Accès ouvert
2026
conference-paper
OpenAlex
Svenja Deuchler, Albert J. Augustin, Philipp L. Müller, Friederike Schaub et autres
Zielsetzung: Die intravitreale antiangiogene Therapie stellt den Grundpfeiler im klinischen Management der neovaskulären altersabhängigen Makuladegeneration (nAMD) und des diabetischen Makulaödems (DMÖ) dar. In vielen Regionen Deutschlands wird bei Patienten mit nAMD oder DMÖ [zum vollständigen Text gelangen Sie über die oben angegebene …
de, gb, ch
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2026
article
OpenAlex
Philipp L. Müller, Tim Treis, Robert P Finger, Flora Wicharz et autres
BACKGROUND/AIMS: To evaluate associations of sociodemographic and functional parameters with vision-related quality of life (VRQoL) in recessive Stargardt disease (STGD1). METHODS: A total of 71 participants (42 females, 29 males; mean age 44±19 years) with genetically confirmed STGD1 were included in this …
gb, de, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Clare Bailey, Clemens AK Lange, Marion Rohit Munk, Paolo Lanzetta et autres
The authors acknowledge Anshul Tank, PharmD, an employee of Bayer, for medical writing support for the development of this infographic, in accordance with Good Publication Practice guidelines ( https://www.acpjournals.org/doi/10.7326/M22-1460 ). The authors would also like to acknowledge the principal investigators of the …
gb, de, us, ch, it, ca, au, id, dk, fi, fr, cz
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Accès ouvert
2024
article
OpenAlex
Maximilian Pfau, Jasleen K. Jolly, Jason Charng, Leon von der Emde et autres
Purpose: The purpose of this study was to provide a large, multi-center normative dataset for the Macular Integrity Assessment (MAIA) microperimeter and compare the goodness-of-fit and prediction interval calibration-error for a panel of hill-of-vision models. Methods: Microperimetry examinations of healthy eyes from …
de, ch, gb, us, au
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Maximilian Pfau, Jasleen K. Jolly, Jason Charng, Leon von der Emde et autres
ABSTRACT Purpose To provide a large, multi-center normative dataset for the Macular Integrity Assessment (MAIA) microperimeter and compare the goodness-of-fit and prediction interval calibration-error for a panel of hill-of-vision models. Methods Microperimetry examinations from five independent study groups and one previously available …
ch, gb, au, de
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Accès ouvert
2023
article
OpenAlex
Peter M. Maloca, Maximilian Pfau, Lucas Janeschitz‐Kriegl, Michael Reich et autres
Supervised deep learning (DL) algorithms are highly dependent on training data for which human graders are assigned, for example, for optical coherence tomography (OCT) image annotation. Despite the tremendous success of DL, due to human judgment, these ground truth labels can be …
gb, ch, de, us, es
(code pays fourni par la source)
2023
article
OpenAlex
Philipp L. Müller, Tim Treis, Adnan Tufail, Frank G. Holz
Background/aims To investigate the progression of quantitative autofluorescence (qAF) measures and the potential as clinical trial endpoint inABCA4-related retinopathy. Methods In this longitudinal monocentre study, 64 patients withABCA4-related retinopathy (age (mean±SD), 34.84±16.36 years) underwent serial retinal imaging, including optical coherence tomography (OCT) …
gb, de
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Sonja Eilts, Johanna M. Pfeil, Broder Poschkamp, Tim U. Krohne et autres
Importance: One of the biggest challenges when using anti-vascular endothelial growth factor (VEGF) agents to treat retinopathy of prematurity (ROP) is the need to perform long-term follow-up examinations to identify eyes at risk of ROP reactivation requiring retreatment. Objective: To evaluate whether …
de, us
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Accès ouvert
2022
article
OpenAlex
Roy Schwartz, Hagar Khalid, Sandra Liakopoulos, Yanling Ouyang et autres
Purpose: The purpose of this study was to develop and validate a deep learning (DL) framework for the detection and quantification of reticular pseudodrusen (RPD) and drusen on optical coherence tomography (OCT) scans. Methods: A DL framework was developed consisting of a …
gb, nl, Égypte, de, us, au
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Accès ouvert
2022
article
OpenAlex
Philipp L. Müller, Yuka Kihara, Abraham Olvera‐Barrios, Alasdair Warwick et autres
Purpose: To investigate macular curvature, including the evaluation of potential associations and the dome-shaped macular configuration, given the increasing myopia prevalence and expected associated macular malformations. Methods: The study included a total of 65,440 subjects with a mean age (± SD) of …
gb, de, us
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Accès ouvert
2022
article
OpenAlex
Peter M. Maloca, Christian Freichel, Christof Hänsli, Philippe Valmaggia et autres
Abstract Cynomolgus monkeys exhibit human-like features, such as a fovea, so they are often used in non-clinical research. Nevertheless, little is known about the natural variation of the choroidal thickness in relation to origin and sex. A combination of deep learning and …
gb, ch, cl, de
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Abraham Olvera‐Barrios, Yuka Kihara, Yue Wu, Alasdair Warwick et autres
Purpose: To examine whether sociodemographic, and ocular factors relate to optical coherence tomography (OCT)-derived foveal curvature (FC) in healthy individuals. Methods: We developed a deep learning model to quantify OCT-derived FC from 63,939 participants (age range, 39-70 years). Associations of FC with …
gb, us, de
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