Claudie Verwaerde

Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria

Dominique Raze, Claudie Verwaerde, Gaspard Deloison, Elisabeth Werkmeister et autres

The heparin-binding hemagglutinin (HBHA) is an important virulence factor of Mycobacterium tuberculosis. It is a surface-displayed protein that serves as an adhesin for non-phagocytic cells and is involved in extra-pulmonary dissemination of the tubercle bacillus. It is also an important latency antigen …

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HBHA vaccination may require both Th1 and Th17 immune responses to protect mice against tuberculosis

Claudie Verwaerde, Anne‐Sophie Debrie, Christophe Youta Dombu, Damien Legrand et autres

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Interleukin-7 Regulates Adipose Tissue Mass and Insulin Sensitivity in High-Fat Diet-Fed Mice through Lymphocyte-Dependent and Independent Mechanisms

Stéphanie Lucas, Solenne Taront, Chr̀istophe Magnan, Laurence Fauconnier et autres

Although interleukin (IL)-7 is mostly known as a key regulator of lymphocyte homeostasis, we recently demonstrated that it also contributes to body weight regulation through a hypothalamic control. Previous studies have shown that IL-7 is produced by the human obese white adipose …

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and Steady-State Number in Obese Mice Impairment of Dendritic Cell Functionality

Pasquine Saule, Isabelle Wolowczuk, Tan‐Sothéa Ouk, Anne Delanoye et autres

Pasquine Saule and Isabelle WolowczukTan-Sothea Ouk, Anne Delanoye, Claudie Verwaerde, Laurence Macia, Myriam Delacre, Georges Abboud,http://www.jimmunol.org/content/177/9/5997J Immunol€2006; 177:5997-6006; ;Referenceshttp://www.jimmunol.org/content/177/9/5997.full#ref-list-1This article cites 54 articles, 15 of which you can access for free at: Subscriptionshttp://jimmunol.org/subscriptionsInformation about subscribing to The Journal of Immunology is online …

Induction of Therapeutic Antibodies by Vaccination against External Loops of Tumor-Associated Viral Latent Membrane Protein

C. Delbende, Claudie Verwaerde, Alexandra Mougel, Denis Tranchand Bunel

Some human herpesviruses (HHV) are etiological contributors to a wide range of malignant diseases. These HHV express latent membrane proteins (LMPs), which are type III membrane proteins consistently exposed at the cell surface in these malignancies. These LMPs have relatively large cytoplasmic …

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Subcutaneous graft of D1 mouse mesenchymal stem cells leads to the formation of a bone-like structure

Olivier Juffroy, Danièle Noël, Anne Delanoye, Odile Viltart et autres

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Allergens of Schistosoma mansoni

Raymond J. Pierce, Claudie Verwaerde, Martine Damonneville, Thérèse LePresle et autres

The reaction of adult worm products of Schistosoma mansoni with IgE antibodies in infected human and Fischer rat sera has been studied using the Prausnitz-Küstner test and the radioallergosorbent test. Incubation of worms in water released most of the soluble material reacting …

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Induction of a Protective Immune IgE Response in Rats by Injection of Defined Antigens of Schistosomulum-Released Products: Immunochemical Properties of the Target Antigens

Martine Damonneville, Claude Auriault, T. Thorel, Claudie Verwaerde et autres

Brown Norway rats were injected without adjuvant with the soluble products liberated in a 16-hour culture by schistosomula (schistosomula-released products, SRP-A). A strong cytotoxic and protective IgE response was elicited, mainly directed against 22- and 26-kilodalton (kDa) SRP-A molecules. In the present …

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Allergens of Schistosoma mansoni

Martine Damonneville, Raymond J. Pierce, Claudie Verwaerde, Andr eacute Capron

The interaction of Schistosoma mansoni crude soluble egg antigen (SEA) with IgE antibodies in sera from S. mansoni-infected mice, rats and humans has been studied by the radioallergosorbent test (RAST) and the Prausnitz-Küstner (PK) technique. IgE antibodies recognizing egg antigens were present …

Erwin Neter (1909–1983)

Malcolm Richardson, David W. Warnock, P. Miossec, P Youinou et autres

Is the Adipose Tissue the Key Road to Inflammation?

Stéphanie Lucas, Claudie Verwaerde, Isabelle Wolowczuk

It is now broadly accepted that white adipose tissue disorders, such as obesity, are associated with a chronic low-grade inflammation predisposing to the development of insulin-resistance, type 2 diabetes and cardiovascular complications. In obesity, accumulation of visceral adipose tissue, rather than subcutaneous …

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Feeding Our Immune System: Impact on Metabolism

Isabelle Wolowczuk, Claudie Verwaerde, Odile Viltart, Anne Delanoye et autres

Endogenous intestinal microflora and environmental factors, such as diet, play a central role in immune homeostasis and reactivity. In addition, microflora and diet both influence body weight and insulin-resistance, notably through an action on adipose cells. Moreover, it is known since a …

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