Anne Delanoye

Interleukin-7 Regulates Adipose Tissue Mass and Insulin Sensitivity in High-Fat Diet-Fed Mice through Lymphocyte-Dependent and Independent Mechanisms

Stéphanie Lucas, Solenne Taront, Chr̀istophe Magnan, Laurence Fauconnier et autres

Although interleukin (IL)-7 is mostly known as a key regulator of lymphocyte homeostasis, we recently demonstrated that it also contributes to body weight regulation through a hypothalamic control. Previous studies have shown that IL-7 is produced by the human obese white adipose …

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and Steady-State Number in Obese Mice Impairment of Dendritic Cell Functionality

Pasquine Saule, Isabelle Wolowczuk, Tan‐Sothéa Ouk, Anne Delanoye et autres

Pasquine Saule and Isabelle WolowczukTan-Sothea Ouk, Anne Delanoye, Claudie Verwaerde, Laurence Macia, Myriam Delacre, Georges Abboud,http://www.jimmunol.org/content/177/9/5997J Immunol€2006; 177:5997-6006; ;Referenceshttp://www.jimmunol.org/content/177/9/5997.full#ref-list-1This article cites 54 articles, 15 of which you can access for free at: Subscriptionshttp://jimmunol.org/subscriptionsInformation about subscribing to The Journal of Immunology is online …

Subcutaneous graft of D1 mouse mesenchymal stem cells leads to the formation of a bone-like structure

Olivier Juffroy, Danièle Noël, Anne Delanoye, Odile Viltart et autres

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Feeding Our Immune System: Impact on Metabolism

Isabelle Wolowczuk, Claudie Verwaerde, Odile Viltart, Anne Delanoye et autres

Endogenous intestinal microflora and environmental factors, such as diet, play a central role in immune homeostasis and reactivity. In addition, microflora and diet both influence body weight and insulin-resistance, notably through an action on adipose cells. Moreover, it is known since a …

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Presence of HIV-1 Nef specific CD4 T cell response is associated with non-progression in HIV-1 infection

Véronique Pancré, Nadira Delhem, Yazdan Yazdanpanah, Anne Delanoye et autres

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Impairment of Dendritic Cell Functionality and Steady-State Number in Obese Mice

Laurence Macia, Myriam Delacre, Georges Abboud, Tan‐Sothéa Ouk et autres

There is a finely tuned interplay between immune and neuroendocrine systems. Metabolic disturbances like obesity will have serious consequences on immunity both at the cellular and at the cytokine expression levels. Our in vivo results confirm the immune deficiency of ob/ob mice, …

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Influence of High‐Fat Feeding on Both Naive and Antigen‐Experienced T‐Cell Immune Response in DO10.11 Mice

Claudie Verwaerde, Anne Delanoye, Laurence Macia, Anne Tailleux et autres

Obesity is becoming one of the most serious public health problems in industrialized societies, due to the profound changes in lifestyle, and notably in nutrition. Beside diabetes, cardiovascular diseases or hypertension, increased susceptibility to infection is one of the pathological consequences of …

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Genes involved in obesity: Adipocytes, brain and microflora

Laurence Macia, Odile Viltart, Claudie Verwaerde, Myriam Delacre et autres

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Tetracycline-Inducible Viral Interleukin-10 Intraocular Gene Transfer, Using Adeno-Associated Virus in Experimental Autoimmune Uveoretinitis

Justine R. Smith, Claudie Verwaerde, Fabienne Rolling, Marie‐Christine Naud et autres

Members of the adeno-associated virus (AAV) family are good candidates for the treatment of ocular diseases because of their relative lack of pathogenicity. We studied the effect of intraocular injection of AAV2-viral IL-10 (vIL-10) on retinal S-antigen-induced experimental autoimmune uveoretinitis (EAU) in …

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Ocular transfer of retinal glial cells transduced ex vivo with adenovirus expressing viral IL-10 or CTLA4-Ig inhibits experimental autoimmune uveoretinitis

Claudie Verwaerde, M-C Naud, Anne Delanoye, Matthew J. A. Wood et autres

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Novel promiscuous HLA-DQ HIV Nef peptide that induces IFN-γ-producing memory CD4+T cells

Véronique Pancré, Bertrand Georges, Gerhild Angyalosi, Florence Castelli et autres

We describe the highly conserved sequence 56-68 of the HIV Nef protein as the first promiscuous HLA-DQ HIV-derived peptide. The Nef peptide exhibits an albeit rare capacity to bind 6 different HLA-DQ molecules whereas no binding is observed with the 10 HLA-DR …

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HLA Class II Polymorphism Influences Onset and Severity of Pathology inSchistosoma mansoni-Infected Transgenic Mice

Gerhild Angyalosi, Raphaële Neveu, Isabelle Wolowczuk, Anne Delanoye et autres

Genetic factors that might influence susceptibility or resistance in naive individuals and early-stage pathology in schistosomiasis are difficult to study in clinical trials, since in areas where the disease is endemic the first contact with the parasite occurs most often at very …

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