David Paterson

Multimodal imaging reveals no evidence for magnetite-based magnetoreceptors in the mole-rat eye

Leif Moritz‍, Kamalika Nath, Ella P. Walsh, Anna Sternberg et autres

Magnetoreception is widespread across animals, but its sensory mechanism remains unresolved. One leading hypothesis proposes that single-domain magnetite is coupled to mechanosensitive ion channels. In subterranean Ansell's mole-rats, such receptors have been proposed to reside in the cornea or retina. We screened …

de, in, au, at, ch, fr (code pays fourni par la source)

Mobility of rare earth elements in fluid-mineral interactions: europium and cerium speciation in hydrothermally synthesized sulfate and sulfide minerals

Weihua Liu, Yuan Mei, Colin M. MacRae, Alexander M. Glenn et autres

Understanding the incorporation of rare earth elements (REE) into their principal host minerals is fundamental to tracing geological processes, improving ore deposit formation models, assessing the resource potential of a deposit, and designing effective and environmentally sustainable extraction processes. This study investigates …

au (code pays fourni par la source)

Emerging resistance to novel β-lactam β-lactamase inhibitor combinations in Klebsiella pneumoniae bearing KPC variants

Mase Hamza, German Matias Traglia, Lucía Maccari, Sonia Alejandra Gomez et autres

OBJECTIVE: Klebsiella pneumoniae carbapenemase (KPC) variants, predominantly KPC-2 and KPC-3, are significant global resistance mechanisms, conferring resistance to many β-lactams, including carbapenems, while remaining susceptible to ceftazidime-avibactam (CZA). Recently, new KPC variants have developed resistance to CZA through mutations, insertions, or deletions …

us, uy, ar, sg (code pays fourni par la source)

Novel Holographic Spectroscopy for First Determination of Complex Atomic Fine Structure

Chanh Q. Tran, Tony Kirk, Paul Di Pasquale, Minh Dao et autres

au (code pays fourni par la source)

Emerging Resistance to Novel -βLactam β-Lactamase Inhibitor Combinations in Klebsiella pneumoniae bearing KPC Variants

Mase Hamza, German Matias Traglia, Lucía Maccari, Sonia Alejandra Gomez et autres

ABSTRACT Background: Klebsiella pneumoniae carbapenemase (KPC) variants, predominantly KPC-2 and KPC-3, are significant global resistance mechanisms. KPC-2 and KPC-3 confer resistance to a broad range of β-lactams, including carbapenems, while remaining susceptible to ceftazidime-avibactam (CZA). Recently, new KPC variants have developed resistance …

us, uy, ar, sg (code pays fourni par la source)

Mapping nano- and microporosity in ductile shear zones with X-ray ptychography

Nicole M. Bishop, Christoph Eckart Schrank, Michael L. Jones, Cameron M. Kewish et autres

Petrological and geochemical evidence demonstrates that mylonitic ductile shear zones transport significant amounts of fluids through the lithosphere. Because of the lack of percolating pore networks in exhumed mylonitic rocks, it has been hypothesised that most of the fluid pathways in ductile …

au, ch (code pays fourni par la source)

Nanopores enable fluid flux in mylonites and ultramylonites – novel insights from Scanning Small-angle X-ray Scattering and X-ray Fluorescence Microscopy

Christoph Eckart Schrank, Nicole M. Bishop, Michael W. Jones, Alfons Berger et autres

Mylonitic shear zones funnel significant amounts of fluids through the crust. However, the physical mechanisms and pathways for mass transfer remain debated. Grain boundaries, creep cavities, and pores formed by mineral reactions involving volume change and mass transport are considered the most …

au, ch (code pays fourni par la source)

P-157. Molecular epidemiology of carbapenemase genes among carbapenem-resistant Klebsiella pneumoniae (CR-Kp) from the Philippines: implications for surveillance and treatment

Edsel Maurice T. Salvaña, Jonnel B. Poblete, Christian Francisco, Stessi G. Geganzo et autres

Abstract Background In the Philippines, the proportion of carbapenem-resistant Klebsiella pneumoniae (CR-Kp) has doubled in the past decade and now exceeds 15%. However, the prevalence of different carbapenemase genes remains unknown. Unlike the United States and China where blaKPC predominates, blaOXA-48-like serine …

ph, us, au (code pays fourni par la source)

CO 2 storage site CO 2 SO 2 NO X O 2 reactions and metal mobilisation

Julie K. Pearce, Grant Dawson, Frank Brink, Nick Hall et autres

Emulating a Target Trial of Early Compared to Late Initiation of Appropriate Antibiotic Therapy for Hospital-acquired Monobacterial Gram-negative Blood Stream Infections

Abdullah Tarık Aslan, Yukiko Ezure, Elif Seren Tanrıverdi, Osman Dağ et autres

BACKGROUND: Delays in appropriate antimicrobial therapy can increase the risk of all-cause mortality (ACM) in hospital-acquired bloodstream infections (HA-BSIs) caused by Gram-negative bacteria (GNB). We aimed to evaluate the effectiveness of early appropriate antimicrobial therapy (EAAT) compared with late appropriate antimicrobial therapy …

au, tr, be, sg (code pays fourni par la source)

Establishing clinical research networks for future infectious disease outbreak responses in Southeast Asia: Report of a workshop on challenges and opportunities

Su Myat Han, Yin Mo, Lin‐Fa Wang, David Chien Lye et autres

The COVID-19 pandemic highlighted the critical need for well-established clinical research networks capable of rapid response during infectious disease outbreaks. In Southeast Asia, the absence of active research networks at the onset of the COVID-19 contributed to gaps in regional preparedness. This …

us, sg (code pays fourni par la source)

Non-destructive visualisation and in situ quantification of micronutrient mobilisation in germinating rice grains using synchrotron-based X-ray fluorescence microscopy

Qurrat ul Ain, David Paterson, Rosalie K. Hocking, Mrinal R. Bhave et autres

Maintaining micronutrient availability in germinating rice tissues is crucial for seedling vigour and agronomic performance. However, current methods for visualising micronutrient dynamics often require destructive sample preparation. Here we report that synchrotron-based X-ray fluorescence microscopy (XFM) could enable non-destructive, in situ visualisation …

au (code pays fourni par la source)