Xingyu Guo

Effect of Repeated Heat–Moisture Treatment Temperature on the Multi-Scale Structure, Physicochemical Properties, Rheological Behavior, and In Vitro Digestibility of Hard Proso Millet Starch

Meiqi Dong, Daiyan Chao, Yajing Cao, Xingyu Guo et autres

Repeated heat–moisture treatment (RHMT) is an efficient approach for modifying starch. However, the role of treatment temperature, a critical parameter, remains poorly understood. Therefore, this study investigated the effects of RHMT temperatures (80, 100, 120 °C) and cycles (1, 3, 5, 7) …

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Research Progress of Traditional Chinese Medicine Intervention in Postoperative Pain after Mixed Hemorrhoid Surgery

Xingyu Guo, Jin Zeng

Mixed hemorrhoids are common and frequently encountered diseases in anorectal surgery. Although surgery can effectively remove the lesions, postoperative pain remains an important issue affecting patients’ recovery experience and the quality of wound healing. Its occurrence is closely associated with the rich …

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Research Progress of Traditional Chinese Medicine Intervention in Postoperative Pain after Mixed Hemorrhoid Surgery

Xingyu Guo, Jin Zeng

Mixed hemorrhoids are common and frequently encountered diseases in anorectal surgery. Although surgery can effectively remove the lesions, postoperative pain remains an important issue affecting patients’ recovery experience and the quality of wound healing. Its occurrence is closely associated with the rich …

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Multi-dimensional information characterization of different grades of Atractylodis macrocephalae Rhizoma based on HS-GC–MS, LC–MS, electronic nose, and electronic tongue

Ruiqi Yang, Yushi Wang, Jiayu Wang, Ziyue Song et autres

in Chinese) is used in traditional Chinese medicine (TCM) for treating gastrointestinal disorders, such as diarrhea and gastritis. With increasing demand, its cultivation areas have expanded significantly. However, the quality of AMR varies considerably by geographical origin and commercial grades, and current …

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A Novel Strategy for Rapid Quantification of Multiple Quality Indicators and Grade Discrimination of Atractylodis macrocephalae Rhizoma Based on Electronic Nose, Electronic Tongue and Machine-Learning Algorithms

Ruiqi Yang, Jiayu Wang, Yushi Wang, Xingyu Guo et autres

Atractylodes macrocephala Rhizoma (AMR) is a frequently used medicinal herb for treating gastrointestinal disorders, with its quality influenced by factors such as origin and cultivation duration. Traditional quality control methods for AMR are time-consuming and invasive, making the development of faster and …

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Machine Learning Modeling for Codonopsis Radix Quality Assessment Integrating Efficacy, Chemical Composition, and Macroscopic Traits

Xingyu Guo, Ziyue Song, Yifan Sun, Chi Wang et autres

samples from six origins were grouped based on pharmacological and chemical indicators, integrating pharmacodynamic evaluations using impaired spleen and lung function animal models with compositional analysis of the alcohol-soluble extract and polysaccharide contents. Subsequently, an electronic nose was employed to objectively quantify …

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Mitochondrial dysfunction and AMPK-associated metabolic reprogramming in zebrafish exposed to fluorinated liquid crystal monomers

Junjie Wang, Siying Ma, Siyi Li, Shan He et autres

Fluorinated liquid crystal monomers (FLCMs), emerging contaminants from electronic waste, exhibit environmental persistence and bioaccumulative potential. Despite their growing detection in humans and aquatic systems, the subcellular mechanisms of their metabolic toxicity remain poorly understood. Here, zebrafish (Danio rerio) embryos and larvae …

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Mendelian randomization and bioinformatics analysis identify the association between plasma proteins and cataract

Xuan Han, Jinyan Wang, Xiaojuan Su, Xingyu Guo et autres

Previous observational studies have indicated a significant correlation between plasma proteome composition and cataract pathological status; however, the direction of causality remains uncertain. In light of the aforementioned findings, the present study employs a bidirectional two-sample Mendelian randomisation strategy, with the objective …

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Pharmacological action, mechanism and structure-activity relationship of traditional Chinese medicine polysaccharide in the treatment of Alzheimer's disease: A review

Xingyu Guo, Wenting Yu, Hai‐Zhi Bu, Yongqiang Du et autres

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Metabolic Reprogramming of Gastric Cancer Revealed by a Liquid Chromatography–Mass Spectrometry-Based Metabolomics Study

Zhou Lina, Benzhe Su, Zexing Shan, Zhenbo Gao et autres

BACKGROUND/OBJECTIVES: Gastric cancer (GC) is a prevalent malignant tumor worldwide, with its pathological mechanisms largely unknown. Understanding the metabolic reprogramming associated with GC is crucial for the prevention and treatment of this disease. This study aims to identify significant alterations in metabolites …

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Metabolite biomarkers of screening neonatal congenital hypothyroidism based on dried blood spot metabolomics

Xingyu Guo, Feng Suo, Yuting Wang, Di Yu et autres

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Exploring the causal influence of 731 immune cells on 4 different glaucoma subtypes using a two-sample mendelian randomization method

Xuan Han, Jinyan Wang, Xiaojuan Su, Xingyu Guo et autres

In the pathological progression of glaucoma, damage to the ocular nerves and associated tissue alterations can induce a systemic immune response, leading to the activation of various immune cells such as T cells, B cells, and macrophages. This complex process has the …

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