Abdullah Al Shamsh Prottay

Anti-nociceptive property of thymol: animal study with molecular docking and MD simulation studies

Rokibul Islam Chowdhury, Mehedi Hasan Bappi, S U Ahammed, Md Sabbir Hossain et autres

bd, us, sa, br (code pays fourni par la source)

Thymol as a Potential Natural Antiemetic: Insights From In Vivo and In Silico Studies

Showkoth Akbor, Mehedi Hasan Bappi, Abdullah Al Shamsh Prottay, Farjanamul Haque et autres

ABSTRACT Nausea and vomiting are common and distressing responses to toxins, chemotherapy, and gastrointestinal disturbances. Although antiemetic medications are available, their adverse effects make safer substitutes necessary. In our study, Thymol (THY), a phenolic monoterpene from essential oils, was evaluated for its …

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Memory-Enhancing Effects of Daidzin, Possibly Through Dopaminergic and AChEergic Dependent Pathways

Muhammad Torequl Islam, Abdullah Al Shamsh Prottay, Md. Shimul Bhuia, Md. Showkoth Akbor et autres

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Anxiogenic-like effects of coumarin, possibly through the GABAkine interaction pathway: Animal studies with in silico approaches

Abdullah Al Shamsh Prottay, Emamuzzaman, Tawfik Rakaiyat Ripu, Md Shahid Sarwar et autres

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Anxiolytic-like effect of daidzin possibly through GABAA receptor α2 and α3 subunits interaction pathway: In vivo and in silico studies

Muhammad Torequl Islam, Abdullah Al Shamsh Prottay, Md. Showkoth Akbor, Md. Shimul Bhuia et autres

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Quercetin increases the antidepressant‐like effects of sclareol and antagonizes diazepam in thiopental sodium‐induced sleeping mice: A possible GABAergic transmission intervention

Mehedi Hasan Bappi, Md. Nayem Mia, Siddique Akber Ansari, Irfan Aamer Ansari et autres

Abstract Quercetin is the most common polyphenolic flavonoid present in fruits and vegetables demonstrating versatile health‐promoting effects. This study aimed to examine the effects of quercetin (QR) and sclareol (SCL) on the thiopental sodium (TS)‐induced sleeping and forced swimming test (FST) mouse …

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Sclareol exerts an anti-inflammatory effect, possibly through COXs inhibition pathway: In vivo and in silico studies

Abdullah Al Shamsh Prottay, Mehedi Hasan Bappi, Md. Showkoth Akbor, Afia Ibnath Asha et autres

Chronic and severe inflammation results in many diseases and disorders in humans. Currently, available conventional anti-inflammatory drugs have numerous mild-to-severe side effects. Thus, there is a need for safe, effective, affordable, and alternative anti-inflammatory drugs. This study aimed to evaluate the anti-inflammatory …

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Sclareol exerts synergistic antidepressant effects with quercetin and caffeine, possibly suppressing GABAergic transmission in chicks

Hossam Mohammed Kamli, Ahmad A. Shaikh, Mehedi Hasan Bappi, António Raposo et autres

This study evaluated the effects of sclareol (SCL) with or without caffeine (CAF) and quercetin (QUR) using in-vivo and in-silico studies. For this, 5-day-old chicks weighing between 45 and 48 g were randomly divided into five groups and treated accordingly. The chicks …

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Antiemetic effects of sclareol, possibly through 5-HT3 and D2 receptor interaction pathways: In-vivo and in-silico studies

Mehedi Hasan Bappi, Abdullah Al Shamsh Prottay, Khattab Al-Khafaji, Md. Showkoth Akbor et autres

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The efficacy of natural bioactive compounds against prostate cancer: Molecular targets and synergistic activities

Md. Abdur Rashid Mia, Dipta Chandra Dey, Musfiqur Rahman Sakib, Md. Yeaman Biswas et autres

Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number of PCa patients continues to rise despite the availability of effective treatments in recent decades. The current therapy with chemotherapeutic drugs has been largely ineffective due to multidrug …

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Anxiolytic-like effect of succinic acid: A possible GABAergic intervention

Md. Nayem Mia, Shanita Zaman Smrity, Mehedi Hasan Bappi, Hossam Mohammed Kamli et autres

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Quercetin Antagonizes the Sedative Effects of Linalool, Possibly through the GABAergic Interaction Pathway

Mehedi Hasan Bappi, Abdullah Al Shamsh Prottay, Hossam Mohammed Kamli, Fatema Akter Sonia et autres

Sedatives promote calmness or sleepiness during surgery or severely stressful events. In addition, depression is a mental health issue that negatively affects emotional well-being. A group of drugs called anti-depressants is used to treat major depressive illnesses. The aim of the present …

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