Accès ouvert
2025
article
OpenAlex
Guotao Ding, Mengyu Liu, Yanfei Fang, Peng Sun et autres
Cicadas are a traditional food in China. In this study, we performed multielement analysis on cicadas using Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). In total, 40 cicada samples were collected in Hebei Province (China). Comparing the results of mushroom and vegetable samples selected …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Zeyu Chen, Morgan Dragan, Peng Sun, Daniel Haensel et autres
The skin is our outer permeability and immune defense barrier against myriad external assaults. Aryl hydrocarbon receptor (AhR) senses environmental factors and regulates barrier robustness and immune homeostasis. AhR agonists have been approved by the FDA for psoriasis treatment and are in …
cn, us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Peng Sun, Zhenfeng Li, Zaojun Yan, Zhaofeng Wang et autres
Lenvatinib, a multitarget kinase inhibitor, has been proven to be effective in the treatment of advanced hepatocellular carcinoma. It has been previously demonstrated that tumour associated macrophages (TAMs) in tumour tissues can promote HCC growth, invasion and metastasis. Furthermore, lenvatinib has certain …
cn
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Zeyu Chen, Morgan Dragan, Peng Sun, Daniel Haensel et autres
ABSTRACT Skin is our outer permeability and immune defense barrier against myriad external assaults. Aryl hydrocarbon receptor (AhR) senses environmental factors and regulates barrier robustness and immune homeostasis. AhR agonist is in clinical trial for atopic dermatitis (AD) treatment, but the underlying …
cn, us
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Peng Sun, Zhenfeng Li, Zaojun Yan, Zhaofeng Wang et autres
Abstract Lenvatinib, a multi-target kinase inhibitor, has been proven to be effective in the treatment of advanced hepatocellular carcinoma. It has been previously demonstrated that tumor associated macrophages (TAMs) in tumor tissues could promote HCC growth, invasion and metastasis. Furthermore, the lenvatinib …
cn, us, gb
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Morgan Dragan, Zeyu Chen, Yumei Li, Johnny Le et autres
Skin epidermis constitutes the outer permeability barrier that protects the body from dehydration, heat loss, and myriad external assaults. Mechanisms that maintain barrier integrity in constantly challenged adult skin and how epidermal dysregulation shapes the local immune microenvironment and whole-body metabolism remain …
us
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Remy Vu, Suoqin Jin, Peng Sun, Daniel Haensel et autres
Delayed and often impaired wound healing in the elderly presents major medical and socioeconomic challenges. A comprehensive understanding of the cellular/molecular changes that shape complex cell-cell communications in aged skin wounds is lacking. Here, we use single-cell RNA sequencing to define the …
us, cn
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Guadalupe Gutierrez, Peng Sun, Yingying Han, Xing Dai
Breast cancer is a heterogenous disease that can be classified into multiple subtypes including the most aggressive basal-like and triple-negative subtypes. Understanding the heterogeneity within the normal mammary basal epithelial cells holds the key to inform us about basal-like cancer cell differentiation …
us
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Meng Qi, Xiuyun Duan, Qingchao Yang, Dewen Xue et autres
Tumor‑associated macrophages (TAMs) are capable of worsening hepatocellular carcinoma (HCC) prognosis by accelerating tumor growth and progression. Signaling lymphocyte activation molecule family member 6 (SLAMF6; Ly108 in mice) is an immune regulator that is involved in numerous diseases. However, whether SLAMF6 might …
cn
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Yingying Han, ALVARO P. VILLARREAL-PONCE, Guadalupe Gutierrez, Quy Nguyen et autres
Maintenance of undifferentiated, long-lived, and often quiescent stem cells in the basal compartment is important for homeostasis and regeneration of multiple epithelial tissues, but the molecular mechanisms that coordinately control basal cell fate and stem cell quiescence are elusive. Here, we report …
us, cn, be, de, jp
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Melissa McNeil, Yingying Han, Peng Sun, Kazuhide Watanabe et autres
Mammary gland is an outstanding system to study the regulatory mechanisms governing adult epithelial stem cell activity. Stem cells in the basal layer of the mammary gland fuel the morphogenesis and regeneration of a complex epithelial network during development and upon transplantation. …
us, cn
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Peng Sun, Yingying Han, Maksim V. Plikus, Xing Dai
Stem-cell containing mammary basal epithelial cells exist in a quasi-mesenchymal transcriptional state characterized by simultaneous expression of typical epithelial genes and typical mesenchymal genes. Whether robust maintenance of such a transcriptional state is required for adult basal stem cells to fuel self-renewal …
us
(code pays fourni par la source)