Konstantin Christoph Koban

International survey on the use of tranexamic acid in plastic surgery—Current practices and perspectives

Irene Mesas Aranda, Benedikt Fuchs, Felix Hubertus Vollbach, Nikolaus Thierfelder et autres

Background: Tranexamic acid (TXA) has gained increasing popularity in plastic and reconstructive surgery for minimizing perioperative bleeding and improving postoperative outcomes. However, standardized guidelines on its use remain lacking. Methods: An anonymous international survey was distributed to over 400 plastic surgeons worldwide …

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Quantifying Morphological Change in Stage III Lipedema: A 3D Imaging Study of Population Trends and Individual Treatment Courses

Niels A. Sanktjohanser, Nikolaus Thierfelder, Benjamin H. Beck, Sinan Mert et autres

Background/Objectives: Lipedema is a chronic disorder characterized by disproportionate fat accumulation in the extremities, causing pain, bruising, and reduced mobility. When conservative therapy fails, liposuction is considered an effective treatment option. Prior studies often relied on subjective or non-standardized measures, limiting precision. …

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Augmenting Patient Education in Hand Surgery—Evaluation of ChatGPT as an Informational Tool in Carpal Tunnel Syndrome

Benedikt Fuchs, Nikolaus Thierfelder, Irene Mesas Aranda, Verena Alt et autres

Background and Objectives: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by chronic compression of the median nerve within the carpal tunnel. Patient education is a cornerstone of informed consent and postoperative outcomes, yet time constraints often limit traditional …

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Open Access: In Between the Bright and the Dark Side

Paolo Alberton, Paul Severin Wiggenhauser, Nicholas Möllhoff, Konstantin Christoph Koban et autres

Zusammenfassung Die Open-Access-Bewegung nahm bereits in den 90er Jahren ihren Anfang, doch erst in den vergangenen Jahren hat sie sich als fester Bestandteil der wissenschaftlichen Praxis etabliert und ein sichtbares Engagement der Fachgemeinschaft erfahren. Während Open Access grundsätzlich darauf abzielt, den Zugang …

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Plastisch-chirurgische Versorgung von Leistendefekten bei infizierten Gefäßprothesen: Managementstrategien und praxisorientierter Algorithmus

Irene Mesas Aranda, Konstantin Christoph Koban, Sinan Mert, Benedikt Fuchs et autres

Infections involving vascular prostheses in the groin region are a major surgical challenge, associated with substantial morbidity and mortality rates. The complex anatomical structures and high density of bacterial colonisation considerably complicate their surgical management. Consequently, reconstructive therapy demands individualised and interdisciplinary …

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Microsurgical Lymphatic Vessel Transplantation for Chronic Lymphedema: Long-Term Evaluation of Volume Reduction and Lymphatic Transport Kinetics

Wolfram Demmer, Louisa Antonie Hock, Konstantin Christoph Koban, Paul Severin Wiggenhauser et autres

This study investigates long-term volume reduction after microsurgical autologous lymphatic vessel transplantation (LVT) in patients with chronic lymphoedema. Lymphoedema is caused by inadequate lymphatic drainage and leads to swelling, pain, and a reduced quality of life. Conservative treatments often show only limited …

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Aspirin Inhibits the In Vitro Adipogenic Differentiation of Human Adipose Tissue-Derived Stem Cells in a Dose-Dependent Manner

Sarah Funke, Paul Severin Wiggenhauser, Anna Grundmeier, Benedikt Fuchs et autres

Aspirin (ASA) is one of the most used medications worldwide and has shown various effects on cellular processes, including stem cell differentiation. However, the effect of ASA on adipogenesis of adipose tissue-derived stem cells (ASCs) remains largely unknown. Considering the potential application …

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3D Oberflächenbildgebung: Innovationen und Stellenwert in der Plastischen Chirurgie

Konstantin Christoph Koban

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To Shrink or Not to Shrink? An Objective Assessment of Free Gracilis Muscle Volume Change in Lower-Extremity Defect Reconstruction

Konstantin Christoph Koban, Constanze Kuhlmann, Nikolaus Wachtel, Maximilian Hirschmann et autres

Background: The use of free gracilis muscle flaps in reconstructive surgery of the lower leg is common practice to cover defects. However, there is still a lack of understanding of the morphometric changes that occur in the transferred muscle and area of …

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Quality of Life in Lymphedema Patients Treated by Microsurgical Lymphatic Vessel Transplantation—A Long-Term Follow-Up

Louisa Antonie Hock, Tim Nürnberger, Konstantin Christoph Koban, Paul Severin Wiggenhauser et autres

Introduction: Lymphedema is a chronic condition characterized by the accumulation of lymph fluid in the upper or lower extremities, leading to swelling, discomfort, and disability in everyday life. While various treatment modalities exist, microsurgical lymphatic vessel transplantation (LVT) has emerged as a …

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Aspirin Stimulates the Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells In Vitro

Sarah Funke, Paul Severin Wiggenhauser, Anna Grundmeier, Sara Taha et autres

This study investigates the impact of acetylsalicylic acid (ASA), also known as aspirin, on adipose tissue-derived stem cells (ASCs), aiming to elucidate its dose-dependent effects on morphology, viability, proliferation, and osteogenic differentiation. Isolated and characterized human ASCs were exposed to 0 µM, …

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Erfolgreiche Nervenrekonstruktion: ein Fallbericht bei Nervus axillaris – Verletzung einer Profisportlerin

Elisabeth Maria Haas-Lützenberger, Mortimer M. Hladik, Konstantin Christoph Koban, Riccardo Enzo Giunta

Unter den Sportarten mit hoher Geschwindigkeit zeigen sich im alpinen Abfahrtslauf vermehrt Hochrasanztraumata. Am Fallbericht einer jungen professionellen Skirennläuferin, die im Rahmen eines Weltcuprennens eine Schulterluxation mit Abriss des Nervus axillaris erlitt, wird die Bedeutung frühzeitiger Diagnostik, Vorstellung in einem Zentrum für …