Accès ouvert
2026
article
OpenAlex
Hangfan Liu, BJ Li, John Detre, Ze Wang
Arterial spin labeled (ASL) perfusion MRI is the only non-invasive and non-radioactive technique for measuring regional tissue perfusion. Perfusion signal in ASL MRI is derived from the difference between the spin labeled image and the spin untagged control image. Limited by the …
us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Ke Liu, Xia Xue, Haiming Qin, Jiaying Zhu et autres
Background: The gut microbiome has emerged as a critical modulator of cancer immunotherapy response. However, the mechanisms by which gut-associated metabolites influence checkpoint blockade efficacy in prostate cancer (PC) remain not fully explored. The study aimed to explore how gut metabolites regulate …
cn
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Natalia Vilor‐Tejedor, Samuel Danso, Ricardo D’Oliveira Albanus, Kimberley Billingsley et autres
Despite the global burden of dementia, research remains dominated by high-income, Western populations, limiting the generalizability and equity of findings. In this Perspective, we highlight the importance of diversity and inclusion in dementia research, not only in study participants but also in …
nl, es, gb, us, ie, au, sg
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Hangfan Liu, Bo Li, Yiran Li, Manuel Taso et autres
us
(code pays fourni par la source)
2025
conference-paper
OpenAlex
Hangfan Liu, Bo Li, Yiran Li, Manuel Taso et autres
Motivation: Signal-to-noise ratio (SNR) is relatively low in arterial spin labeling (ASL) MRI, particularly for high resolution, long post-labeling-delay, or long TE acquisitions. Goal(s): Increase ASL MRI SNR by leveraging data correlations among multi-channel data. Approach: Multi-coil Unified Sparsity regularization using Inter-slice …
Accès ouvert
2025
article
OpenAlex
Sokratis Charisis, Tanweer Rashid, Christina S. Dintica, Mitzi M. Gonzales et autres
INTRODUCTION: We aimed to examine the global impact of brain small vessel disease (SVD) on cognitive performance. METHODS: In 892 participants from the Multi-Ethnic Study of Atherosclerosis (MESA), we derived perivascular spaces (PVS), white matter hyperintensities (WMH), microbleeds (MB), and white matter …
us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Sokratis Charisis, Tanweer Rashid, Christina S. Dintica, Mitzi M. Gonzales et autres
Abstract Background The location of proposed brain MRI markers of small vessel disease (SVD) might reflect their pathogenesis and may translate into differential associations with cognition. We derived regional MRI markers of SVD and studied: (i) associations with cognitive performance, (ii) patterns …
us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Sokratis Charisis, Tanweer Rashid, Christina S. Dintica, Mitzi M. Gonzales et autres
Abstract Background The location of proposed brain MRI markers of small vessel disease (SVD) might reflect their pathogenesis and may translate into differential associations with cognition. We derived regional MRI markers of SVD and studied: (i) associations with cognitive performance, (ii) patterns …
us
(code pays fourni par la source)
2024
conference-paper
OpenAlex
Hangfan Liu, Bo Li, Yiran Li, John A. Detre et autres
Motivation: Address the challenge of low SNR in arterial spin labeling (ASL) MRI that hinders its clinical and research potential. Goal(s): Develop an advanced ASL denoising algorithm that enhances image quality and overcomes limitations in ASL due to low SNR. Approach: Propose …
2024
conference-paper
OpenAlex
Bo Li, Hangfan Liu, Yiran Li, Manuel Taso et autres
Motivation: To assess the blood-CSF barrier on a Siemens platform using a multi-TE 3D RARE stack-of-spirals ASL sequence. Goal(s): To obtain high-quality fitted blood-to-csf time images. Approach: A 3D RARE pCASL sequence with multiple-TE acquisitions was used to collect ASL images. To …
Accès ouvert
2024
conference-paper
OpenAlex
Hangfan Liu, Bo Li, Yiran Li, Manuel Taso et autres
Arterial spin labeling (ASL) magnetic resonance imaging (MRI) is the only non-invasive technique for measuring regional cerebral blood flow (CBF) and related neurovascular properties. ASL data can be acquired at multiple echo times (TE) to estimate transit time from blood to tissue …
us
(code pays fourni par la source)
Accès ouvert
2024
conference-paper
OpenAlex
Hangfan Liu, Bo Li, Yiran Li, John A. Detre et autres
Arterial spin-labeled (ASL) perfusion MRI remains the only non-invasive, radiation-free method for quantifying regional tissue perfusion. ASL MRI computes perfusion signals from the difference of the spin-labeled images and spin-untagged control images. Limited by the T1 decay of the labeled arterial blood, …
us
(code pays fourni par la source)