Markus Blaurock

BOA-Derived Volumetric CT Body Composition Provides Prognostic Information Beyond BMI in Surgically Treated Head and Neck Squamous Cell Carcinoma: A Retrospective Cohort Study

Charlotte Kamrath, Markus Blaurock, Nadine Hoepfner, Philipp Dittmann et autres

Background/Objectives: To evaluate whether automated three-dimensional volumetric body composition metrics from the Body and Organ Analysis (BOA) algorithm provide prognostic information beyond body mass index (BMI) for overall survival (OS) in surgically treated head and neck squamous cell carcinoma (HNSCC), and to …

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Roboterassistierte Chirurgie im Kopf-Hals-Bereich

Chia-Jung Busch, Tilman Huppertz, Markus Blaurock, Christopher Seifen et autres

Robot-assisted surgery has been established in the head and neck region as a promising minimally invasive method, particularly for oropharyngeal tumors. It enables precise tissue-preserving procedures with good oncological control and functional preservation. Modern systems offer multi- and single-port technologies, each providing …

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Malnutrition in gastrointestinal cancer manifests before systemic therapy and is associated with fatigue and reduced physical quality of life

Mats Lukas Wiese, Lena Schwarz, Sabrina von Rheinbaben, S. M. Schmidt et autres

BACKGROUND: There is a high malnutrition risk in patients with gastrointestinal tumors. Yet it is unknown when malnutrition manifests and how changes in nutritional status are related to quality of life and fatigue at different stages of oncologic therapy. PATIENTS AND METHODS: …

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Prähabilitation und „enhanced recovery after surgery“ bei onkologischen Operationen im Kopf-Hals-Bereich

Markus Blaurock, Chia-Jung Busch, Mats Lukas Wiese

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Movement Behaviors and the Role of Self‐Reported Symptoms and Well‐Being: A Dynamic Structural Equation Modeling Approach Among Head and Neck Cancer Patients

Sabina Ulbricht, Antje Ullrich, Christina Große-Thie, Daniel Fabian Strueder et autres

AIM: This study aimed to identify individual variability in day-to-day physical activity (PA) and sedentary behavior (SB) as well as effects of pain, fatigue, and well-being among patients with head and neck cancer (pwHNC) on both movement behaviors. METHODS: A total of …

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Bewegungstherapie in der Prähabilitation bei Kopf-Hals-Tumoren

Sabine Felser, Daniel Strüder, Markus Blaurock, Sabina Ulbricht

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Inflammation and limited adaptive immunity predict worse outcomes on immunotherapy in head and neck cancer

Lisa Paschold, Christoph Schultheiß, Paul Schmidt-Barbo, Konrad Friedrich Klinghammer et autres

Most patients with relapsed or metastatic head and neck squamous cell carcinoma (rmHNSCC) do not experience durable responses to PD-1 immune checkpoint inhibitors. PD-L1 tissue expression is the most commonly assessed response marker, but an insufficient predictor of treatment outcome. To identify …

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Individualized home training in head and neck cancer patients is safe and has positive short- and medium-term effects –results of a multicenter, single-arm intervention trial (OSHO #94)

Sabine Felser, Lars Arne Bonke, Anne S. Glass, Daniel Strüder et autres

Introduction Despite targeted exercise interventions alleviating functional deficits in head and neck cancer (HNC) patients, many patients are insufficiently physically active. A promising approach to reducing barriers could be individually adaptable home training. The “OSHO #94” study examined the short-term effectiveness, the …

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Structured Early Follow-Up in Head and Neck Squamous Cell Carcinomas: A Retrospective Cohort Study

Philipp Dittmann, Bernhard Lehnert, Friedrich Ihler, Chia‐Jung Busch et autres

Background/Objectives: The various head and neck squamous cell carcinoma (HNSCC) subtypes are among the most common cancers globally, with significant recurrence rates within the first two years post-treatment. Despite advancements in treatment, structured early follow-up remains crucial for timely diagnosis and effective …

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Prähabilitation und „enhanced recovery after surgery“ bei onkologischen Operationen im Kopf-Hals-Bereich

Markus Blaurock, Chia‐Jung Busch, Mats Lukas Wiese

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UV1 vaccination in pembrolizumab-treated patients with recurrent or metastatic head and neck cancer: A randomized multicenter phase 2 trial

Anna Paula Brandt, Konrad Friedrich Klinghammer, Christoph Schultheiß, Lisa Paschold et autres

BACKGROUND: Human telomerase reverse transcriptase is highly expressed in head and neck squamous cell carcinoma (HNSCC). The FOCUS study examines the role of the telomerase-directed vaccine UV1 in combination with pembrolizumab in patients with recurrent or metastatic (R/M) HNSCC. METHODS: HNSCC. A …

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Review of: "Computationally Optimized ctDNA Surveillance for Recurrence Detection in HPV-Positive Head and Neck Squamous Cell Carcinoma"

Markus Blaurock

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