Sunyeong Cha

Partial Deletion of the Carboxyl‐Terminal Signal Sequence of the Cellular Prion Protein Alters Protein Expression via Endoplasmic Reticulum–Associated Degradation

Miryeong Yoo, Sung‐Eun Lee, Jieun Kim, Sunyeong Cha et autres

ABSTRACT Cellular prion protein (PrP C ) is a glycoprotein tethered to the plasma membrane via a GPI‐anchor, and it plays a crucial role in prion diseases by undergoing conformational change to PrP Sc . To generate a knock‐in (KI) mouse model …

kr, vn (code pays fourni par la source)

Usefulness of clustering blood biochemical markers to assess thermal stress and acclimation in red seabream, Pagrus major

Hye‐Jin Jeong, Minji Kang, Sunyeong Cha, Jihyun Byun et autres

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All-in-one platform for salivary cotinine detection integrated with a microfluidic channel and an electrochemical biosensor

Kyungyeon Lee, Taehee Yoon, Heeseon Yang, Sunyeong Cha et autres

, which was in good agreement with that measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The introduced all-in-one platform represented a reliable performance delivering simple and practical steps in salivary diagnostics.

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Chronic and Low Dose Exposure to Nonlyphenol or Di(2-Ethylhexyl) Phthalate Alters Cell Proliferation and the Localization of Steroid Hormone Receptors in Uterine Endometria in Mice

Juhye Kim, Sunyeong Cha, Min Young Lee, Yeon Jeong Hwang et autres

Based on our preliminary results, we examined the possible role of low-dose and chronic-exposing of the chemicals those are known as endocrine disrupting chemical (EDC), on the proliferation of uterine endometrium and the localization of steroid receptors. Immunohistochemical or immunofluorochemical methodology were …

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On-chip isolation and enrichment of circulating cell-free DNA using microfluidic device

Hogyeong Gwak, Junmoo Kim, Sunyeong Cha, Yong‐Pil Cheon et autres

Circulating cell-free DNA (cfDNA), containing cancer-specific DNAs derived from tumor cells, plays an important role in real-time monitoring of disease progression. Due to the abnormal growth of cancer and the promotion of cancer cell apoptosis by chemotherapy, the higher cfDNA concentration than …

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Chronic Low-Dose Nonylphenol or Di-(2-ethylhexyl) Phthalate has a Different Estrogen-like Response in Mouse Uterus

Juhye Kim, Sunyeong Cha, Min Young Lee, Yeon Jeong Hwang et autres

Through the development of organic synthetic skill, chemicals that mimic signaling mediators such as steroid hormones have been exposed to the environment. Recently, it has become apparent that this circumstance should be further studied in the field of physiology. Estrogenic action of …

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Nonmonotonic Effects of Chronic Low-Dose Di(2-ethylhexyl) Phthalate on Gonadal Weight and Reproductive

Sunyeong Cha, Kayeon Jung, Min Young Lee, Yeon Jeong Hwang et autres

Endocrine disruptors have been concerned in toxicology but now challenged as physiological point especially concerned with exposing dose and period. In this study the low-dose chronic administration of di(2-ethylhexyl) phthaltae (DEHP) during reproductive period was examined to evaluate the possible roles. Adult …

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Disturbing Effects of Chronic Low-dose 4-Nonylphenol exposing on Gonadal Weight and Reproductive Outcome over One-generation

Sunyeong Cha, Jeong Won Baek, Hye Jin Ji, Jun Hee Choi et autres

4-Nonylphenol (NP) is a surfactant that is a well-known and widespread estrogenic endocrine disrupting chemical (EDC). Although it has been known that the affinity of NP to ERs is low, it has been suggested that low-dose NP has toxicity. In the present …

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Positive Effects of Diphlorethohydroxycarmalol (DPHC) on the Stability of the Integument Structure in Diet-Induced Obese Female Mice

Chaelim Kim, Sunyeong Cha, Min Young Chun, Bum‐Soo Kim et autres

Diphlorethohydroxycarmalol (DPHC) is a known to modulate the expression of extracellular matrix (ECM) components in 3T3-L1. However, the possible role of DPHC in integument stability during obesity induction is not clear yet. We evaluated the effects of DPHC on collagen or elastic …

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Diphlorethohydroxycarmalol (DPHC) suppresses adipogenesis of integument in obese mouse

Sunyeong Cha, Dong Heon Cho, Bum‐Soo Kim, Min Young Choi et autres

Suppressive Effects of an Ishige okamurae extract on 3T3-L1 Preadipocyte Differentiation

Sunyeong Cha, Yong‐Pil Cheon

The biological activity of tissue specific stem cell is under the control of their specific microenvironment and the exogenous chemicals derived from digestive tract can be one of the constructing factors of that. It is suggested that the extract of brown algae …

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Effect of diphlorethohydroxycarmalol (DPHC) isolated from Ishige okamurae modified the cellular activity and differentiation of 3T3-L1 cell line

Sunyeong Cha, Yong‐Pil Cheon