Ping Song

Reported device problems and patient outcomes in da Vinci robotic robotic gastric and upper-gastrointestinal procedures: an FDA MAUDE database analysis

Ping Song, Dawei Sun

cn (code pays fourni par la source)

Metabolic stress-activated endothelial STING rewires the sinusoidal immune niche in MASLD

Zhibin Lin, Peng Zou, Xian-Yi Ma, Jun-Bo Song et autres

Liver sinusoidal endothelial cells (LSECs) regulate nutrient flux and immune surveillance within the hepatic niche, yet how they function as metabolic stress sensors that instruct adaptive immune remodeling during metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear. Here, single-nucleus transcriptomics of human …

cn (code pays fourni par la source)

Decoding lactylation heterogeneity in glioblastoma: machine learning identifies G6PC3 as a prognostic target

Liu Y, Hao Deng, Ping Song, Qingya Qiu et autres

BACKGROUND: Glioblastoma (GBM) is the most common malignant glioma in adults. It has an extremely poor prognosis, highlighting an urgent need for new therapeutic strategies to improve patient survival. Lactylation is a novel post-translational modification (PTM) that modulates tumor progression through multiple …

cn (code pays fourni par la source)

Ketone Ester Attenuates Thoracic Aortic Aneurysm and Dissection by Suppressing Ferroptosis

Sanjiv Shrestha, Yang Wu, Jian Li, Xin Du et autres

Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening vascular disease lacking therapies that target underlying cell death pathways. Ferroptosis, an iron-dependent form of lipid peroxidation-driven cell death, has emerged as a key mechanism in vascular remodeling. We investigated whether exogenous ketosis …

us (code pays fourni par la source)

Dual Regulation of Post-Translational Modification of Proteins: Bottlenecks and Breakthroughs in NK Cell Therapy for Glioblastoma

Yushu Liu, Qingya Qiu, Hui Deng, Ping Song et autres

Glioblastoma (GBM) is the most malignant primary central nervous system tumor in adults, with strong invasiveness, high recurrence, and poor prognosis. Natural killer (NK) cells, innate immune cells that eliminate glioma stem cells without MHC matching, show promise for GBM immunotherapy, but …

cn (code pays fourni par la source)

Retraction notice to “Experimental study of blood pressure and its impact on spontaneous hypertension in rats with Xin Mai Jia” [Biomed. Pharmacother. 112 (2019) 108689]

Yun Jing, Jiajing Hu, Jierong Zhao, Jing Yang et autres

cn (code pays fourni par la source)

IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma

Xuehua Zhang, Guoyan Wang, Yujiao Gong, Leilei Zhao et autres

[This corrects the article DOI: 10.1016/j.isci.2023.106639.].

Accelerating epigenetic age in right-sided colon cancer predicts a favorable outcome

Qin Ye, Ping Song, Wangxiong Hu, G. Y. Zhang

BACKGROUND: DNA methylation age, referred to as 'epigenetic age, epiAge' is an accurate biomarker for aging, including cancer. As a well established age-associated disease, colorectal cancer (CRC) is a highly heterogeneous cancer and can be divided into left-sided colon cancer (LCC), right-sided …

cn (code pays fourni par la source)

Synergistic promotion of diabetic wound healing by glucose-responsive functional chitosan-based composite nanohydrogels

Runze Yang, Jiale Sun, Guanglan Peng, Mingcai Wu et autres

cn (code pays fourni par la source)

Application of neural stem cells in the treatment of intracerebral hemorrhage: a systematic review

Ping Song, Zohaib Shafiq, Hongxiang Jiang, Qiang Cai

Stroke ranks among the top global causes of death and disability, with hemorrhagic stroke accounting for 9%-27% of cases. In China, intracerebral hemorrhage (ICH) outpaces Western rates, driving adult mortality and disability. Aging populations and urbanization diversify stroke risk factors, yielding a …

cn (code pays fourni par la source)

Incidence, severity, and risk factors of early postoperative complications in laryngectomy patients: a retrospective analysis

Meiqin Shi, Ping Song, Kun Du, Lei Tao et autres

To determine the incidence, severity and risk factors of complications in patients undergoing laryngectomy. 433 patients with hypopharyngeal and laryngeal carcinomas who underwent laryngectomies from February 2023 to October 2023 were enrolled in this retrospective study. Clinical data of the patients were …

cn (code pays fourni par la source)

Abstract 4370545: β-Hydroxybutyrate Inhibits Thoracic Aortic Aneurysm and Dissection in Mice by Suppressing Ferroptosis

Sanjiv Shrestha, Ping Song

Background: Thoracic aortic aneurysm and dissection (TAAD) is a severe vascular disease that poses life-threatening risks. Unfortunately, managing and treating TAAD remains challenging due to the absence of approved and effective pharmacological therapies. Recent studies have indicated that supplementation with the ketone …

us (code pays fourni par la source)