Laura Pabón

New genomic resources and the historical demography of the Tourmaline Sunangel (Trochilidae, Heliangelus exortis ) in the Colombian Andes

Carlos Daniel Cadena, Laura Pabón, Andrés Felipe Díaz-Salazar, Maria Elisa Mendiwelso et autres

Understanding the demographic history of tropical montane species offers insights into how climate-driven habitat dynamics shape genetic diversity and population structure. The Tourmaline Sunangel (Heliangelus exortis), a hummingbird endemic to the Northern Andes of Colombia and Ecuador, inhabits high-elevation ecosystems that were …

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A reference genome for the Andean cavefish Trichomycterus rosablanca (Siluriformes, Trichomycteridae): Building genomic resources to study evolution in cave environments

Carlos Daniel Cadena, Laura Pabón, Carlos DoNascimiento, Linelle Ann L. Abueg et autres

Animals living in caves are of broad relevance to evolutionary biologists interested in understanding the mechanisms underpinning convergent evolution. In the Eastern Andes of Colombia, populations from at least two distinct clades of Trichomycterus catfishes (Siluriformes) independently colonized cave environments and converged …

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A reference genome for the Andean cavefish Trichomycterus rosablanca (Siluriformes, Trichomycteridae): building genomic resources to study evolution in cave environments

Carlos Daniel Cadena, Laura Pabón, Carlos DoNascimiento, Linelle Ann L. Abueg et autres

Abstract Animals living in caves are of broad relevance to evolutionary biologists interested in understanding the mechanisms underpinning convergent evolution. In the Eastern Andes of Colombia, populations from at least two distinct clades of Trichomycterus catfishes (Siluriformes) independently colonized cave environments and …

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Identification of Babesia bovis MSA-1 functionally constraint regions capable of binding to bovine erythrocytes

Laura Cuy-Chaparro, Laura Alejandra Ricaurte-Contreras, Michel David Bohórquez, Gabriela Arévalo‐Pinzón et autres

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SM-COLSARSPROT: Highly Immunogenic Supramutational Synthetic Peptides Covering the World’s Population

Manuel A. Patarroyo, Laura Pabón, Martha Patricia Alba, Adriana Bermúdez et autres

Fifty ~20–amino acid (aa)–long peptides were selected from functionally relevant SARS-CoV-2 S, M, and E proteins for trial B-21 and another 53 common ones, plus some new ones derived from the virus’ main genetic variants for complementary trial C-21. Peptide selection was …

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The First Chemically-Synthesised, Highly Immunogenic Anti-SARS-CoV-2 Peptides in DNA Genotyped Aotus Monkeys for Human Use

Manuel E. Patarroyo, Manuel A. Patarroyo, Martha Patricia Alba, Laura Pabón et autres

Thirty-five peptides selected from functionally-relevant SARS-CoV-2 spike (S), membrane (M), and envelope (E) proteins were suitably modified for immunising MHC class II (MHCII) DNA-genotyped Aotus monkeys and matched with HLA-DRβ1* molecules for use in humans. This was aimed at producing the first …

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Babesia Bovis Ligand-Receptor Interaction: AMA-1 Contains Small Regions Governing Bovine Erythrocyte Binding

Laura Cuy-Chaparro, Michel David Bohórquez, Gabriela Arévalo‐Pinzón, Jeimmy Johana Castañeda-Ramírez et autres

Apical membrane antigen 1 is a microneme protein which plays an indispensable role during Apicomplexa parasite invasion. The detailed mechanism of AMA-1 molecular interaction with its receptor on bovine erythrocytes has not been completely defined in Babesia bovis. This study was focused …

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Malaria: Paving the way to developing peptide-based vaccines against invasion in infectious diseases

César Reyes, Jessica Molina-Franky, Jorge Aza-Conde, Carlos Fernando Suárez et autres

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Caracterización de la población ciclista de la ciudad de Popayán

Claudia Liceth Fajardo Hoyos, Laura Pabón, Daniel Antonio León Blanco, Andrea Zemanate Chavez

Efecto Inhibidor de la Miel De Bórax sobre el crecimiento de Candida Albicans, aislada de pacientes con lesiones de Estomatitis Subprotesica

Laura Pabón, María L. Lugo, R Lorena Bustillos, Anajulia González Betancourt et autres

En la cavidad bucal se presentan diversas patologias, una de las mas frecuentes es la estomatitis subprotesica (ESP) de etiologia multifactorial que afecta con alta prevalencia a pacientes portadores de protesis totales y frecuentemente esta asociada a Candida albicans. La conducta terapeutica …

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Structural analysis of owl monkey MHC-DR shows that fully-protective malaria vaccine components can be readily used in humans

Carlos Fernando Suárez, Laura Pabón, Ana María Bermejo Barrera, Jorge Aza-Conde et autres

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Far from the Madding Crowd: the Molecular Basis for Immunological Escape of Plasmodium falciparum

Manuel E. Patarroyo, Jorge Aza-Conde, Armando Moreno-Vranich, Laura Pabón et autres

parasites display their most relevant survival structures (proteins) involved in host cell invasion far away from the immune system's susceptible regions, displaying tremendous genetic variability, to attract the immune response and escape immune pressure. The 3D structure localisation of the conserved amino …

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