Yukun Yang

Pro-resolving lipid mediators in diseases: exploring the molecular basis and clinical implication

Chaofu Li, Yukun Yang, Yingying Jiang, Yingying Jiang et autres

Inflammation resolution is now understood as an active and highly coordinated biological process rather than a passive decline in inflammatory signals. When this program fails, inflammation may become persistent and gradually shift to a chronic pathological state. Such unresolved inflammation is increasingly …

cn, de (code pays fourni par la source)

Fake News Detection in Short Videos by Integrating Semantic Credibility and Multi-Granularity Contrastive Learning

Yukun Yang, Haoxu Li, Yijia Xu

Short videos have become a primary medium for news delivery, but their low cost, rapid diffusion, and multimodal nature make misinformation easier to generate and harder to verify. Existing methods often rely on single-modality cues or shallow cross-modal correlations, making it difficult …

cn (code pays fourni par la source)

A two-stage transdermal drug delivery system comprising sono-phase-change transfersomes for non-invasive deep dermal delivery

Yi Zhang, Xiong He, Xiang Mao, Yukun Yang et autres

Non-invasive deep transdermal drug delivery is required for conditions such as keloids. However, the skin's stratum corneum barrier is the primary obstacle for transdermal drug delivery methods. Most energy sources and operational controls are located externally, making it difficult to regulate the …

cn (code pays fourni par la source)

N-doped HOFs nanoenzymes enable dual-mode colorimetric/electrochemical aptasensing of AFB1

Lanqing Yang, Qing Li, Baoqing Bai, Bo Tao et autres

Aflatoxin B1 (AFB1), a highly toxic mycotoxin prevalent in agricultural products, poses severe health threats. Addressing the critical need to mitigate AFB1-induced food safety risks, the primary objective of this study was to develop an accurate and ultrasensitive colorimetric/electrochemical (CL/EC) dual-mode aptasensor …

cn (code pays fourni par la source)

MFN2 and BAG6 Synergistically Protect Against Cerebral Reperfusion Injury by Regulating ROS Levels and Autophagic Flux

Danbo Lu, Yukun Yang, Guodong Huang, Qinlian Ye et autres

BACKGROUND: MFN2 (mitofusin-2), a transmembrane dynamin-like protein located on the outer mitochondrial membrane, plays a key role in regulating mitochondrial fusion and autophagy. In vitro studies suggested that MFN2 may exert neuroprotective effects postischemia. In gain-of-function and loss-of-function experiments, we investigated MFN2'·s …

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Noninvasive and Precise Transdermal Drug Delivery Using Spatiotemporally Responsive Lipid Vesicles in Conjunction with Ultrasound

Zhenyu Wang, Jiayu Zhang, Yukun Yang, Haixiang Chen et autres

Transdermal drug delivery (TDD) is influenced by the multiple anatomical layers of skin and various barriers, making the precise delivery of multiple drugs to specific spatial locations for optimal therapeutic efficacy a challenging prospect. This study proposes a strategy involving the use …

cn (code pays fourni par la source)

Shear Behavior of Composite Beams With Open‐Web π‐Shaped Steel Partially Encased by Concrete

Yunhui Chen, Liusheng Chu, Jie Li, Yukun Yang

ABSTRACT Partially encased composite (PEC) structure, easily prefabricated and assembled, is widely used in prefabricated construction. To improve the web utilization and the productivity of the PEC structure, a new PEC beam with open‐web π‐shaped steel is proposed in this paper. Notably, …

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Experimental study on the shear strength of partially-encased composite beams with corrugated webs

Liusheng Chu, Jingjing Zhao, Yuexi He, Jie Li et autres

The partially-encased composite beam with a corrugated web (CWPEC) is an improved composite member, which combines the respective advantages of traditional partially-encased composite beams and corrugated web beams. However, understanding on the shear performance of such beams is still quite limited, leading …

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The Tenth NTIRE 2025 Efficient Super-Resolution Challenge Report

Bin Ren, Hang Guo, Lei Sun, Zongwei Wu et autres

This paper presents a comprehensive review of the NTIRE 2025 Challenge on Single-Image Efficient Super-Resolution (ESR). The challenge aimed to advance the development of deep models that optimize key computational metrics, i.e., runtime, parameters, and FLOPs, while achieving a PSNR of at …

it, cn, bg, de, ch (code pays fourni par la source)

Autophagy hub-protein p62 orchestrates oxidative, endoplasmic reticulum stress, and inflammatory responses post-ischemia, exacerbating stroke outcome

Xingyun Quan, Yukun Yang, Xiaolong Liu, Britta Kaltwasser et autres

Autophagy has crucial roles for ischemia/reperfusion (I/R) injury. To define the role of the autophagy hub protein p62/SQSTM1 in I/R injury, we conducted gain-of-function and loss-of-function experiments in a set of cell types, including two neuron-like cell lines, primary neurons, brain endothelial …

de (code pays fourni par la source)

The Tenth NTIRE 2025 Efficient Super-Resolution Challenge Report

Bin Ren, Hang Guo, Lei Sun, Zongwei Wu et autres

This paper presents a comprehensive review of the NTIRE 2025 Challenge on Single-Image Efficient Super-Resolution (ESR). The challenge aimed to advance the development of deep models that optimize key computational metrics, i.e., runtime, parameters, and FLOPs, while achieving a PSNR of at …

Activation of the PERK Branch of the UPR as a Strategy for Improving Outcomes in Acute Ischemic Stroke

Xiangzhu Li, Danbo Lu, Lei Zou, Lijuan Ma et autres

Brain ischemia disrupts endoplasmic reticulum (ER) dynamics, causes ER stress, and triggers the unfolded protein response (UPR). During the UPR, protein kinase RNA-like ER kinase (PERK) phosphorylates eIF2α, shutting down global protein synthesis, inhibits protein synthesis, and provides neuroprotection during acute ischemic …

cn, de, Égypte (code pays fourni par la source)