Accès ouvert
2026
article
OpenAlex
Benedikt Fuchs, Vanessa Lucksch, Constanze Kuhlmann, Irene Mesas Aranda et autres
Background: Traumatic auricular amputation represents a rare but complex reconstructive challenge, and numerous surgical techniques have been developed over the past century to optimize functional and aesthetic outcomes. This historical review examines current auricular reattachment and replantation strategies by comparing established surgical …
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Accès ouvert
2025
article
OpenAlex
Benedikt Fuchs, Sinan Mert, Constanze Kuhlmann, Nikolaus Thierfelder et autres
BACKGROUND: Traumatic auricular amputations present a unique surgical challenge, particularly in cases where microsurgical anastomosis is not feasible due to vessel damage or absence. Traditional reconstruction techniques often yield suboptimal aesthetic or functional results. The pocket technique, as described by Sexton and …
de
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Accès ouvert
2025
article
OpenAlex
Niels A. Sanktjohanser, Nikolaus Thierfelder, Benjamin H. Beck, Sinan Mert et autres
Background/Objectives: Lipedema is a chronic disorder characterized by disproportionate fat accumulation in the extremities, causing pain, bruising, and reduced mobility. When conservative therapy fails, liposuction is considered an effective treatment option. Prior studies often relied on subjective or non-standardized measures, limiting precision. …
de
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2025
article
OpenAlex
Benedikt Fuchs, Tim Nürnberger, Sinan Mert, Petra Zimmermann et autres
Lymphoedema is a chronic, progressive condition that may occur as a primary disorder or secondarily following lymphatic damage, such as after lymphadenectomy or radiotherapy. Conservative therapies often provide only limited relief, so that surgical approaches like vascularised omental lymph node transfer (VOLT) …
ch, de
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Accès ouvert
2025
article
OpenAlex
Paolo Alberton, Paul Severin Wiggenhauser, Nicholas Möllhoff, Konstantin Christoph Koban et autres
Zusammenfassung Die Open-Access-Bewegung nahm bereits in den 90er Jahren ihren Anfang, doch erst in den vergangenen Jahren hat sie sich als fester Bestandteil der wissenschaftlichen Praxis etabliert und ein sichtbares Engagement der Fachgemeinschaft erfahren. Während Open Access grundsätzlich darauf abzielt, den Zugang …
de
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Accès ouvert
2025
article
OpenAlex
Wolfram Demmer, Louisa Antonie Hock, Konstantin Christoph Koban, Paul Severin Wiggenhauser et autres
This study investigates long-term volume reduction after microsurgical autologous lymphatic vessel transplantation (LVT) in patients with chronic lymphoedema. Lymphoedema is caused by inadequate lymphatic drainage and leads to swelling, pain, and a reduced quality of life. Conservative treatments often show only limited …
de
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Accès ouvert
2025
article
OpenAlex
Benedikt Fuchs, Sinan Mert, Daniel Hofmann, Constanze Kuhlmann et autres
Chronic wounds represent an unresolved medical challenge with significant impact for patients’ quality of life and global healthcare. Diverse in origin, ischemic-hypoxic and inflammatory conditions play central roles as pathological features that impede proper tissue regeneration. In this study, we propose an …
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Accès ouvert
2025
article
OpenAlex
Sarah Funke, Paul Severin Wiggenhauser, Anna Grundmeier, Benedikt Fuchs et autres
Aspirin (ASA) is one of the most used medications worldwide and has shown various effects on cellular processes, including stem cell differentiation. However, the effect of ASA on adipogenesis of adipose tissue-derived stem cells (ASCs) remains largely unknown. Considering the potential application …
de
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Accès ouvert
2024
article
OpenAlex
Benedikt Fuchs, Sinan Mert, Constanze Kuhlmann, Alexandra Birt et autres
Cyanobacteria, commonly known as blue-green algae, are prevalent in freshwater systems and have gained interest for their potential in medical applications, particularly in skin regeneration. Among these, Synechococcus sp. strain PCC 7002 stands out because of its rapid proliferation and capacity to …
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Accès ouvert
2024
article
OpenAlex
Louisa Antonie Hock, Tim Nürnberger, Konstantin Christoph Koban, Paul Severin Wiggenhauser et autres
Introduction: Lymphedema is a chronic condition characterized by the accumulation of lymph fluid in the upper or lower extremities, leading to swelling, discomfort, and disability in everyday life. While various treatment modalities exist, microsurgical lymphatic vessel transplantation (LVT) has emerged as a …
de
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Accès ouvert
2024
article
OpenAlex
Sarah Funke, Paul Severin Wiggenhauser, Anna Grundmeier, Sara Taha et autres
This study investigates the impact of acetylsalicylic acid (ASA), also known as aspirin, on adipose tissue-derived stem cells (ASCs), aiming to elucidate its dose-dependent effects on morphology, viability, proliferation, and osteogenic differentiation. Isolated and characterized human ASCs were exposed to 0 µM, …
de
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2024
review
OpenAlex
Wolfram Demmer, Jannik Schinacher, Paul Severin Wiggenhauser, Riccardo E. Giunta
Significance:Cartilage regeneration remains a significant challenge in the field of regenerative medicine. Acellular matrix (AM)-based cartilage tissue regeneration offers an innovative approach to repairing cartilage defects by providing a scaffold for new tissue growth. Its significance lies in its potential to restore …
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