Sirina Zhantlessova

Optimized Food-Grade Semi-Synthetic Culture Medium and Freeze-Drying Approach with Antidiabetic Cryoprotectants for Akkermansia Muciniphila

Zhazira Khamitkyzy, Aida Kistaubayeva, Irina Savitskaya, Dina Shokatayeva et autres

Akkermansia muciniphila is a mucin-degrading intestinal bacterium known for its beneficial effects, including antidiabetic and antiobesity effects.It typically grows on media supplemented with animalderived mucin.However, the use of such substrates in cultivation is unsuitable for food applications due to ethical and dietary …

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Correction: Zhantlessova et al. Advanced “Green” Prebiotic Composite of Bacterial Cellulose/Pullulan Based on Synthetic Biology-Powered Microbial Coculture Strategy. Polymers 2022, 14, 3224

Sirina Zhantlessova, Irina Savitskaya, Aida Kistaubayeva, Ludmila V. Ignatova et autres

In the original publication [...].

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ПРОБИОТИКИ ДЛЯ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ АНТИБИОТИКО-АССОЦИИРОВАННОЙ ДИАРЕИ

Sirina Zhantlessova, А.К. САДАНОВ, B.B. BAIMAKHANOVA, С.Э. ОРАЗЫМБЕТ et autres

The use of probiotics has increased significantly over recent decades. This has been accompanied by an increasing amount of literature demonstrating their importance in clinical practice. Antibacterial drugs, like many other ones, have side effects, one of which is antibiotic-associated diarrhea (AAD). …

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РОЛЬ ПРОБИОТИКОВ В ЛЕЧЕНИИ КИШЕЧНЫХ ИНФЕКЦИЙ

A.D. MASSIRBAEVA, Sirina Zhantlessova, M.B. YERDENBEKOVA, Tinatin Döölotkeldieva et autres

Numerous studies have proven the effectiveness of probiotics in the treatment and prevention of intestinal infections and many other diseases. The main mechanisms of action of probiotics are explained. The use of probiotics to improve gut health has been recommended for many …

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РАЗНООБРАЗИЕ АКТИНОМИЦЕТОВ И ИХ РОЛЬ КАК ПРОДУЦЕНТОВ АНТИБИОТИКОВ

Sirina Zhantlessova, А.К. САДАНОВ, B.B. BAIMAKHANOVA, О.N. LAHK et autres

Actinomycetes are universal producers of a variety of secondary metabolites, including antibiotics. According to the World Health Organization (WHO), antibiotic resistance is currently one of the biggest threats to human health, food security and development. This review summarizes information about actinomycetes and …

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ПРОТИВОГРИБКОВЫЕ ЛЕКАРСТВЕННЫЕ СРЕДСТВА ДЛЯ ЛЕЧЕНИЯ ВАГИНАЛЬНОГО КАНДИДОЗА

Z.Zh. TURLYBAYEVA⃰, B.B. BAYMAKHANOVA, Liliya Ibragimova, А.К. САДАНОВ et autres

Fungal infections can significantly alter the normal microflora of the body. Long-term use of ineffective medications in the treatment of vaginal candidiasis leads to drug resistance of infectious agents, and their systemic absorption leads to metabolic disorders. The transition of the disease …

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Prebiotic Cellulose–Pullulan Matrix as a “Vehicle” for Probiotic Biofilm Delivery to the Host Large Intestine

Irina Savitskaya, Sirina Zhantlessova, Aida Kistaubayeva, Ludmila V. Ignatova et autres

GG (LGG) bacteria in biofilm form. The new composition allows for delivering the bacteria to the digestive tract in a manner that improves their robustness compared with planktonic cells and released biofilm cells. Granules consisting of a polysaccharide matrix with probiotic biofilms …

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The Effect of Encapsulating a Prebiotic-Based Biopolymer Delivery System for Enhanced Probiotic Survival

Aida Kistaubayeva, M. A. Abdulzhanova, Sirina Zhantlessova, Irina Savitskaya et autres

Orally delivered probiotics must survive transit through harsh environments during gastrointestinal (GI) digestion and be delivered and released into the target site. The aim of this work was to evaluate the survivability and delivery of gel-encapsulated Lactobacillus rhamnosus GG (LGG) to the …

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Advanced “Green” Prebiotic Composite of Bacterial Cellulose/Pullulan Based on Synthetic Biology-Powered Microbial Coculture Strategy

Sirina Zhantlessova, Irina Savitskaya, Aida Kistaubayeva, Ludmila V. Ignatova et autres

Bacterial cellulose (BC) is a biopolymer produced by different microorganisms, but in biotechnological practice, Komagataeibacter xylinus is used. The micro- and nanofibrillar structure of BC, which forms many different-sized pores, creates prerequisites for the introduction of other polymers into it, including those …

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Selection and optimization of cultivation conditions for bacterial cellulose producer

Sirina Zhantlessova, Zh. Khamitkyzy, A.B. Talipova, I.S. Savitskaya et autres

The aim of this study was to increase productivity of Komagataeibacter xylinus C3 strain on nutrient media using industrial wastes as carbon source. By-product of sugar production, molasses, was selected for the cultivation of bacterial cellulose (BC) producer. It has been shown …

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Morphological and Physicochemical Properties of Nanostructured Cellulose Obtained through Chemical and Biological Methods

Natalia V. Vassilyeva, Irina Savitskaya, Sirina Zhantlessova, З. А. Мансуров et autres

The authors obtained samples of chemically pure, crystalline, microand nanostructured cellulose of various modifications using two approaches – biological and chemical. They studied these cellulose samples via scanning electron microscopy (SEM), thermogravimetric analysis, and infrared (IR) spectroscopy. To prepare cellulose microcrystals, they …