Yang Song

Epidemiological characteristics of Group A rotavirus diarrhea in children under 5 years old in China from 2009 to 2020

Xu Ding, Li Cai, Jiayi Zhang, Yang Song et autres

BACKGROUND: Group A rotavirus (RVA) is a leading cause of childhood diarrhea globally. Despite its status as a reportable infectious diarrhea in China, comprehensive and specific national RVA surveillance data remain scarce. This study analyzed the National Science and Technology Major Project …

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NADK Governs Ferroptosis Susceptibility by Orchestrating NADPH Homeostasis

Xinyi Chen, Yingying Zhang, Dandan Song, Fei Gui et autres

Ferroptosis, a regulated cell death pathway driven by iron-dependent lipid peroxidation, is modulated by cellular antioxidant systems, particularly the glutathione (GSH)–glutathione peroxidase 4 (GPX4) axis. NAD kinase (NADK), the only enzyme converting NAD+ to NADP+ located in cytoplasm, fuels NADPH-dependent antioxidant defenses. …

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Investigating the Microbiota-Gut-Brain Axis Mechanisms of Transcutaneous Auricular Vagus Nerve Stimulation in Patients with Obesity: A Study Protocol for a Randomized Controlled Trial

Xia Chen, Weiqing Kong, Yang Song, Wei Huang et autres

Background: Obesity is a common metabolic disorder affecting nearly one-third of the global population. Emerging evidence indicates that the microbiota-gut-brain axis plays a key role in the pathogenesis of obesity. Transcutaneous auricular vagus nerve stimulation (taVNS), a non-invasive neuromodulation technique, may modulate …

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First identification of Tusavirus in calf intestinal tissue suggests interspecies transmission and genomic variation

Yang Song, Weiwei Gai, Jiaxin Sun, Xiangyu Lv et autres

• This is the first identification of Tusavirus in calf tissue in China, expanding its host species and geographical range. • Genomic analysis revealed conservation, with nucleotide insertions in the VP1 gene and deletions in both VP1 and VP2 genes.

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Latency-Associated Nuclear Antigen (LANA) Promotes Ferroptosis by Suppressing Nrf2/GPX4 and Upregulating MDM2

Yuejia Cao, Shihan Shao, Yingying Zhang, Dandan Song et autres

Ferroptosis, an iron-dependent cell death driven by lipid peroxidation, is regulated by key mediators including glutathione peroxidase 4 (GPX4) and nuclear factor erythroid 2-related factor 2 (Nrf2). Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes latency-associated nuclear antigen (LANA), a multifunctional protein critical for viral …

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Correction: Guo et al. A Mixture of T-Cell Epitope Peptides Derived from Human Respiratory Syncytial Virus F Protein Conferred Protection in DR1-TCR Tg Mice. Vaccines 2024, 12, 77

Hong Guo, Yang Song, Hai Li, Hongqiao Hu et autres

The authors would like to make the following corrections to this published paper [...].

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The impact of research funding on academic outputs: Evidence from the personnel data in China

Yang Song, Wenkai Sun, Yufei Zhang

This paper is one of the first attempts that analyse the ­effectiveness of national research funding based on personnel data in ­developing countries. We employ the personnel data from 1998 to 2015 in the field of economics and management of a prestigious …

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Latency-associated nuclear antigen (LANA) promotes ferroptosis by suppressing Nrf2 and upregulating MDM2

Yuejia Cao, Shihan Shao, Yingying Zhang, Dandan Song et autres

Ferroptosis is a recently discovered iron-dependent form of programmed cell death, characterized by the accumulation of lipid peroxidation. Latency-associated nuclear antigen (LANA) plays a crucial role in ensuring the survival and proliferation of cells infected with Kaposi’s sarcoma-associated herpesvirus (KSHV). In this …

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Evolution, recombination and geographic spreading of global Coxsackievirus A6

Huanhuan Lu, Jinbo Xiao, Yang Song, Dongmei Yan et autres

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Effectiveness of Enterovirus 71 inactivated vaccines against hand, foot, and mouth disease: A test-negative case-control study

Yutong Zhang, Jinzhao Cui, Fengfeng Liu, Yang Song et autres

The Enterovirus A71 (EV-A71) vaccine was introduced in China in December 2015 as a preventive measure against hand, foot, and mouth disease (HFMD) caused by EV-A71. However, the effectiveness of the vaccine (VE) in real-world settings needs to be evaluated. We conducted …

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Identification and genetic characterization of a recently identified enterovirus C116 in China

Zhenzhi Han, Jichen Li, Jinbo Xiao, Huanhuan Lu et autres

Enterovirus C116 (EV-C116) is a new member of the enterovirus C group which is closely associated with several infectious diseases. Although sporadic studies have detected EV-C116 in clinical samples worldwide, there is currently limited information available. In this study, two EV-C-positive fecal …

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Genotype F of Echovirus 25 with multiple recombination pattern have been persistently and extensively circulating in Chinese mainland

Xiaoyi Wang, Jianping Cun, Shikang Li, Yong Shi et autres

Abstract Echovirus 25 (E25), a member of the Enterovirus B (EV-B) species, can cause aseptic meningitis (AM), viral meningitis (VM), and acute flaccid paralysis (AFP). However, systematic studies on the molecular epidemiology of E25, especially those concerning its evolution and recombination, are …

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