Young‐Mi Kim

Partial Deletion of the Carboxyl‐Terminal Signal Sequence of the Cellular Prion Protein Alters Protein Expression via Endoplasmic Reticulum–Associated Degradation

Miryeong Yoo, Sung‐Eun Lee, Jieun Kim, Sunyeong Cha et autres

ABSTRACT Cellular prion protein (PrP C ) is a glycoprotein tethered to the plasma membrane via a GPI‐anchor, and it plays a crucial role in prion diseases by undergoing conformational change to PrP Sc . To generate a knock‐in (KI) mouse model …

kr, vn (code pays fourni par la source)

A Human-Centered Approach to Methodologies for AI-Generated Human Imagery

Changsheng Wang, Young‐Mi Kim

인공지능(AI)의 급속한 발전은 예술 창작에서 AI를 중요한 도구로 자리 매김하게 했다. 미드저니(Midjourney)와 같은 AI 그림 모델은 간단한 텍스 트 입력만으로 고품질 이미지를 생성할 수 있다. 컴퓨터의 기술 예술 창 작 방식에 변화는 다양하게 이루어지고 있다. 예술과 기술을 접목시키는 기계적 상황은 ‘인간적 접근 …

Scirpus planiculmis Extract Inhibits the Activation of Syk to Suppress Mast Cell-mediated Allergic Responses in vitro and in vivo

Young‐Mi Kim

Scirpus planiculmis (SP) has been used for a long time as a traditional therapy to cure bronchiectasis, gynecopathy, chest pain, and dyspepsia in Asian countries. However, the therapeutic effect of SP on allergic diseases remains to be determined. In this study, we …

Abstract A039: Repeat RNA mediated disruption of cellular plasticity in pancreatic cancer

Eunae You, Patrick Danaher, Chenyue Lu, Siyu Sun et autres

Abstract Aberrant expression of repeat RNAs in pancreatic ductal adenocarcinoma (PDAC) mimics viral-like responses with implications for tumor cell state and the surrounding microenvironment. To better understand the relationship of repeat RNAs in human PDAC, we employed the NanoString CosMx™ spatial molecular …

us (code pays fourni par la source)

Dihydrostilbenes and flavonoids from whole plants of Jacobaea vulgaris

Shinae Lee, Min-Gyung Son, Young‐Mi Kim, Chae-Yeong An et autres

kr, mn, pr (code pays fourni par la source)

Chlorophyll a and novel synthetic derivatives alleviate atopic dermatitis by suppressing Th2 cell differentiation via IL-4 receptor modulation

Koon Mook Kang, Jung-Hyun Han, Kyeong Seok Kim, Eun‐Kyung Kim et autres

kr (code pays fourni par la source)

Stereochemical assignment of clerodane-type diterpenes from the fruits of Casearia grewiifolia and their ability to inhibit PCSK9 expression

Piseth Nhoek, Chae-Yeong An, Min-Gyung Son, Hee‐Sung Chae et autres

kr, kh, pr (code pays fourni par la source)

Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease

Alba Garrido-Trigo, A M Corraliza, Marisol Veny, Isabella Dotti et autres

Ulcerative colitis and Crohn's disease are chronic inflammatory intestinal diseases with perplexing heterogeneity in disease manifestation and response to treatment. While the molecular basis for this heterogeneity remains uncharacterized, single-cell technologies allow us to explore the transcriptional states within tissues at an …

es, ch, us (code pays fourni par la source)

An information theoretic approach to detecting spatially varying genes

Daniel C. Jones, Patrick Danaher, Young‐Mi Kim, Joseph Beechem et autres

A key step in spatial transcriptomics is identifying genes with spatially varying expression patterns. We adopt an information theoretic perspective to this problem by equating the degree of spatial coherence with the Jensen-Shannon divergence between pairs of nearby cells and pairs of …

us, ch (code pays fourni par la source)

PDAC-SMI transcript locations

Carina Shiau, Jingyi Cao, Dennis Gong, Mark Gregory et autres

This record contains the spatial locations of transcripts in the PDAC-SMI data.

us, jp (code pays fourni par la source)

Supplementary Figure S2 from TC1 (C8orf4) Enhances the Wnt/β-Catenin Pathway by Relieving Antagonistic Activity of Chibby

Yusun Jung, Seunghyun Bang, Kyungho Choi, Eunsoon Kim et autres

Supplementary Figure S2 from TC1 (C8orf4) Enhances the Wnt/β-Catenin Pathway by Relieving Antagonistic Activity of Chibby

Supplementary Figure S1 from TC1 (C8orf4) Enhances the Wnt/β-Catenin Pathway by Relieving Antagonistic Activity of Chibby

Yusun Jung, Seunghyun Bang, Kyungho Choi, Eunsoon Kim et autres

Supplementary Figure S1 from TC1 (C8orf4) Enhances the Wnt/β-Catenin Pathway by Relieving Antagonistic Activity of Chibby