Mustafa Vurma

Lipid-fortified diets protect against intestinal inflammation and dysmotility in neonatal mice

Chhinder P. Sodhi, Cody Tragesser, Daniel Scheese, Johannes W. Duess et autres

Abstract Newborn infants are at increased risk of gastrointestinal dysfunction, inflammation, and feeding intolerance because their digestive and immune systems are not fully developed. BioLipids-fortified diets enriched with a blend of medium-chain triglycerides (MCTs), mono- and diglycerides (MDGs), and milk phospholipids (MPLs) …

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Effects of new lipid ingredients during pregnancy and lactation on rat offspring brain gene expression

Valentina Origüela, Antonio Gázquez, María José López-Andreo, Pilar Bueno-Vargas et autres

Maternal dietary fat intake during pregnancy and lactation may influence the bioavailability of essential lipophilic nutrients, such as docosahexaenoic acid (DHA), that are important for both the mother and her child's development. This study aimed to evaluate the effects of different maternal …

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P07-034-23 A Novel Mono- and Diglyceride Emulsion Improves DHA Absorption

Brian J. Leyshon, Mustafa Vurma, Matthew J. Kuchan, Patrick Tso et autres

The administration of a pre-digested fat-enriched formula prevents necrotising enterocolitis-induced lung injury in mice

Chhinder P. Sodhi, Andres Salazar, Mark L. Kovler, William B. Fulton et autres

Necrotising enterocolitis (NEC) is a devastating gastrointestinal disease of prematurity that typically develops after the administration of infant formula, suggesting a link between nutritional components and disease development. One of the most significant complications that develops in patients with NEC is severe …

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Early Enteral Administration of a Complex Lipid Emulsion Supplement Prevents Postnatal Deficits in Docosahexaenoic and Arachidonic Acids and Increases Tissue Accretion of Lipophilic Nutrients in Preterm Piglets

Olajumoke Akinsulire, George Perides, Lorenzo Anez‐Bustillos, Joanne E. Cluette‐Brown et autres

BACKGROUND: Preterm delivery and current nutrition strategies result in deficiencies of critical long-chain fatty acids (FAs) and lipophilic nutrients, increasing the risk of preterm morbidities. We sought to determine the efficacy of preventing postnatal deficits in FAs and lipophilic nutrients using an …

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Fat composition in infant formula contributes to the severity of necrotising enterocolitis

Chhinder P. Sodhi, William B. Fulton, Misty Good, Mustafa Vurma et autres

Necrotising enterocolitis (NEC) is a devastating disease that typically affects formula-fed premature infants, suggesting that dietary components may influence disease pathogenesis. TAG are the major fat components of infant formula, and their digestion requires pancreatic lipases, which may be naturally deficient in …

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Effect of mono- and diglycerides on the digestion and absorption of lutein in lymph fistula rats

Patrick Tso, Mustafa Vurma, Chih‐Wei Ko, Dana Lee et autres

Breast milk lutein is better absorbed by infants than lutein delivered in infant formula. Therefore, we wanted to better understand the possible absorption differences of lutein in breast milk vs. that in infant formula by determining its bioavailability after gastric administration and …

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Mono- and diglycerides improve lutein absorption in healthy adults: a randomised, double-blind, cross-over, single-dose study

Barbara Marriage, Jennifer Williams, Yong Choe, Kevin C. Maki et autres

With the association between increased carotenoid intake and lower risk of chronic diseases, the absorption of lutein from the diet becomes an important factor in its delivery and physiological action. The primary objective of this study was to gain an understanding of …

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Evaluation of Different Delivery Vehicles on the Digestion and Absorption of Lutein using a Lymph Fistula Rat Model

Patrick Tso, Mustafa Vurma, Dana Lee, Stephen J. DeMichele

Lutein delivered through breast milk is better absorbed by infants than lutein delivered in infant formula. We wish to better understand the possible absorption differences of lutein in breast milk versus infant formula by determining its bioavailability after gastric administration and to …

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In vivo Assessment of Lutein Absorption in Infant Formula using Mono‐diglycerides (MDG) Based Emulsification Technology

Mustafa Vurma, Stephen J. DeMichele, Dana Lee, Patrick Tso

Previously we showed using the lymph fistula rat model that specific mixtures of MDG improved lymphatic lutein absorption by solubilizing lutein and facilitating gastrointestinal micelle formation compared to lutein suspended in triglyceride oils. The primary objective of this study was to determine …

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Carrageenan analysis. Part 1: Characterisation of the carrageenan test material and stability in swine-adapted infant formula

William R. Blakemore, Steven R. Davis, Maggie M. Hroncich, Mustafa Vurma

A method was developed and validated in support of a 28-day feeding study of swine-adapted infant formula stabilised with carrageenan administered to neonatal piglets. Carrageenan concentrations in the test formulations were 0, 300, 1000 and 2250 mg kg(-1) formula. Extraction of carrageenan …

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Determination of Octenylsuccinic Acid in Nutritional Products

Paul W. Johns, Wesley A Jacobs, Maggie M. Hroncich, Mustafa Vurma

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