María Ángela Jure

Role of water as a reservoir of antimicrobial‐resistant Escherichia coli in the environment of Tucumán, Argentina

Juan M. Casa Vargas, Carolina López, Lucia Micale, María Paula Moreno Mochi et autres

Abstract Population growth, industrialization and climate change put continuous pressure on the quality and quantity of water resources. The aim of the present study is to understand the role of aquifers that receive residues from human activity, as a reservoir of antimicrobial‐resistant …

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Notificación de absceso cerebral por Morganella morganii productor de KPC: descripción microbiológica y clínica

Juan M. Casa Vargas, María Paula Moreno Mochi, María Ángela Jure

Morganella morganii es un bacilo anaerobio facultativo gramnegativo, que pertenece a la microbiota comensal intestinal humana que puede adquirir resistencia a múltiples antibiotcs. Presentamos aquí el aislamiento de la cepa de Morganella morganii positiva para blaKPC de un solo paciente y el …

Assessment of hygienic-sanitary status and implementation of an integral risk management program in butcher shops from Tafí Viejo city, Tucumán, Argentina

María Paula Moreno Mochi, Juan M. Casa Vargas, Magdalena Costa, María Gabriela Bravo Solórzano et autres

Meat and meat products promote the growth of pathogens such as Shiga toxin-producing Escherichia coli and Salmonella spp. In this work, an evaluation was carried out through risk quantification and microbiological analysis on ground beef and environmental surfaces in butcher shops, of …

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Safety attributes of Pseudomonas sp. P26, an environmental microorganism with potential application in contaminated environments

Constanza Belén Lobo, Rocío Daniela Inés Molina, Paula Moreno Mochi, Juan M. Casa Vargas et autres

Currently, the selection of non-pathogenic microorganisms that lack clinically relevant antimicrobial resistance is crucial to bioaugmentation strategies. Pseudomonas sp. P26 (P26) is an environmental bacterium of interest due to its ability to remove aromatic compounds from petroleum, but its safety characteristics are …

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Hypermucoviscous Carbapenem-Resistant Klebsiella pneumoniae ST25 Infect Human Intestinal Epithelial Cells and Induce Moderate Inflammation

Stefanía Dentice Maidana, Mariano Elean, Kohtaro Fukuyama, Yoshiya Imamura et autres

Klebsiella pneumoniae is an opportunistic pathogen that can produce moderate and severe infections in immunosuppressed hosts. In recent years, an increase in the isolation of hypermucoviscous carbapenem-resistant K. pneumoniae with sequence type 25 (ST25) in hospitals in Norwest Argentina was observed. This …

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Oral Administration of Lacticaseibacillus rhamnosus CRL1505 Modulates Lung Innate Immune Response against Klebsiella pneumoniae ST25

Stefanía Dentice Maidana, Yoshiya Imamura, Mariano Elean, Leonardo Albarracín et autres

Orally administered Lacticaseibacillus rhamnosus CRL1505 enhances respiratory immunity, providing protection against respiratory viruses and Streptococcus pneumoniae. However, the capacity of the CRL1505 strain to improve respiratory immunity against Gram-negative bacterial infections has not been evaluated before. The aim of this work was …

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Comprehensive evaluation of abattoirs with no Hazard Analysis Critical Control Point plan in Tucumán, Argentina

Gabriela Pérez Terrazzino, Magdalena Costa, Alejandro López Campo, Carolina Saade et autres

This work focused on the comprehensive study of two provincial transit abattoirs in Tucumán, Argentina, with no Hazard Analysis Critical Control Point (HACCP) plan. Visits (n = 20) were conducted between 2016 and 2018 during the operational and post-operational processes. Risk was …

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Emergence and clonal spread of KPC-2-producing clinical Klebsiella aerogenes isolates in a hospital from northwest Argentina

Juan M. Casa Vargas, María Paula Moreno Mochi, Juan Manuel Nuñez, Silvana Mochi et autres

Introduction. Klebsiella aerogenes is a nosocomial pathogen associated with drug resistance and healthcare-associated infections. Gap Statement. K. aerogenes is associated with hospital-acquired infections with the ability to acquire mechanisms of resistance to reserve antimicrobials; its clinical behaviour has been poorly documented. Objective. …

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Interactions of Pathogenic Escherichia coli with Gut Microbiota

Elizabeth Sandra Miliwebsky, María Ángela Jure, Mauricio J. Farfán, Marina Sandra Palermo

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Respiratory Commensal Bacteria Increase Protection against Hypermucoviscous Carbapenem-Resistant Klebsiella pneumoniae ST25 Infection

Stefanía Dentice Maidana, Ramiro Ortiz Moyano, Juan M. Casa Vargas, Kohtaro Fukuyama et autres

In a previous work, we demonstrated that nasally administered Corynebacterium pseudodiphtheriticum 090104 beneficially modulated the respiratory innate immune response and improved the protection against Respiratory Syncytial Virus and Streptococcus pneumoniae in mice. In this work, we aimed to evaluate whether the immunomodulatory …

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Genomic and Immunological Characterization of Hypermucoviscous Carbapenem-Resistant Klebsiella pneumoniae ST25 Isolates from Northwest Argentina

Leonardo Albarracín, Ramiro Ortiz Moyano, Juan M. Casa Vargas, Bruno Gabriel Nascimento Andrade et autres

In recent years, an increase in the prevalence hypermucoviscous carbapenem-resistant Klebsiella pneumoniae with sequence type 25 (ST25) was detected in hospitals of Tucuman (Northwest Argentina). In this work, the virulence and the innate immune response to two K. pneumoniae ST25 strains (LABACER …

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Draft genome sequences of two hypermucoviscous carbapenem-resistant ST25 Klebsiella pneumoniae strains causing respiratory and systemic infections

María Ángela Jure, Leonardo Albarracín, Juan M. Casa Vargas, Stefanía Dentice Maidana et autres

OBJECTIVES: The emergence and spread of hypermucoviscous KPC-2-producing Klebsiella pneumoniae strains belonging to the sequence type 25 (ST25) clone was reported recently in Northwest Argentina as a leading cause of nosocomial infections. The aim of this work was to perform whole-genome sequencing …

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