Heterogeneity of Transitional Alveolar Epithelial States
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Matthew G. Jones, Dawei Sun, Kyung Hoi Min, William Colgan et autres
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Eimear N Rutherford, Dawei Sun, Kyungtae Lim, Christopher S Godbehere et autres
Alveolar type 2 (AT2) cell dysfunction is key to the development of many lung diseases including pulmonary fibrosis (PF). The underlying mechanisms often remain poorly understood due to a paucity of manipulable primary human models and lack of defined triggers. Monogenic forms …
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Eimear N Rutherford, Dawei Sun, Kyungtae Lim, Chris Godbehere et autres
Alveolar type 2 (AT2) cell dysfunction is key to the development of many lung diseases including pulmonary fibrosis (PF). The underlying mechanisms often remain poorly understood due to a paucity of manipulable primary human models and lack of defined triggers. Monogenic forms …
Matthew G. Jones, Dawei Sun, Kyung Hoi Min, William Colgan et autres
Code & scripts for reproducing spatial-lineage analyses in Jones, Sun et al, "Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumour growth and metastasis" 2026. Cassiopeia codebase used for processing lineage data and reconstructing trees. Code for reproducing all analyses in …
us, il (code pays fourni par la source)
Matthew G. Jones, Dawei Sun, Kyung Hoi Min, William Colgan et autres
Code & scripts for reproducing spatial-lineage analyses in Jones, Sun et al, "Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumour growth and metastasis" 2026. Cassiopeia codebase used for processing lineage data and reconstructing trees. Code for reproducing all analyses in …
us, il (code pays fourni par la source)
A Vazquez, Daisy A. Hoagland, Alexander O. Mann, Yunkang Lin et autres
Abstract Lung repair in response to viral infection requires integrated communication between epithelial and immune compartments, yet the impact of antiviral mediators on epithelial regenerative capacity remains poorly defined. Here, we demonstrate that type I interferon (IFN-I) signaling primes the lung for …
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Min Dai, Tivadar Torok, Dawei Sun, Gordon Fishell et autres
This repository contains benchmark and processed datasets for LARIS. It includes simulated spatial transcriptomics datasets for benchmarking, processed outputs from human tonsil Slide-tags data, and processed outputs from developing mouse cortex Stereo-seq data. For details, see the accompanying manuscript: https://www.biorxiv.org/content/10.1101/2025.11.26.690796v1 LARIS enables …
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Min Dai, Tivadar Torok, Dawei Sun, Gordon Fishell et autres
This repository contains benchmark and processed datasets for LARIS. It includes simulated spatial transcriptomics datasets for benchmarking, processed outputs from human tonsil Slide-tags data, and processed outputs from developing mouse cortex Stereo-seq data. For details, see the accompanying manuscript: https://www.biorxiv.org/content/10.1101/2025.11.26.690796v1 LARIS enables …
us (code pays fourni par la source)
Matthew Jones, Dawei Sun, Joseph Min, William Colgan et autres
This repository contains processed data associated with the manuscript "Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumour growth and metastasis" (Jones*, Sun*, et al bioRxiv 2025). In this study, spatially-resolved lineage tracing was performed in the KP autochthonous mouse model …
us, cn (code pays fourni par la source)
Matthew Jones, Dawei Sun, Joseph Min, William Colgan et autres
This repository contains processed data associated with the manuscript "Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumour growth and metastasis" (Jones*, Sun*, et al bioRxiv 2025). In this study, spatially-resolved lineage tracing was performed in the KP autochthonous mouse model …
us, cn (code pays fourni par la source)
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