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Profil bibliographique

Victor C. W. Tsang

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

197Publications signalées
13660Citations signalées
0Affiliations récentes

Les domaines associés

Parasitic infections in humans and animalsCongenital Anomalies and Fetal SurgeryParasites and Host InteractionsParasitic Infections and DiagnosticsParasite Biology and Host Interactions

Les publications récentes

Accès ouvert 2019 article OpenAlex

Albendazole Sulfoxide Plasma Levels and Efficacy of Antiparasitic Treatment in Patients With Parenchymal Neurocysticercosis

Gianfranco Arroyo, Javier Arturo Bustos, Andrés G. Lescano, Isidro Gonzáles et autres

BACKGROUND: The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable among patients. We hypothesized that high ASOX plasma levels during albendazole therapy may be …

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19 citations Clinical Infectious Diseases
Accès ouvert 2018 article OpenAlex

Clustering of Necropsy-Confirmed Porcine Cysticercosis Surrounding Taenia solium Tapeworm Carriers in Peru

Andrés G. Lescano, Ian Wright Pray, Armando Emiliano Gonzalez, Robert H. Gilman et autres

The pork tapeworm, Taenia solium, is among the leading causes of preventable epilepsy in the world and is common in rural areas of developing countries where sanitation is limited and pigs have access to human feces. Prior studies in rural villages of …

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24 citations American Journal of Tropical Medicine and Hygiene
Accès ouvert 2017 article OpenAlex

Porcine Cysticercosis: Possible Cross-Reactivity of Taenia hydatigena to GP50 Antigen in the Enzyme-Linked Immunoelectrotransfer Blot Assay

Claudio Muro, Luis Antonio Gomez-Puerta, Robert H. Flecker, Ricardo Gamboa et autres

The lentil lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB, reported sensitivity 99% and specificity 100%) is used as a serologic marker of exposure to Taenia solium in pigs. However, only a limited number of parasites have been evaluated for cross reactivity. Pigs …

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22 citations American Journal of Tropical Medicine and Hygiene
Accès ouvert 2017 article OpenAlex

Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients With Neurocysticercosis

Gianfranco Arroyo, Silvia Rodríguez, Andrés G. Lescano, Karen Ann Alroy et autres

Background: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervous system (CNS), and patients with a single viable …

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33 citations Clinical Infectious Diseases
Accès ouvert 2016 article OpenAlex

High Prevalence of Asymptomatic Neurocysticercosis in an Endemic Rural Community in Peru

Luz M. Moyano, Seth E. O’Neal, Viterbo Ayvar, Guillermo Gonzálvez et autres

BACKGROUND: Neurocysticercosis is a common helminthic infection of the central nervous system and an important cause of adult-onset epilepsy in endemic countries. However, few studies have examined associations between neurologic symptoms, serology and radiographic findings on a community-level. METHODOLOGY: We conducted a …

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79 citations PLoS neglected tropical diseases
Accès ouvert 2016 article OpenAlex

Elimination of Taenia solium Transmission in Northern Peru

Hector Hugo Garcia, Armando Emiliano Gonzalez, Victor C. W. Tsang, Seth E. O’Neal et autres

BACKGROUND: Taeniasis and cysticercosis are major causes of seizures and epilepsy. Infection by the causative parasite Taenia solium requires transmission between humans and pigs. The disease is considered to be eradicable, but data on attempts at regional elimination are lacking. We conducted …

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144 citations New England Journal of Medicine
Accès ouvert 2015 article OpenAlex

Seizures, cysticercosis and rural‐to‐urban migration: the PERU MIGRANT study

Isidro Gonzáles, J. Jaime Miranda, Silvia Rodríguez, Víctor Miguel Toalombo Vargas et autres

OBJECTIVES: To examine the prevalence of seizures, epilepsy and seropositivity to cysticercosis in rural villagers (cysticercosis-endemic setting), rural-to-urban migrants into a non-endemic urban shanty town and urban inhabitants of the same non-endemic shanty town. METHODS: Three Peruvian populations (n = 985) originally …

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18 citations Tropical Medicine & International Health
2014 book-chapter OpenAlex

Immigrants, Imaging, and Immunoblots: the Emergence of Neurocysticercosis as a Significant Public Health Problem

Peter M. Schantz, Patricia P. Wilkins, Victor C. W. Tsang

Taeniasis, or cysticercosis, caused by Taenia solium (often referred to as the pork tapeworm), is a classical zoonosis which has been recognized since antiquity. Cysticercosis is acquired by ingesting Taenia eggs shed in the feces of a human tapeworm carrier and may …

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146 citations ASM Press eBooks
Accès ouvert 2014 article OpenAlex

Recombinant Protein- and Synthetic Peptide-Based Immunoblot Test for Diagnosis of Neurocysticercosis

John C. Noh, Silvia Rodríguez, Yeuk-Mui Lee, Sukwan Handali et autres

One of the most well-characterized tests for diagnosing neurocysticercosis (NCC) is the enzyme-linked immunoelectrotransfer blot (EITB) assay developed at the CDC, which uses lentil lectin-bound glycoproteins (LLGP) extracted from Taenia solium cysticerci. Although the test is very reliable, the purification process for …

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62 citations Journal of Clinical Microbiology
Accès ouvert 2014 article OpenAlex

Neurocysticercosis as a Cause of Epilepsy and Seizures in Two Community-Based Studies in a Cysticercosis-Endemic Region in Peru

Luz M. Moyano, Mayuko Saito, Silvia Maria Montano, Guillermo Gonzálvez et autres

BACKGROUND: The prevalence of epilepsy added to inadequate treatment results in chronic morbidity and considerable mortality in poor populations. Neurocysticercosis (NCC), a helminthic disease of the central nervous system, is a leading cause of seizures and epilepsy in most of the world. …

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103 citations PLoS neglected tropical diseases
Accès ouvert 2013 article OpenAlex

Parasite Antigen in Serum Predicts the Presence of Viable Brain Parasites in Patients With Apparently Calcified Cysticercosis Only

Alonso Zea Vera, Erika G. Cordova-Ramos, Silvia Rodríguez, Isidro Gonzáles et autres

BACKGROUND: Computed tomography (CT) remains the standard neuroimaging screening exam for neurocysticercosis, and residual brain calcifications are the commonest finding. Magnetic resonance imaging (MRI) is more sensitive than CT but is rarely available in endemic regions. Enzyme-linked immunoelectrotransfer blot (EITB) assay uses …

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38 citations Clinical Infectious Diseases
Accès ouvert 2013 article OpenAlex

Relationship between Serum Antibodies and Taenia solium Larvae Burden in Pigs Raised in Field Conditions

Cesar Miguel Gavidia, Manuela Verástegui, Hector Hugo Garcia, María Teresa Rugeles López et autres

BACKGROUND: Serological tests have been used for the diagnosis of Taenia solium infection in pigs. However, those serological results do not necessarily correlate with the actual infection burden after performing pig necropsy. This study aimed to evaluate the Electro Immuno Transfer Blot …

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33 citations PLoS neglected tropical diseases

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