Tinatin Döölotkeldieva

Phytoparasitic Nematodes Affecting Kyrgyzstan’s Vegetable Crops and Examining the Predatory Fungus Arthrobotrys oligospora as a Biological Control Agent

Tinatin Döölotkeldieva

Parasitic nematodes are some of the most harmful plant pathogens, and their detrimental impact on crops is increasing in Kyrgyzstan. Notably, the potato stem nematode (Ditylenchus destructor) and the stalk garlic nematode (Ditylenchus dipsaci) threaten economically essential crops such as potatoes, garlic, …

The bacterial species’ degradation activities at maximum threshold doses of glyphosate across different pH levels and temperature glyphosate biodegradation by soil bacteria at high doses under variable pH and temperature

Tinatin Döölotkeldieva, Saykal Bobusheva, Mahabat Konurbaeva

Glyphosate (N- (phosphonomethyl) glycine) is an organophosphorus compound and one of the most widely used herbicides worldwide. However, concerns about its environmental impact have prompted researchers to investigate its degradation process. This study addresses several key questions, particularly concerning the concentrations of …

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Mixed infections of cucumber fruits caused by diverse fungal pathogens under greenhouse conditions

Tinatin Döölotkeldieva, Uultai Saparbekova, Batma Zhusupova

Cucumber is among the most widely cultivated crops in greenhouses conditions in Kyrgyzstan. In recent years, parthenocarpic heterotic hybrids have become common in greenhouse production. However, the resistance or susceptibility of these hybrid varieties to fungal and bacterial diseases remains largely unexplored. …

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Identification of seed-borne diseases in sugar beet and applying bioagents to enhance seed quality

Tinatin Döölotkeldieva, Astra Zamirbekova

Sugar beet (Beta vulgaris L.) is not just a crop but a vital economic resource that produces sugar, biofuel, and animal feed. This study focused on the mycoflora of seeds from two varieties of sugar beets – local and imported. The international …

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ENSURING THE QUALITY OF PHARMACEUTICAL PRODUCTION IN ACCORDANCE WITH GOOD MANUFACTURING PRACTICE REQUIREMENTS

A.Y. YELUBAEVA, А.К. САДАНОВ, О.N. LAHK, С.Э. ОРАЗЫМБЕТ et autres

This article presents the results of developing Kazakh national standards for Good Manufacturing Practice (GMP) in pharmaceutical production based on international standards, particularly those of the European Union. Implementation of good Manufacturing Practices (GMP) and quality system in pharmaceutical production. Ensuring a …

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Epidemiological description of fire blight introduction patterns to Central Asia and the Caucasus region based on CRISPR spacer typing and genome analysis

Fabio Rezzonico, Saikal Bobushova, Dali Gaganidze, Mahabat Konurbaeva et autres

Abstract In the last two decades, fire blight has progressively spread eastward from Europe and the Mediterranean area to several pome-fruit producing regions of Asia. Its causative agent, the bacterial pathogen Erwinia amylovora , was detected in several new countries, including Georgia, …

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Malus Domestic’s Bacterial and Fungal Diseases Impact in Kyrgyzstan Fruit Production

Tinatin Döölotkeldieva

Kyrgyzstan is not just a home to wild apple trees, but a global sanctuary for these unique species. The largest concentration of these wild apple trees can be found in the natural walnut forests and the Sary Chelek reservation. The Malus niedzwetzkiana …

Recent progress in the development of encapsulated fertilizers for time-controlled release

Alexey P. Dovzhenko, Olga A. Yapryntseva, Kirill Sinyashin, Tinatin Döölotkeldieva et autres

This review describes the latest achievements in the development of encapsulated controlled-release fertilizers, which encompasses sustainability issues in agriculture. The research community's interest in this particular area of science has doubled over the last couple of years due to the yearly increasing …

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In vitro and in vivo screening of bacterial species from contaminated soil for heavy metal biotransformation activity

Tinatin Döölotkeldieva, Saykal Bobusheva, Mahabat Konurbaeva

Heavy metals (HMs) are widely used in various industries. High concentrations of HMs can be severely toxic to plants, animals and humans. Microorganism-based bioremediation has shown significant potential in degrading and detoxifying specific HM contaminants. In this study, we cultivated a range …

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In situ microbial bioremediation of obsolete pesticides at their disposal sites

Tinatin Döölotkeldieva, Mahabat Konurbaeva, Saykal Bobusheva

Soil pollution by pesticides is a global problem in many countries, including Kyrgyzstan. Currently, 50 storage facilities for obsolete banned pesticides exist, severely threatening the surrounding populations and environment. In this study, in situ bioremediation technology was used to remove pesticide contamination …

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РОЛЬ ПРОБИОТИКОВ В ЛЕЧЕНИИ КИШЕЧНЫХ ИНФЕКЦИЙ

A.D. MASSIRBAEVA, Sirina Zhantlessova, M.B. YERDENBEKOVA, Tinatin Döölotkeldieva et autres

Numerous studies have proven the effectiveness of probiotics in the treatment and prevention of intestinal infections and many other diseases. The main mechanisms of action of probiotics are explained. The use of probiotics to improve gut health has been recommended for many …

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In vitro Screening of Natural Metarhizium spp. Isolates for Bioinsecticidal and Biofungicidal Activity

Tinatin Döölotkeldieva, Sagynych Tolonbekova, Saykal Bobusheva

Aims: To increase conidia production of local Metarhizium spp—strains by selecting the low-cost media to test obtained bioformulation against the sucking pests and fungal plant pathogens. Study Design: The phytophages like black bean aphid (Aphis fabae), a scale insect (Aspidiotus nerii) and …

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