (BMP) are secreted regulators of cell fate in several developing tissues. In the embryonic spinal cord, they control the emergence of the neural crest, roof plate and distinct subsets of dorsal interneurons. Although a gradient of BMP activity …
fr
(code pays fourni par la source)